Search Results - "HORIUCHI, Yoshinobu"

A national reference for inactivated polio vaccine derived from Sabin strains in Japan by Shirato, Haruko, Someya, Yuichi, Ochiai, Masaki, Horiuchi, Yoshinobu, Takahashi, Motohide, Takeda, Naokazu, Wakabayashi, Kengo, Ouchi, Yasumitsu, Ota, Yoshihiro, Tano, Yoshio, Abe, Shinobu, Yamazaki, Shudo, Wakita, Takaji

“…Abstract As one aspect of its campaign to eradicate poliomyelitis, the World Health Organization (WHO) has encouraged development of the inactivated polio…”
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Development and Evaluation of a Loop-Mediated Isothermal Amplification Method for Rapid Diagnosis of Bordetella pertussis Infection by KAMACHI, Kazunari, TOYOIZUMI-AJISAKA, Hiromi, TODA, Kohei, SANN CHAN SOEUNG, SARATH, Svay, NARETH, Ya, HORIUCHI, Yoshinobu, KOJIMA, Kazunobu, TAKAHASHI, Motohide, ARAKAWA, Yoshichika

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Lipopolysaccaride-binding peptides obtained by phage display method by Matsumoto, Megumi, Horiuchi, Yoshinobu, Yamamoto, Akihiko, Ochiai, Masaki, Niwa, Makoto, Takagi, Takashi, Omi, Hiroyuki, Kobayashi, Tomomi, Suzuki, Masatsugu-Matt

“…Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative bacteria. It has strong toxicity and might cause sepsis or septic shock…”
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Comparison of acellular pertussis-based combination vaccines by Japanese control tests for toxicities and laboratory models for local reaction by Kataoka, Michiyo, Yamamoto, Akihiko, Ochiai, Masaki, Harashima, Ayako, Nagata, Noriyo, Hasegawa, Hideki, Kurata, Takeshi, Horiuchi, Yoshinobu

“…Abstract Two batches each of diphtheria–tetanus–acellular pertussis vaccine (DTaP) and that combined with inactivated polio vaccine purchased from the U.S.A.,…”
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Antigenic Divergence Suggested by Correlation between Antigenic Variation and Pulsed-Field Gel Electrophoresis Profiles of Bordetella pertussis Isolates in Japan by KODAMA, Atsuko, KAMACHI, Kazunari, HORIUCHI, Yoshinobu, KONDA, Toshifumi, ARAKAWA, Yoshichika

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Application of quantitative gene expression analysis for pertussis vaccine safety control by Hamaguchi, Isao, Imai, Jun-ichi, Momose, Haruka, Kawamura, Mika, Mizukami, Takuo, Naito, Seishiro, Maeyama, Jun-ichi, Masumi, Atsuko, Kuramitsu, Madoka, Takizawa, Kazuya, Kato, Hiroshi, Mizutani, Tetsuya, Horiuchi, Yoshinobu, Nomura, Nobuo, Watanabe, Shinya, Yamaguchi, Kazunari

“…Abstract Although vaccines are routinely used to prevent infectious diseases, little is known about the comprehensive influences caused by vaccines. In this…”
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Two vaccine toxicity-related genes Agp and Hpx could prove useful for pertussis vaccine safety control by Hamaguchi, Isao, Imai, Jun-ichi, Momose, Haruka, Kawamura, Mika, Mizukami, Takuo, Kato, Hiroshi, Naito, Seishiro, Maeyama, Jun-ichi, Masumi, Atsuko, Kuramitsu, Madoka, Takizawa, Kazuya, Mochizuki, Masayo, Ochiai, Masaki, Yamamoto, Akihiko, Horiuchi, Yoshinobu, Nomura, Nobuo, Watanabe, Shinya, Yamaguchi, Kazunari

“…Abstract Conventional animal tests such as leukocytosis promoting tests have been used for decades to evaluate toxicity of pertussis vaccine. Here, we examined…”
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A poliomyelitis model through mucosal infection in transgenic mice bearing human poliovirus receptor, TgPVR21 by Nagata, Noriyo, Iwasaki, Takuya, Ami, Yasushi, Sato, Yuko, Hatano, Ikuyoshi, Harashima, Ayako, Suzaki, Yuriko, Yoshii, Takao, Hashikawa, Tsutomu, Sata, Tetsutaro, Horiuchi, Yoshinobu, Koike, Satoshi, Kurata, Takeshi, Nomoto, Akio

“…Transgenic mice bearing the human poliovirus receptor (TgPVR) are less susceptible to oral inoculation, although they are susceptible to parenteral…”
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Quality control of diphtheria tetanus acellular pertussis combined (DTaP) vaccines in Japan by Horiuchi, Y, Takahashi, M, Konda, T, Ochiai, M, Yamamoto, A, Kataoka, M, Toyoizumi, H, Arakawa, Y

“…Diphtheria tetanus acellular pertussis combined (DTaP) vaccines have been successfully used in Japan by controlling their potencies and toxicities with animal…”
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A Quantitative In Vitro Assay Method for Detecting Biological Activity of Endotoxin Using Prostaglandin E2 Induction in Rabbit Peripheral Blood by Ochiai, Masaki, Kataoka, Michiyo, Toyoizumi, Hiromi, Yamamoto, Akihiko, Kamachi, Kazunari, Horiuchi, Yoshinobu

“…The pyrogen test and the endotoxin test (the LAL test) have been playing crucial roles in detecting endotoxin in parenteral drugs. The current test methods,…”
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Augmenting Effect of Antibiotics on Endotoxin Activity May Cause a Safety Problem by Yamamoto, Akihiko, Sakai, Takeo, Ochiai, Masaki, Kamachi, Kazunari, Kataoka, Michiyo, Toyoizumi, Hiromi, Arakawa, Yoshichika, Horiuchi, Yoshinobu

“…Enhancing/interfering effect of antibiotics on endotoxin was evaluated using the endotoxin test and the cell line assay in 28SC cells that has a responsiveness…”
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Endotoxin content in Haemophilus influenzae type b vaccine by Ochiai, Masaki, Kataoka, Michiyo, Toyoizumi, Hiromi, Yamamoto, Akihiko, Kamachi, Kazunari, Arakawa, Yoshichika, Kurata, Takeshi, Horiuchi, Yoshinobu

“…Haemophilus influenzae type b (Hib) is a major cause of bacterial meningitis among children. Hib conjugate vaccines have effectively prevented Hib infection,…”
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A Limulus Amoebocyte Lysate Activating Activity (LAL Activity) That Lacks Biological Activities of Endotoxin Found in Biological Products by Ochiai, Masaki, Tamura, Hiroshi, Yamamoto, Akihiko, Aizawa, Maki, Kataoka, Michiyo, Toyoizumi, Hiromi, Horiuchi, Yoshinobu

“…Pyrogenic substances in influenza HA (IHA) vaccine have been controlled by the pyrogen test or the mouse body weight decreasing toxicity (BWD) test. We…”
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Molecular design of LPS-binding peptides by Suzuki, Masatsugu Matt, Matsumoto, Megumi, Yamamoto, Akihiko, Ochiai, Masaki, Horiuchi, Yoshinobu, Niwa, Makoto, Omi, Hiroyuki, Kobayashi, Tomomi, Takagi, Takashi

“…Lipopolysaccharide (LPS), a major constituent of the outer membrane of Gram-negative bacteria, is highly toxic and can cause sepsis or septic shock. Therefore,…”
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Influenza A whole virion vaccine induces a rapid reduction of peripheral blood leukocytes via interferon-α-dependent apoptosis by Ato, Manabu, Takahashi, Yoshimasa, Fujii, Hideki, Hashimoto, Shu-ichi, Kaji, Tomohiro, Itamura, Shigeyuki, Horiuchi, Yoshinobu, Arakawa, Yoshichika, Tashiro, Masato, Takemori, Toshitada

“…Highlights ► Whole virion but not HA split influenza vaccines induce a decrease of PBL in an IFNα-dependent manner. ► TLR-7 and MyD-88 signaling is responsible…”
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Evaluation of an in vitro assay system as a potential alternative to current histamine sensitization test for acellular pertussis vaccines by Xing, Dorothy, Yuen, Chun-Ting, Asokanathan, Catpagavalli, Rigsby, Peter, Horiuchi, Yoshinobu

“…The histamine sensitization test (HIST) is a lethal test for batch release of acellular pertussis or its combination vaccines (ACV). Large numbers of animals…”
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An in vitro assay system as a potential replacement for the histamine sensitisation test for acellular pertussis based combination vaccines by Yuen, Chun-Ting, Horiuchi, Yoshinobu, Asokanathan, Catpagavalli, Cook, Sarah, Douglas-Bardsley, Alexandra, Ochiai, Masaki, Corbel, Michael, Xing, Dorothy

“…Abstract The histamine sensitisation test (HIST) for pertussis toxin is currently an official batch release test for acellular pertussis containing combination…”
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A need for careful evaluation of endotoxin contents in acellular pertussis-based combination vaccines by Kataoka, Michiyo, Ochiai, Masaki, Yamamoto, Akihiko, Horiuchi, Yoshinobu

“…Two batches each of diphtheria-tetanus-acellular pertussis vaccine (DTaP) and that combined with inactivated polio vaccine purchased from foreign markets were…”
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Influenza A whole virion vaccine induces a rapid reduction of peripheral blood leukocytes via interferon-[alpha]-dependent apoptosis by Ato, Manabu, Takahashi, Yoshimasa, Fujii, Hideki, Hashimoto, Shu-ichi, Kaji, Tomohiro, Itamura, Shigeyuki, Horiuchi, Yoshinobu, Arakawa, Yoshichika, Tashiro, Masato, Takemori, Toshitada

“…Highlights * Whole virion but not HA split influenza vaccines induce a decrease of PBL in an IFNα-dependent manner. * TLR-7 and MyD-88 signaling is responsible…”
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Investigation in a murine model of possible mechanisms of enhanced local reactions to post-primary diphtheria-tetanus toxoid boosters in recipients of acellular pertussis-diphtheria-tetanus vaccine by Ochiai, Masaki, Horiuchi, Yoshinobu, Yuen, Chun-Ting, Asokanathan, Catpagavalli, Yamamoto, Akihiko, Okada, Kenji, Kataoka, Michiyo, Markey, Kevin, Corbel, Michael, Xing, Dorothy

“…In recipients primed with acellular pertussis diphtheria-tetanus combined vaccine (DTaP) an increased incidence of severe local reactions with extensive…”
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