Search Results - "HORIKOSHI, H"
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Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
Published in The Journal of clinical investigation (15-03-1998)“…Troglitazone (CS-045) is one of the thiazolidinediones that activate the peroxisome proliferator-activated receptor gamma (PPARgamma), which is expressed…”
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Troglitazone and related compounds: Therapeutic potential beyond diabetes
Published in Life Sciences (06-10-2000)“…Troglitazone and structurally related compounds (pioglitazone, rosiglitazone etc.) containing thiazolidinediones (TZD) are a novel class of antidiabetic agents…”
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Book Review Journal Article -
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Effect of troglitazone on body fat distribution in type 2 diabetic patients
Published in Diabetes care (01-06-1999)“…Effect of troglitazone on body fat distribution in type 2 diabetic patients. Y Mori , Y Murakawa , K Okada , H Horikoshi , J Yokoyama , N Tajima and Y Ikeda…”
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Effects of angiotensin on the expression of fibrosis-associated cytokines, growth factors, and matrix proteins in human lung fibroblasts
Published in Journal of clinical pharmacy and therapeutics (01-06-2009)“…Summary Background and objectives: Angiotensin (Ang) II plays an important role in fibrogenesis in various organs, including the lung. The aim of this study…”
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389. Portal Venous Thromboses in Post-hepatectomy Patients - Successful Thrombolyses in Consecutive Two Cases
Published in European journal of surgical oncology (01-09-2012)Get full text
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Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats
Published in Diabetes (New York, N.Y.) (01-11-1988)“…Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats. T Fujiwara , S Yoshioka , T Yoshioka , I Ushiyama…”
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Binding activity of norovirus and sapovirus to histo-blood group antigens
Published in Archives of virology (01-03-2007)“…Noroviruses (NoVs) and sapoviruses (SaVs) are causative agents of human gastroenteritis. There is increasing evidence that certain human NoV strains bind to…”
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Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling
Published in The Journal of clinical investigation (15-03-1996)“…Inhibition of insulin receptor signaling by high glucose levels and by TNF-alpha was recently observed in different cell systems. The aim of the present study…”
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Leaky phenotype of X‐linked agammaglobulinaemia in a Japanese family
Published in Clinical and experimental immunology (01-06-2005)“…Summary X‐linked agammaglobulinaemia (XLA) is an inherited immunodeficiency that is caused by a block in early B‐cell differentiation. Whereas early B…”
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Molecular Design, Synthesis, and Hypoglycemic Activity of a Series of Thiazolidine-2,4-diones
Published in Journal of medicinal chemistry (10-08-2000)“…A series of imidazopyridine thiazolidine-2,4-diones were designed and synthesized from their corresponding pyridines. These compounds represent…”
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Outcomes of hepatic artery infusion therapy for hepatic metastases from colorectal carcinoma after radiological placement of infusion catheters
Published in European journal of surgical oncology (01-08-2007)“…Abstract Aim The aim of this study is to evaluate the safety and efficacy of hepatic artery infusion (HAI) of 5-fluorouracil (5FU) for patients with liver…”
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Clinical characteristics of patients with both anti-U1RNP and anti-centromere antibodies
Published in Scandinavian journal of rheumatology (01-01-2008)“…Objective: To clarify the clinical characteristics of patients having both anti-U1RNP antibodies (anti-U1RNP) and anti-centromere antibodies (ACA) in…”
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Characterization of new oral antidiabetic agent CS-045: studies in KK and ob/ob mice and Zucker fatty rats
Published in Diabetes (New York, N.Y.) (01-11-1988)“…CS-045 is a new oral antidiabetic agent that was effective in insulin-resistant diabetic animal models, including the KK mouse, the ob/ob mouse, and the Zucker…”
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Acute hyperglycemia provides an insulin-independent inducer for GLUT4 translocation in C2C12 myotubes and rat skeletal muscle
Published in Diabetes (New York, N.Y.) (01-06-1995)“…Acute hyperglycemia provides an insulin-independent inducer for GLUT4 translocation in C2C12 myotubes and rat skeletal muscle. P Galante , L Mosthaf , M…”
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Effects of troglitazone (CS-045) on insulin secretion in isolated rat pancreatic islets and HIT cells : an insulinotropic mechanism distinct from glibenclamide
Published in Diabetologia (1995)“…In order to elucidate the direct effects of (+/-)-5-[4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy) benzyl]-2,4-thiazolidinedione (Troglitazone), a…”
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EP-1056: Radiation and concurrent superselective intra-arterial cisplatin for maxillary sinus cancer
Published in Radiotherapy and oncology (01-05-2017)Get full text
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Angptl3 regulates lipid metabolism in mice
Published in Nature genetics (01-02-2002)“…The KK obese mouse is moderately obese and has abnormally high levels of plasma insulin (hyperinsulinemia), glucose (hyperglycemia) and lipids…”
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Computer-aided diagnosis system for bone scintigrams from Japanese patients: importance of training database
Published in Annals of nuclear medicine (01-10-2012)“…Aim Computer-aided diagnosis (CAD) software for bone scintigrams have recently been introduced as a clinical quality assurance tool. The purpose of this study…”
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Recovery of the vestibular function after vestibular neuronitis
Published in Acta oto-laryngologica. Supplement (1993)“…We performed steroid therapy on 34 cases with vestibular neuronitis and compared them with 77 patients not subjected to this therapy to examine the role of…”
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