Search Results - "HORNSHØJ, Henrik"

DNA hypermethylation and differential gene expression associated with Klinefelter syndrome by Skakkebæk, Anne, Nielsen, Morten Muhlig, Trolle, Christian, Vang, Søren, Hornshøj, Henrik, Hedegaard, Jakob, Wallentin, Mikkel, Bojesen, Anders, Hertz, Jens Michael, Fedder, Jens, Østergaard, John Rosendahl, Pedersen, Jakob Skou, Gravholt, Claus Højbjerg

“…Klinefelter syndrome (KS) has a prevalence ranging from 85 to 250 per 100.000 newborn boys making it the most frequent sex chromosome aneuploidy in the general…”
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Mutational Context and Diverse Clonal Development in Early and Late Bladder Cancer by Nordentoft, Iver, Lamy, Philippe, Birkenkamp-Demtröder, Karin, Shumansky, Karey, Vang, Søren, Hornshøj, Henrik, Juul, Malene, Villesen, Palle, Hedegaard, Jakob, Roth, Andrew, Thorsen, Kasper, Høyer, Søren, Borre, Michael, Reinert, Thomas, Fristrup, Niels, Dyrskjøt, Lars, Shah, Sohrab, Pedersen, Jakob Skou, Ørntoft, Torben F.

“…Bladder cancer (or urothelial cell carcinoma [UCC]) is characterized by field disease (malignant alterations in surrounding mucosa) and frequent recurrences…”
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A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data by Bertl, Johanna, Guo, Qianyun, Juul, Malene, Besenbacher, Søren, Nielsen, Morten Muhlig, Hornshøj, Henrik, Pedersen, Jakob Skou, Hobolth, Asger

“…Detailed modelling of the neutral mutational process in cancer cells is crucial for identifying driver mutations and understanding the mutational mechanisms…”
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Epigenetic and transcriptomic consequences of excess X‐chromosome material in 47,XXX syndrome—A comparison with Turner syndrome and 46,XX females by Nielsen, Morten Muhlig, Trolle, Christian, Vang, Søren, Hornshøj, Henrik, Skakkebæk, Anne, Hedegaard, Jakob, Nordentoft, Iver, Pedersen, Jakob Skou, Gravholt, Claus Højbjerg

“…47,XXX (triple X) and Turner syndrome (45,X) are sex chromosomal abnormalities with detrimental effects on health with increased mortality and morbidity. In…”
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Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate by Juul, Malene, Bertl, Johanna, Guo, Qianyun, Nielsen, Morten Muhlig, Świtnicki, Michał, Hornshøj, Henrik, Madsen, Tobias, Hobolth, Asger, Pedersen, Jakob Skou

“…Non-coding mutations may drive cancer development. Statistical detection of non-coding driver regions is challenged by a varying mutation rate and uncertainty…”
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Transcriptomic and proteomic profiling of two porcine tissues using high-throughput technologies by Hornshøj, Henrik, Bendixen, Emøke, Conley, Lene N, Andersen, Pernille K, Hedegaard, Jakob, Panitz, Frank, Bendixen, Christian

“…The recent development within high-throughput technologies for expression profiling has allowed for parallel analysis of transcriptomes and proteomes in…”
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Regulation of basal resistance by a powdery mildew-induced cysteine-rich receptor-like protein kinase in barley by RAYAPURAM, CBGOWDA, JENSEN, MICHAEL K., MAISER, FABIAN, SHANIR, JOHANNA VIKGREN, HORNSHØJ, HENRIK, RUNG, JESPER H., GREGERSEN, PER L., SCHWEIZER, PATRICK, COLLINGE, DAVID B., LYNGKJÆR, MICHAEL F.

“…SUMMARY The receptor‐like protein kinases (RLKs) constitute a large and diverse group of proteins controlling numerous plant physiological processes, including…”
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Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival by Hornshøj, Henrik, Nielsen, Morten Muhlig, Sinnott-Armstrong, Nicholas A., Świtnicki, Michał P., Juul, Malene, Madsen, Tobias, Sallari, Richard, Kellis, Manolis, Ørntoft, Torben, Hobolth, Asger, Pedersen, Jakob Skou

“…Cancer develops by accumulation of somatic driver mutations, which impact cellular function. Mutations in non-coding regulatory regions can now be studied…”
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Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing by Wernersson, Rasmus, Schierup, Mikkel H, Jørgensen, Frank G, Gorodkin, Jan, Panitz, Frank, Staerfeldt, Hans-Henrik, Christensen, Ole F, Mailund, Thomas, Hornshøj, Henrik, Klein, Ami, Wang, Jun, Liu, Bin, Hu, Songnian, Dong, Wei, Li, Wei, Wong, Gane K S, Yu, Jun, Wang, Jian, Bendixen, Christian, Fredholm, Merete, Brunak, Søren, Yang, Huanming, Bolund, Lars

“…Comparative whole genome analysis of Mammalia can benefit from the addition of more species. The pig is an obvious choice due to its economic and medical…”
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Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags by Gorodkin, Jan, Cirera, Susanna, Hedegaard, Jakob, Gilchrist, Michael J, Panitz, Frank, Jørgensen, Claus, Scheibye-Knudsen, Karsten, Arvin, Troels, Lumholdt, Steen, Sawera, Milena, Green, Trine, Nielsen, Bente J, Havgaard, Jakob H, Rosenkilde, Carina, Wang, Jun, Li, Heng, Li, Ruiqiang, Liu, Bin, Hu, Songnian, Dong, Wei, Li, Wei, Yu, Jun, Wang, Jian, Staefeldt, Hans-Henrik, Wernersson, Rasmus, Madsen, Lone B, Thomsen, Bo, Hornshøj, Henrik, Bujie, Zhan, Wang, Xuegang, Wang, Xuefei, Bolund, Lars, Brunak, Søren, Yang, Huanming, Bendixen, Christian, Fredholm, Merete

“…Knowledge of the structure of gene expression is essential for mammalian transcriptomics research. We analyzed a collection of more than one million porcine…”
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Microarray expression profiles of 20.000 genes across 23 healthy porcine tissues by Hornshøj, Henrik, Conley, Lene Nagstrup, Hedegaard, Jakob, Sørensen, Peter, Panitz, Frank, Bendixen, Christian

“…Gene expression microarrays have been intensively applied to screen for genes involved in specific biological processes of interest such as diseases or…”
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Gene expression profiling of porcine skeletal muscle in the early recovery phase following acute physical activity by Jensen, Jeanette H., Conley, Lene N., Hedegaard, Jakob, Nielsen, Mathilde, Young, Jette F., Oksbjerg, Niels, Hornshøj, Henrik, Bendixen, Christian, Thomsen, Bo

“…Acute physical activity elicits changes in gene expression in skeletal muscles to promote metabolic changes and to repair exercise‐induced muscle injuries. In…”
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A robust linkage map of the porcine autosomes based on gene-associated SNPs by Vingborg, Rikke K K, Gregersen, Vivi R, Zhan, Bujie, Panitz, Frank, Høj, Anette, Sørensen, Kirsten K, Madsen, Lone B, Larsen, Knud, Hornshøj, Henrik, Wang, Xuefei, Bendixen, Christian

“…Genetic linkage maps are necessary for mapping of mendelian traits and quantitative trait loci (QTLs). To identify the actual genes, which control these…”
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Gene expression profiles in liver of pigs with extreme high and low levels of androstenone by Moe, Maren, Lien, Sigbjørn, Bendixen, Christian, Hedegaard, Jakob, Hornshøj, Henrik, Berget, Ingunn, Meuwissen, Theo H E, Grindflek, Eli

“…Boar taint is the unpleasant odour and flavour of the meat of uncastrated male pigs that is primarily caused by high levels of androstenone and skatole in…”
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Comparative analysis of protein coding sequences from human, mouse and the domesticated pig by Jørgensen, Frank Grønlund, Hobolth, Asger, Hornshøj, Henrik, Bendixen, Christian, Fredholm, Merete, Schierup, Mikkel Heide

“…The availability of abundant sequence data from key model organisms has made large scale studies of molecular evolution an exciting possibility. Here we use…”
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SNP mining porcine ESTs with MAVIANT, a novel tool for SNP evaluation and annotation by Panitz, Frank, Stengaard, Henrik, Hornshøj, Henrik, Gorodkin, Jan, Hedegaard, Jakob, Cirera, Susanna, Thomsen, Bo, Madsen, Lone B., Høj, Anette, Vingborg, Rikke K., Zahn, Bujie, Wang, Xuegang, Wang, Xuefei, Wernersson, Rasmus, Jørgensen, Claus B., Scheibye-Knudsen, Karsten, Arvin, Troels, Lumholdt, Steen, Sawera, Milena, Green, Trine, Nielsen, Bente J., Havgaard, Jakob H., Brunak, Søren, Fredholm, Merete, Bendixen, Christian

“…Motivation: Single nucleotide polymorphisms (SNPs) analysis is an important means to study genetic variation. A fast and cost-efficient approach to identify…”
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Molecular characterisation of the early response in pigs to experimental infection with Actinobacillus pleuropneumoniae using cDNA microarrays by Hedegaard, Jakob, Skovgaard, Kerstin, Mortensen, Shila, Sørensen, Peter, Jensen, Tim K, Hornshøj, Henrik, Bendixen, Christian, Heegaard, Peter M H

“…The bacterium Actinobacillus pleuropneumoniae is responsible for porcine pleuropneumonia, a widespread, highly contagious and often fatal respiratory disease…”
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A genome-wide association scan in pig identifies novel regions associated with feed efficiency trait by Sahana, Goutam, Kadlecová, Veronika, Hornshøj, Henrik, Nielsen, Bjarne, Christensen, Ole F

“…Feed conversion ratio (FCR) is an economically important trait in pigs, and feed accounts for a significant proportion of the costs involved in pig production…”
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Analysis of the real EADGENE data set: Comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (Open Access publication) by Jaffrezic, F, De Koning, D-J, Boettcher, P J, Bonnet, A, Buitenhuis, B, Closset, R, Dejean, S, Delmas, C, Detilleux, J C, Dovc, P, Duval, M, Foulley, J-L, Hedegaard, J, Hornshoej, H

“…A large variety of methods has been proposed in the literature for microarray data analysis. The aim of this paper was to present techniques used by the…”
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Gene set analysis methods applied to chicken microarray expression data by Skarman, Axel, Jiang, Li, Henrik, Hornshøj, Buitenhuis, Bart, Hedegaard, Jakob, Conley, Lene N, Sørensen, Peter

“…Gene set analysis is considered to be a way of improving our biological interpretation of the observed expression patterns. This paper describes different…”
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