Search Results - "HONOUR, J.W."

Reduced maternal dexamethasone dosage for the prenatal treatment of congenital adrenal hyperplasia by Coleman, M.A., Honour, J.W.

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Effect of red clover-derived isoflavone supplementation on insulin-like growth factor, lipid and antioxidant status in healthy female volunteers: a pilot study by Campbell, M.J, Woodside, J.V, Honour, J.W, Morton, M.S, Leathem, A.J.C

“…Background: Isoflavones are estrogen-like plant compounds that may protect against cardiovascular disease and endocrine-responsive cancer. Isoflavones may,…”
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Urinary steroid profile analysis by Honour, J.W

“…Background: A detailed analysis (profile) of the steroid metabolites in urine is useful for diagnosis of adrenal problems. Hospitals from many of UK health…”
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Metabolism of fetal and neonatal adrenal steroids by Shackleton, C H, Honour, J W, Taylor, N F

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Short-term phytoestrogen supplementation alters insulin-like growth factor profile but not lipid or antioxidant status by Woodside, Jayne V., Campbell, Maeli J., Denholm, Erica E., Newton, Lynne, Honour, John W., Morton, Michael S., Young, Ian S., Leathem, Anthony J.C.

“…Phytoestrogens are plant compounds that have been proposed to have a variety of health benefits. The aim of this study was to assess the effects of these…”
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Reduced maternal dexamethasone dosage for the prenatal treatment of congenital adrenal hyperplasia by Coleman, M.A., Honour, J.W.

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Inhaled corticosteroids and the hypothalamic–pituitary–adrenal (HPA) axis: do we understand their interaction? by DEKHUIJZEN, P.N.R., HONOUR, J.W.

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Hypothalamic-pituitary-adrenal axis by Honour, J W

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Plasma cortisol, cortisone and urinary glucocorticoid metabolites in preterm infants by Midgley, P C, Holownia, P, Smith, J, Moore, M, Russell, K, Oates, N, Shaw, J C, Honour, J W

“…In the fetal circulation, there is a low cortisol:cortisone (F:E) ratio ( approximately 0.3) suggesting high activity of 11beta-hydroxysteroid dehydrogenase…”
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17-Hydroxylase/17,20 lyase deficiency diagnosed during childhood by Wolthers, O D, Rumsby, G, Techatraisak, K, Honour, J W, Hindmarsh, P C

“…We present a case of familial 17alpha-hydroxylase/17,20 lyase (CYP17) deficiency in which the index case, a 14-year-old XX girl, led to the diagnosis of the…”
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Adrenal function in asthma by Priftis, K, Milner, A D, Conway, E, Honour, J W

“…A dose dependent suppression of daily cortisol excretion was shown in 25 children with asthma being treated with beclomethasone dipropionate. Cortisol…”
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Treatment with flutamide decreases cortisol clearance: implications for therapy in congenital adrenal hyperplasia by Charmandari, E, Johnston, A, Honour, J W, Brook, C G D, Hindmarsh, P C

“…Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is characterized by a defect in cortisol and often aldosterone secretion, and adrenal…”
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Problems in diagnosis and management of congenital adrenal hyperplasia due to 21-hydroxylase deficiency by Honour, J W, Rumsby, G

“…A number of biochemical tests have been utilized to assist the diagnosis of steroid 21-hydroxylase deficiency. The specificity and accuracy of plasma…”
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Genetic analysis of the steroid 21-hydroxylase gene following in vitro amplification of genomic DNA by Rumsby, G, Skinner, C, Honour, J W

“…The 5' end of the steroid 21-hydroxylase B gene encompassing putative control regions and the first 3 exons, has been selectively amplified in vitro from a…”
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The determination of 11 beta-hydroxyandrostenedione in human follicular fluid and plasma by Holownia, P, Owen, E J, Hampl, R, Jacobs, H S, Honour, J W

“…The development of a chromatographic/immunoassay method is presented for the measurement of 11 beta-hydroxyandrostenedione (11 beta-OH-A4) in ovarian…”
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Synthesis of [11,11,12,12-2H4]progesterone for mass spectral investigations of peripheral metabolism by Kirk, D N, Smith, C Z, Honour, J W

“…Hecogenin has been transformed into [11,11,12,12-2H4]progesterone via base-catalyzed isotope exchange with D2O (at C-11), carbenic decomposition of the…”
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Analysis of intact steroid conjugates by secondary ion mass spectrometry (including FABMS) and by gas chromatography by Shackleton, C H, Mattox, V R, Honour, J W

“…The analysis of intact steroid conjugates by two different methods is described. One method employed secondary ion mass spectrometry (SIMS) using a Cs+ beam…”
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Analysis of steroids in urine for differentiation of pseudohypoaldosteronism and aldosterone biosynthetic defect by Honour, J W, Dillon, M J, Shackleton, C H

“…The salt-losing syndromes in the neonatal period and early infancy due to adrenal disease can be differentiated by the pattern of excretion of steroids in…”
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Pseudohypoaldosteronism: severe salt wasting in infancy caused by generalized mineralocorticoid unresponsiveness by Savage, M O, Jefferson, I G, Dillon, M J, Milla, P J, Honour, J W, Grant, D B

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Intermediates in 16-androstene biosynthesis in neonatal porcine testis by Kwan, T.K., Honour, J.W., Gower, D.B.

“…The metabolism of pregnenolone has been studied in microsomal preparations of testes from 3-week old piglets. Metabolites identified after derivatization by…”
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