Search Results - "HONGYING ZHANG"

CCND1 silencing suppresses liver cancer stem cell differentiation through inhibiting autophagy by Zhang, Hongying

“…Liver cancer stem cells (LCSCs) are responsible for the carcinogenesis, recurrence, metastasis and chemoresistance of hepatocellular carcinoma (HCC). This…”
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Ferroptosis in the tumor microenvironment: perspectives for immunotherapy by Xu, Huanji, Ye, Di, Ren, Meiling, Zhang, Hongying, Bi, Feng

“…Targeting ferroptosis, which provokes lipid peroxidation in cancer cells, presents potentially new avenues for anticancer therapy. Recent studies have begun to…”
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Targeting mTOR for cancer therapy by Hua, Hui, Kong, Qingbin, Zhang, Hongying, Wang, Jiao, Luo, Ting, Jiang, Yangfu

“…Mechanistic target of rapamycin (mTOR) is a protein kinase regulating cell growth, survival, metabolism, and immunity. mTOR is usually assembled into several…”
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Complex roles of cAMP–PKA–CREB signaling in cancer by Zhang, Hongying, Kong, Qingbin, Wang, Jiao, Jiang, Yangfu, Hua, Hui

“…Abstract Cyclic adenosine monophosphate (cAMP) is the first discovered second messenger, which plays pivotal roles in cell signaling, and regulates many…”
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Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy by Jiang, Yangfu, Zhang, Hongying, Wang, Jiao, Liu, Yongliang, Luo, Ting, Hua, Hui

“…Cancer microenvironment is critical for tumorigenesis and cancer progression. The extracellular matrix (ECM) interacts with tumor and stromal cells to promote…”
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Targeting Akt in cancer for precision therapy by Hua, Hui, Zhang, Hongying, Chen, Jingzhu, Wang, Jiao, Liu, Jieya, Jiang, Yangfu

“…Abstract Biomarkers-guided precision therapeutics has revolutionized the clinical development and administration of molecular-targeted anticancer agents…”
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Mechanisms for estrogen receptor expression in human cancer by Hua, Hui, Zhang, Hongying, Kong, Qingbin, Jiang, Yangfu

“…Estrogen is a steroid hormone that has critical roles in reproductive development, bone homeostasis, cardiovascular remodeling and brain functions. However,…”
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CCND1 silencing suppresses liver cancer stem cell differentiation and overcomes 5-Fluorouracil resistance in hepatocellular carcinoma by Ding, Hao, Wang, Yijun, Zhang, Hongying

“…Chemoresistance is one of the major barriers in chemotherapy-based hepatocellular carcinoma (HCC) intervention. 5-Fluorouracil (5-Fu) is a widely used as an…”
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Complex roles of the old drug aspirin in cancer chemoprevention and therapy by Hua, Hui, Zhang, Hongying, Kong, Qingbin, Wang, Jiao, Jiang, Yangfu

“…The nonsteroidal anti‐inflammatory agent aspirin is widely used for preventing and treating cardiovascular and cerebrovascular diseases. In addition,…”
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TaNAC2, a NAC-type wheat transcription factor conferring enhanced multiple abiotic stress tolerances in Arabidopsis by Mao, Xinguo, Zhang, Hongying, Qian, Xueya, Li, Ang, Zhao, Guangyao, Jing, Ruilian

“…Environmental stresses such as drought, salinity, and cold are major factors that significantly limit agricultural productivity. NAC transcription factors play…”
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Overexpression of a common wheat gene TaSnRK2.8 enhances tolerance to drought, salt and low temperature in Arabidopsis by Zhang, Hongying, Mao, Xinguo, Wang, Chengshe, Jing, Ruilian

“…Drought, salinity and low temperatures are major factors limiting crop productivity and quality. Sucrose non-fermenting1-related protein kinase 2 (SnRK2) plays…”
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Single-shot BOTDA based on an optical chirp chain probe wave for distributed ultrafast measurement by Zhou, Dengwang, Dong, Yongkang, Wang, Benzhang, Pang, Chao, Ba, Dexin, Zhang, Hongying, Lu, Zhiwei, Li, Hui, Bao, Xiaoyi

“…Brillouin optical time-domain analysis (BOTDA) requires frequency mapping of the Brillouin spectrum to obtain environmental information (e.g., temperature or…”
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Increasing concurrent exposure of global breadbaskets to reproductive heat extremes by Zhang, Hongying, Yu, Xiaoge, Qiao, Fengxue, Li, Chao

“…Abstract In recent years, circumglobal heatwaves are becoming increasingly frequent, motivating concerns about the concurrent exposure of global breadbaskets…”
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TaSnRK2.4, an SNF1-type serine/threonine protein kinase of wheat (Triticum aestivum L.), confers enhanced multistress tolerance in Arabidopsis by Mao, Xinguo, Zhang, Hongying, Tian, Shanjun, Chang, Xiaoping, Jing, Ruilian

“…Osmotic stresses such as drought, salinity, and cold are major environmental factors that limit agricultural productivity worldwide. Protein…”
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Topology Optimized Multimaterial Soft Fingers for Applications on Grippers, Rehabilitation, and Artificial Hands by Zhang, Hongying, Kumar, A. Senthil, Chen, Feifei, Fuh, Jerry Y. H., Wang, Michael Yu

“…Multimaterial soft robots, composing of integrated soft actuators and a relatively harder body, show great potential to exert higher payloads and support their…”
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Exploiting RIG-I-like receptor pathway for cancer immunotherapy by Jiang, Yangfu, Zhang, Hongying, Wang, Jiao, Chen, Jinzhu, Guo, Zeyu, Liu, Yongliang, Hua, Hui

“…RIG-I-like receptors (RLRs) are intracellular pattern recognition receptors that detect viral or bacterial infection and induce host innate immune responses…”
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Slope-assisted BOTDA based on vector SBS and frequency-agile technique for wide-strain-range dynamic measurements by Zhou, Dengwang, Dong, Yongkang, Wang, Benzhang, Jiang, Taofei, Ba, Dexin, Xu, Pengbai, Zhang, Hongying, Lu, Zhiwei, Li, Hui

“…We present a slope-assisted BOTDA system based on the vector stimulated Brillouin scattering (SBS) and frequency-agile technique (FAT) for the…”
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MiR-188-5p inhibits cell proliferation and migration in ovarian cancer via competing for CCND2 with ELAVL1 by Hongying Zhang, Ningxia Yuan, Hongcai Che, Xifeng Cheng

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Distributed Airflow Sensing Based on High-Spatial-Resolution BOTDA and a Self-Heated High-Attenuation Fiber by Zhang, Hongying, Lei, Yanyang, Zhou, Jinzhe, Dong, Yongkang

“…An all-fiber distributed airflow sensing method based on a differential pulse-width pair Brillouin optical time domain analysis (DPP-BOTDA) and a self-heated…”
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Exploring the impact of innovation guidance on user participation in online communities: A mixed methods investigation of cognitive and affective perspectives by Li, Yang, Gou, Xiaona, Hu, Haiqing, Zhang, Hongying

“…In recent years, many online communities have launched opinion-gathering activities to promote user participation in innovation and improve the quality of new…”
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