Search Results - "HORN, H. F"

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway by Horn, H F, Vousden, K H

“…MDM2 is a ubiquitin ligase that plays a key role in regulating the stability of the p53 tumor suppressor protein. Several proteins have been shown to activate…”
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Coping with stress: multiple ways to activate p53 by Horn, H F, Vousden, K H

“…Over the years, p53 has been shown to sit at the centre of an increasingly complex web of incoming stress signals and outgoing effector pathways. The number…”
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Centrosome hyperamplification in human cancer : chromosome instability induced by p53 mutation and/or Mdm2 overexpression by CARROLL, P. E, OKUDA, M, HORN, H. F, BIDDINGER, P, STAMBROOK, P. J, GLEICH, L. L, LI, Y.-Q, TARAPORE, P, FUKASAWA, K

“…We have previously reported that loss of p53 tumor suppressor protein results in centrosome hyperamplification, which leads to aberrant mitosis and chromosome…”
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Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression by MUSSMAN, J. G, HORN, H. F, CARROLL, P. E, OKUDA, M, TARAPORE, P, DONEHOWER, L. A, FUKASAWA, K

“…Centrosome hyperamplification and the consequential mitotic defects contribute to chromosome instability in cancers. Loss or mutational inactivation of p53 has…”
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Specific phosphorylation of nucleophosmin on Thr(199) by cyclin-dependent kinase 2-cyclin E and its role in centrosome duplication by Tokuyama, Y, Horn, H F, Kawamura, K, Tarapore, P, Fukasawa, K

“…The kinase activity of cyclin-dependent kinase 2 (CDK2)-cyclin E is required for centrosomes to initiate duplication. We have recently found that nucleophosmin…”
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Nucleophosmin/B23 Is a Target of CDK2/Cyclin E in Centrosome Duplication by Okuda, Masaru, Horn, Henning F, Tarapore, Pheruza, Tokuyama, Yukari, Smulian, A.George, Chan, Pui-Kwong, Knudsen, Erik S, Hofmann, Irene A, Snyder, Jean D, Bove, Kevin E, Fukasawa, Kenji

“…In animal cells, duplication of centrosomes and DNA is coordinated. Since CDK2/cyclin E triggers initiation of both events, activation of CDK2/cyclin E is…”
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Difference in the centrosome duplication regulatory activity among p53 'hot spot' mutants : potential role of Ser 315 phosphorylation-dependent centrosome binding of p53 by TARAPORE, Pheruza, TOKUYAMA, Yukari, HORN, Henning F, FUKASAWA, Kenji

“…The p53 tumor suppressor protein regulates centrosome duplication through multiple pathways, and p21(Waf1/Cip1) (Waf1), a major target of p53's transactivation…”
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The voluntary health agency--is it still necessary? by Horn, F H

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Coping with stress : multiple ways to activate p53: Cancer: Biology and therapeutics. A tribute to George Vande Woude by HORN, H. F, VOUSDEN, K. H

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PML regulates p53 stability by sequestering Mdm2 to the nucleolus by Pandolfi, Pier Paolo, Bernardi, Rosa, Scaglioni, Pier Paolo, Bergmann, Stephan, Horn, Henning F, Vousden, Karen H

“…The promyelocytic leukaemia (PML) tumour-suppressor protein potentiates p53 function by regulating post-translational modifications, such as CBP-dependent…”
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A NEW CRYSTALLINE MODIFICATION OF BORON by McCarty, L. V, Kasper, J. S, Horn, F. H, Decker, B. F, Newkirk, A. E

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Thermal Conductivity of Boron and Some Boron Compounds by Slack, Glen A., Oliver, D. W., Horn, F. H.

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Holes in Crystals by HORN, F. H, FULLAM, E. F, KASPER, J. S

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Changing times and the challenge to health by HORN, F H

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Direct regulation of the centrosome duplication cycle by the p53-p21 super(Waf1/Cip1) pathway by Tarapore, P, Horn, H F, Tokuyama, Yukari, Fukasawa, Kenji

“…The function of the centrosomes to direct mitotic spindles is critical for accurate chromosome transmission to daughter cells. Since each daughter cell…”
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Specific Phosphorylation of Nucleophosmin on Thr super(199) by Cyclin-dependent Kinase 2-Cyclin E and Its Role in Centrosome Duplication by Tokuyama, Y, Horn, H F, Kawamura, K, Tarapore, P, Fukasawa, K

“…The kinase activity of cyclin-dependent kinase 2 (CDK2)-cyclin E is required for centrosomes to initiate duplication. We have recently found that nucleophosmin…”
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Cancer Guarding the guardian? by Vousden, Karen H, Horn, Henning F

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Direct regulation of the centrosome duplication cycle by the p53-p21Waf1/Cip1 pathway by TARAPORE, Pheruza, HORN, Henning F, TOKUYAMA, Yukari, FUKASAWA, Kenji

“…The function of the centrosomes to direct mitotic spindles is critical for accurate chromosome transmission to daughter cells. Since each daughter cell…”
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Active RB Elicits Late G1/S Inhibition by Angus, Steven P., Fribourg, Anne F., Markey, Michael P., Williams, Sarah L., Horn, Henning F., DeGregori, James, Kowalik, Timothy F., Fukasawa, Kenji, Knudsen, Erik S.

“…The retinoblastoma tumor suppressor protein (RB) is activated/dephosphorylated to mediate cell cycle inhibition in response to antimitogenic signals. To…”
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The chemical erosion of steel by hot gases under pressure by EVANS, R C, HORN, F H

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