Search Results - "HOOKER, J. M"

In vivo imaging of adult human hippocampal neurogenesis: progress, pitfalls and promise by Ho, N F, Hooker, J M, Sahay, A, Holt, D J, Roffman, J L

“…New neurons are produced within the hippocampus of the mammalian brain throughout life. Evidence from animal studies has suggested that the function of these…”
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A Protocol for Sedation Free MRI and PET Imaging in Adults with Autism Spectrum Disorder by Smith, C. J., Bhanot, A., Norman, E., Mullett, J. E., Bilbo, S. D., McDougle, C. J., Zürcher, N. R., Hooker, J. M.

“…Imaging technologies such as positron emission tomography (PET) and magnetic resonance imaging (MRI) present unparalleled opportunities to investigate the…”
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Noninvasive Determination of 2-[18F]-Fluoroisonicotinic Acid Hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis-Infected Mice by WEINSTEIN, E. A, LIU, L, ORDONEZ, A. A, WANG, H, HOOKER, J. M, TONGE, P. J, JAIN, S. K

“…Erratum ( vol. 57 , p. 678 ) Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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The neuroinflammatory component of negative affect in patients with chronic pain by Albrecht, D. S., Kim, M., Akeju, O., Torrado-Carvajal, A., Edwards, R. R., Zhang, Y., Bergan, C., Protsenko, E., Kucyi, A., Wasan, A. D., Hooker, J. M., Napadow, V., Loggia, M. L.

“…Negative affect (NA) is a significant cause of disability for chronic pain patients. While little is known about the mechanism underlying pain-comorbid NA,…”
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[11C]PBR28 MR–PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder by Zürcher, N. R., Loggia, M. L., Mullett, J. E., Tseng, C., Bhanot, A., Richey, L., Hightower, B. G., Wu, C., Parmar, A. J., Butterfield, R. I., Dubois, J. M., Chonde, D. B., Izquierdo-Garcia, D., Wey, H. Y., Catana, C., Hadjikhani, N., McDougle, C. J., Hooker, J. M.

“…Mechanisms of neuroimmune and mitochondrial dysfunction have been repeatedly implicated in autism spectrum disorder (ASD). To examine these mechanisms in ASD…”
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PET Imaging Demonstrates Histone Deacetylase Target Engagement and Clarifies Brain Penetrance of Known and Novel Small Molecule Inhibitors in Rat by Schroeder, F. A, Wang, C, Van de Bittner, G. C, Neelamegam, R, Takakura, W. R, Karunakaran, A, Wey, H. Y, Reis, S. A, Gale, J, Zhang, Y. L, Holson, E. B, Haggarty, S. J, Hooker, J. M

“…Histone deacetylase (HDAC) enzymes have been demonstrated as critical components in maintaining chromatin homeostasis, CNS development, and normal brain…”
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Visualizing epigenetics: Current advances and advantages in HDAC PET imaging techniques by Wang, C, Schroeder, F.A, Hooker, J.M

“…Highlights • Invasive measurements of epigenetics can be conceptually adapted for human brain imaging. • Noninvasive measurements of HDAC expression and…”
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Psychomotor Impairment Detection via Finger Interactions with a Computer Keyboard During Natural Typing by Giancardo, L., Sánchez-Ferro, A., Butterworth, I., Mendoza, C. S., Hooker, J. M.

“…Modern digital devices and appliances are capable of monitoring the timing of button presses, or finger interactions in general, with a sub-millisecond…”
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Imaging HDACs In Vivo: Cross-Validation of the [11C]Martinostat Radioligand in the Pig Brain by Donovan, L. L., Magnussen, J. H., Dyssegaard, A., Lehel, S., Hooker, J. M., Knudsen, G. M., Hansen, H. D.

“…Purpose With the emerging knowledge about the impact of epigenetic alterations on behavior and brain disorders, the ability to measure epigenetic alterations…”
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Noninvasive Determination of 2-[18F]-Fluoroisonicotinic Acid Hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis-Infected Mice by Weinstein, E. A, Liu, L, Ordonez, A. A, Wang, H, Hooker, J. M, Tonge, P. J, Jain, S. K

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The pandemic brain: Neuroinflammation in non-infected individuals during the COVID-19 pandemic by Brusaferri, Ludovica, Alshelh, Zeynab, Martins, Daniel, Kim, Minhae, Weerasekera, Akila, Housman, Hope, Morrissey, Erin J., Knight, Paulina C., Castro-Blanco, Kelly A., Albrecht, Daniel S., Tseng, Chieh-En, Zürcher, Nicole R., Ratai, Eva-Maria, Akeju, Oluwaseun, Makary, Meena M., Catana, Ciprian, Mercaldo, Nathaniel D., Hadjikhani, Nouchine, Veronese, Mattia, Turkheimer, Federico, Rosen, Bruce R., Hooker, Jacob M., Loggia, Marco L.

“…•Human study measuring pandemic-related neuroinflammation in individuals negative to COVID-19 antibodies.•Multimodal PET/MR brain imaging shows elevation in…”
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C-11 PBR28 MR-PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder by Zurcher, N. R., Loggia, M. L., Mullett, J. E., Tseng, C., Bhanot, A., Richey, L., Hightower, B. G., Wu, C., Parmar, A. J., Butterfield, R. I., Dubois, J. M., Chonde, D. B., Izquierdo-Garcia, D., Wey, H. Y., Catana, C., Hadjikhani, Nouchine, McDougle, C. J., Hooker, J. M.

“…Mechanisms of neuroimmune and mitochondrial dysfunction have been repeatedly implicated in autism spectrum disorder (ASD). To examine these mechanisms in ASD…”
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VISUALIZING EPIGENETICS: CURRENT ADVANCES AND ADVANTAGES IN HDAC PET IMAGING TECHNIQUES: Epigenetics in Brain Function by WANG, C, SCHROEDER, F. A, HOOKER, J. M

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Magnetic Resonance Contrast Agents from Viral Capsid Shells:  A Comparison of Exterior and Interior Cargo Strategies by Hooker, Jacob M, Datta, Ankona, Botta, Mauro, Raymond, Kenneth N, Francis, Matthew B

“…Two high-relaxivity nanoscale magnetic resonance contrast agents have been built using bacteriophage MS2 as a biomolecular scaffold. Protein capsid shells were…”
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Dual-Surface-Modified Bacteriophage MS2 as an Ideal Scaffold for a Viral Capsid-Based Drug Delivery System by Kovacs, Ernest W, Hooker, Jacob M, Romanini, Dante W, Holder, Patrick G, Berry, Katherine E, Francis, Matthew B

“…With the development of covalent modification strategies for viral capsids comes the ability to convert them into modular carrier systems for drug molecules…”
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Brain glial activation in fibromyalgia – A multi-site positron emission tomography investigation by Albrecht, Daniel S., Forsberg, Anton, Sandström, Angelica, Bergan, Courtney, Kadetoff, Diana, Protsenko, Ekaterina, Lampa, Jon, Lee, Yvonne C., Höglund, Caroline Olgart, Catana, Ciprian, Cervenka, Simon, Akeju, Oluwaseun, Lekander, Mats, Cohen, George, Halldin, Christer, Taylor, Norman, Kim, Minhae, Hooker, Jacob M., Edwards, Robert R., Napadow, Vitaly, Kosek, Eva, Loggia, Marco L.

“…•Fibromyalgia patients exhibit elevated cortical levels of [11C]PBR28 signal.•[11C]PBR28 signal was correlated with subjective fatigue in patients.•Results…”
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Evidence for brain glial activation in chronic pain patients by Loggia, Marco L, Chonde, Daniel B, Akeju, Oluwaseun, Arabasz, Grae, Catana, Ciprian, Edwards, Robert R, Hill, Elena, Hsu, Shirley, Izquierdo-Garcia, David, Ji, Ru-Rong, Riley, Misha, Wasan, Ajay D, Zürcher, Nicole R, Albrecht, Daniel S, Vangel, Mark G, Rosen, Bruce R, Napadow, Vitaly, Hooker, Jacob M

“…Although substantial evidence has established that microglia and astrocytes play a key role in the establishment and maintenance of persistent pain in animal…”
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Loss of protective antigen, histamine-sensitising factor and envelope polypeptides in cultural variants of Bordetella pertussis by WARDLAW, A. C, PARTON, R, HOOKER, MARGARET J

“…Department of Microbiology, Glasgow University, Alexander Stone Building, Garsacube Estate, Bearsden, Glasgow Received June 20, 1975 Accepted September 16,…”
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The development of complement-fixing antibody in horses after infection with Mycoplasma equirhinis by Hooker, J M, Butler, M

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Neuroinflammatory component of gray matter pathology in multiple sclerosis by Herranz, Elena, Giannì, Costanza, Louapre, Céline, Treaba, Constantina A., Govindarajan, Sindhuja T., Ouellette, Russell, Loggia, Marco L., Sloane, Jacob A., Madigan, Nancy, Izquierdo-Garcia, David, Ward, Noreen, Mangeat, Gabriel, Granberg, Tobias, Klawiter, Eric C., Catana, Ciprian, Hooker, Jacob M., Taylor, Norman, Ionete, Carolina, Kinkel, Revere P., Mainero, Caterina

“…Objective In multiple sclerosis (MS), using simultaneous magnetic resonance–positron emission tomography (MR‐PET) imaging with 11C‐PBR28, we quantified…”
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