Search Results - "HONGZU REN"

Hepatic xenobiotic metabolizing enzyme and transporter gene expression through the life stages of the mouse by Lee, Janice S, Ward, William O, Liu, Jie, Ren, Hongzu, Vallanat, Beena, Delker, Don, Corton, J Christopher

“…Differences in responses to environmental chemicals and drugs between life stages are likely due in part to differences in the expression of xenobiotic…”
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Engineering human cell spheroids to model embryonic tissue fusion in vitro by Belair, David G, Wolf, Cynthia J, Wood, Carmen, Ren, Hongzu, Grindstaff, Rachel, Padgett, William, Swank, Adam, MacMillan, Denise, Fisher, Anna, Winnik, Witold, Abbott, Barbara D

“…Epithelial-mesenchymal interactions drive embryonic fusion events during development, and perturbations of these interactions can result in birth defects…”
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Ozone-induced fetal growth restriction in rats is associated with sexually dimorphic placental and fetal metabolic adaptation by Miller, Colette N., Dye, Janice A., Henriquez, Andres R., Stewart, Erica J., Lavrich, Katelyn S., Carswell, Gleta K., Ren, Hongzu, Freeborn, Danielle L., Snow, Samantha J., Schladweiler, Mette C., Richards, Judy H., Kodavanti, Prasada R.S., Fisher, Anna, Chorley, Brian N., Kodavanti, Urmila P.

“…The importance of the placenta in mediating the pre- and post-natal consequences of fetal growth restriction has been increasingly recognized. However, the…”
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Transcriptional ontogeny of the developing liver by Lee, Janice S, Ward, William O, Knapp, Geremy, Ren, Hongzu, Vallanat, Beena, Abbott, Barbara, Ho, Karen, Karp, Seth J, Corton, J Christopher

“…During embryogenesis the liver is derived from endodermal cells lining the digestive tract. These endodermal progenitor cells contribute to forming the…”
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Meta-analysis of gene expression in the mouse liver reveals biomarkers associated with inflammation increased early during aging by Lee, Janice S., Ward, William O., Ren, Hongzu, Vallanat, Beena, Darlington, Gretchen J., Han, Eun-Soo, Laguna, Juan C., DeFord, James H., Papaconstantinou, John, Selman, Colin, Corton, J. Christopher

“…► A meta-analysis was conducted on aging mouse liver gene expression profiles. ► Little overlap across studies in number of genes or canonical pathways…”
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Genome-wide analysis of BEAS-2B cells exposed to trivalent arsenicals and dimethylthioarsinic acid by Chilakapati, Jaya, Wallace, Kathleen, Ren, Hongzu, Fricke, Michael, Bailey, Kathryn, Ward, William, Creed, Jack, Kitchin, Kirk

“…Abstract Lung is a major target for arsenic carcinogenesis in humans by both oral and inhalation routes. However, the carcinogenic mode of action of arsenicals…”
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Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides by Tully, Douglas B., Bao, Wenjun, Goetz, Amber K., Blystone, Chad R., Ren, Hongzu, Schmid, Judith E., Strader, Lillian F., Wood, Carmen R., Best, Deborah S., Narotsky, Michael G., Wolf, Douglas C., Rockett, John C., Dix, David J.

“…Four triazole fungicides were studied using toxicogenomic techniques to identify potential mechanisms of action. Adult male Sprague-Dawley rats were dosed for…”
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Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) by Vallanat, Beena, Anderson, Steven P, Brown-Borg, Holly M, Ren, Hongzu, Kersten, Sander, Jonnalagadda, Sudhakar, Srinivasan, Rajagopalan, Corton, J Christopher

“…The nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) regulates responses to chemical or physical stress in part by altering…”
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Pharmacokinetic and Genomic Effects of Arsenite in Drinking Water on Mouse Lung in a 30-Day Exposure by Chilakapati, Jaya, Wallace, Kathleen, Hernandez-Zavala, Araceli, Moore, Tanya, Ren, Hongzu, Kitchin, Kirk T.

“…The 2 objectives of this subchronic study were to determine the arsenite drinking water exposure dependent increases in female C3H mouse liver and lung tissue…”
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Inhibition of Polyglutamine Protein Aggregation and Cell Death by Novel Peptides Identified by Phage Display Screening by Nagai, Yoshitaka, Tucker, Timothy, Ren, Hongzu, Kenan, Daniel J., Henderson, Barry S., Keene, Jack D., Strittmatter, Warren J., Burke, James R.

“…Proteins with expanded polyglutamine domains cause eight inherited neurodegenerative diseases, including Huntington's, but the molecular mechanism(s)…”
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Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides by Goetz, Amber K., Bao, Wenjun, Ren, Hongzu, Schmid, Judith E., Tully, Douglas B., Wood, Carmen, Rockett, John C., Narotsky, Michael G., Sun, Guobin, Lambert, Guy R., Thai, Sheau-Fung, Wolf, Douglas C., Nesnow, Stephen, Dix, David J.

“…Four triazole fungicides used in agricultural or pharmaceutical applications were examined for hepatotoxic effects in mouse liver. Besides organ weight,…”
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Effect of conazole fungicides on reproductive development in the female rat by Rockett, John C., Narotsky, Michael G., Thompson, Kary E., Thillainadarajah, Inthirany, Blystone, Chad R., Goetz, Amber K., Ren, Hongzu, Best, Deborah S., Murrell, Rachel N., Nichols, Harriette P., Schmid, Judith E., Wolf, Douglas C., Dix, David J.

“…Three triazole fungicides were evaluated for effects on female rat reproductive development. Rats were exposed via feed to propiconazole (P) (100, 500, or 2500…”
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Transcriptional changes associated with reduced spontaneous liver tumor incidence in mice chronically exposed to high dose arsenic by Nelson, Gail M, Ahlborn, Gene J, Allen, James W, Ren, Hongzu, Corton, J. Christopher, Waalkes, Michael P, Kitchin, Kirk T, Diwan, Bhalchandra A, Knapp, Geremy, Delker, Don A

“…Abstract Exposure of male C3H mice in utero (from gestational days 8–18) to 85 ppm sodium arsenite via the dams’ drinking water has previously been shown to…”
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Regulation of Proteome Maintenance Gene Expression by Activators of Peroxisome Proliferator-Activated Receptor α by Ren, Hongzu, Vallanat, Beena, Brown-Borg, Holly M., Currie, Richard, Corton, J. Christopher

“…The nuclear receptor peroxisome proliferator-activated receptor α (PPARα) is activated by a large number of xenobiotic and hypolipidemic compounds called…”
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Dexamethasone stimulates human A1 adenosine receptor (A1AR) gene expression through multiple regulatory sites in promoter B by Ren, H, Stiles, G L

“…The expression of the human A1 adenosine receptor gene is controlled by two promoters, promoters A and B, and they are located 600 base pairs apart. The…”
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A database for tracking toxicogenomic samples and procedures by Bao, Wenjun, Schmid, Judith E., Goetz, Amber K., Ren, Hongzu, Dix, David J.

“…Reproductive toxicogenomic studies generate large amounts of toxicological and genomic data. On the toxicology side, a substantial quantity of data accumulates…”
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Determinants of gene expression in the human liver: Impact of aging and sex on xenobiotic metabolism by Corton, J. Christopher, Lee, Janice S., Liu, Jie, Ren, Hongzu, Vallanat, Beena, DeVito, Michael

“…There is a need to characterize the potential susceptibility of older adults to toxicity from environmental chemical exposures. Liver xenobiotic metabolizing…”
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Cloning, expression, and characterization of the unique bovine A1 adenosine receptor. Studies on the ligand binding site by site-directed mutagenesis by OLAH, M. E, HONGZU REN, OSTROWSKI, J, JACOBSON, K. A, STILES, G. L

“…The bovine brain A1 adenosine receptor (A1AR) is distinct from other A1ARs in that it displays the unique agonist potency series of…”
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Characterization of the human A1 adenosine receptor gene. Evidence for alternative splicing by Ren, H, Stiles, G L

“…To approach transcriptional and translational regulation of adenosine receptors, we have isolated cDNA and genomic clones of the human A1 adenosine receptor…”
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Ozone-Induced Dysregulation of Neuroendocrine Axes Requires Adrenal-Derived Stress Hormones by Henriquez, Andres R, House, John S, Snow, Samantha J, Miller, Colette N, Schladweiler, Mette C, Fisher, Anna, Ren, Hongzu, Valdez, Matthew, Kodavanti, Prasada R, Kodavanti, Urmila P

“…Acute ozone inhalation increases circulating stress hormones through activation of the sympathetic-adrenal-medullary and hypothalamic-pituitary-adrenal axes…”
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