Search Results - "HORTON, Paul"

MethylSeqLogo: DNA methylation smart sequence logos by Hsu, Fei-Man, Horton, Paul

“…Some transcription factors, MYC for example, bind sites of potentially methylated DNA. This may increase binding specificity as such sites are (1) highly…”
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Portraying monsters: framing school bullying through a macro lens by Horton, Paul

“…This article critically considers the discourse on school bullying through the conceptual framework of lenses and argues that a macro lens has been utilised by…”
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A commentary on evaluation of the evenness score in next-generation sequencing by Horton, Paul

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Adaptive seeds tame genomic sequence comparison by Kiełbasa, Szymon M, Wan, Raymond, Sato, Kengo, Horton, Paul, Frith, Martin C

“…The main way of analyzing biological sequences is by comparing and aligning them to each other. It remains difficult, however, to compare modern…”
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Molecular architecture of the active mitochondrial protein gate by Shiota, Takuya, Imai, Kenichiro, Qiu, Jian, Hewitt, Victoria L., Tan, Khershing, Shen, Hsin-Hui, Sakiyama, Noriyuki, Fukasawa, Yoshinori, Hayat, Sikander, Kamiya, Megumi, Elofsson, Arne, Tomii, Kentaro, Horton, Paul, Wiedemann, Nils, Pfanner, Nikolaus, Lithgow, Trevor, Endo, Toshiya

“…Mitochondria fulfill central functions in cellular energetics, metabolism, and signaling. The outer membrane translocator complex (the TOM complex) imports…”
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Neural correlates of alexithymia: A meta-analysis of emotion processing studies by VAN DER VELDE, Jorien, SERVAAS, Michelle N, GOERLICH, Katharina S, BRUGGEMAN, Richard, HORTON, Paul, COSTAFREDA, Sergi G, ALEMAN, André

“…Alexithymia is a personality trait characterized by difficulties in the experience and cognitive processing of emotions. It is considered a risk factor for a…”
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Parameters for accurate genome alignment by Frith, Martin C, Hamada, Michiaki, Horton, Paul

“…Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and…”
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Extensive cargo identification reveals distinct biological roles of the 12 importin pathways by Kimura, Makoto, Morinaka, Yuriko, Imai, Kenichiro, Kose, Shingo, Horton, Paul, Imamoto, Naoko

“…Vast numbers of proteins are transported into and out of the nuclei by approximately 20 species of importin-β family nucleocytoplasmic transport receptors…”
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Juridification and judgement calls: Swedish schoolteachers' reflections on dealing with bullying, harassment, and degrading treatment by Horton, Paul, Forsberg, Camilla, Thornberg, Robert

“…While teachers are obliged to report and investigate incidents of bullying, harassment, and degrading treatment in Swedish schools, research suggests that they…”
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ValidNESs: a database of validated leucine-rich nuclear export signals by Fu, Szu-Chin, Huang, Hsuan-Cheng, Horton, Paul, Juan, Hsueh-Fen

“…ValidNESs (http://validness.ym.edu.tw/) is a new database for experimentally validated leucine-rich nuclear export signal (NES)-containing proteins. The…”
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Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding by Kimura, Makoto, Imai, Kenichiro, Morinaka, Yuriko, Hosono-Sakuma, Yoshiko, Horton, Paul, Imamoto, Naoko

“…Importin-(Imp)β family nucleocytoplasmic transport receptors (NTRs) are supposed to bind to their cargoes through interaction between a confined interface on…”
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Unpacking the bullying doll: Reflections from a fieldwork at the social-ecological square by Horton, Paul

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Long non-coding RNA 2310069B03Rik functions as a suppressor of Ucp1 expression under prolonged cold exposure in murine beige adipocytes by Iwase, Mari, Sakai, Shoko, Seno, Shigeto, Yeh, Yu-Sheng, Kuo, Tony, Takahashi, Haruya, Nomura, Wataru, Jheng, Huei-Fen, Horton, Paul, Osato, Naoki, Matsuda, Hideo, Inoue, Kazuo, Kawada, Teruo, Goto, Tsuyoshi

“…Specific conditions, such as exposure to cold, can induce the production of brown-like adipocytes in white adipose tissue. These adipocytes express high levels…”
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"It's hard to be everywhere": Teachers' perspectives on spatiality, school design and school bullying by Horton, Paul, sberg, Camilla, Thornberg, Robert

“…In this qualitative study, we explore teachers perspectives on spatiality, school design and school bullying. The study is part of a larger, ongoing…”
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Estimating genome-wide off-target effects for pyrrole-imidazole polyamide binding by a pathway-based expression profiling approach by Lin, Jason, Krishnamurthy, Sakthisri, Yoda, Hiroyuki, Shinozaki, Yoshinao, Watanabe, Takayoshi, Koshikawa, Nobuko, Takatori, Atsushi, Horton, Paul, Nagase, Hiroki

“…In the search for new pharmaceutical leads, especially with DNA-binding molecules or genome editing methods, the issue of side and off-target effects have…”
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Sequence homology in eukaryotes (SHOE): interactive visual tool for promoter analysis by Polouliakh, Natalia, Horton, Paul, Shibanai, Kazuhiro, Takata, Kodai, Ludwig, Vanessa, Ghosh, Samik, Kitano, Hiroaki

“…Microarray and DNA-sequencing based technologies continue to produce enormous amounts of data on gene expression. This data has great potential to illuminate…”
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EAGLE: Explicit Alternative Genome Likelihood Evaluator by Kuo, Tony, Frith, Martin C, Sese, Jun, Horton, Paul

“…Reliable detection of genome variations, especially insertions and deletions (indels), from single sample DNA sequencing data remains challenging, partially…”
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A bioinformatics potpourri by Schönbach, Christian, Li, Jinyan, Ma, Lan, Horton, Paul, Sjaugi, Muhammad Farhan, Ranganathan, Shoba

“…The 16th International Conference on Bioinformatics (InCoB) was held at Tsinghua University, Shenzhen from September 20 to 22, 2017. The annual conference of…”
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Identification of Cargo Proteins Specific for the Nucleocytoplasmic Transport Carrier Transportin by Combination of an in Vitro Transport System and Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Quantitative Proteomics by Kimura, Makoto, Kose, Shingo, Okumura, Nobuaki, Imai, Kenichiro, Furuta, Maiko, Sakiyama, Noriyuki, Tomii, Kentaro, Horton, Paul, Takao, Toshifumi, Imamoto, Naoko

“…The human importin-β family consists of 21 nucleocytoplasmic transport carrier proteins that carry proteins and RNAs across the nuclear envelope through…”
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Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome by Lin, Jason, Hiraoka, Kiriko, Watanabe, Takayoshi, Kuo, Tony, Shinozaki, Yoshinao, Takatori, Atsushi, Koshikawa, Nobuko, Chandran, Anandhakumar, Otsuki, Joe, Sugiyama, Hiroshi, Horton, Paul, Nagase, Hiroki

“…Pyrrole-imidazole polyamides are versatile DNA minor groove binders and attractive therapeutic options against oncological targets, especially upon…”
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