Search Results - "HONG, Jean S."

2-Amino-6-arylsulfonylbenzonitriles as Non-nucleoside Reverse Transcriptase Inhibitors of HIV-1 by Chan, Joseph H, Hong, Jean S, Hunter, Robert N, Orr, G. Faye, Cowan, Jill R, Sherman, Douglas B, Sparks, Steven M, Reitter, Barbara E, Andrews, C. Webster, Hazen, Richard J, St Clair, Marty, Boone, Lawrence R, Ferris, Rob G, Creech, Katrina L, Roberts, Grace B, Short, Steven A, Weaver, Kurt, Ott, Ronda J, Ren, Jingshan, Hopkins, Andrew, Stuart, David I, Stammers, David K

“…A series of 2-amino-5-arylthiobenzonitriles (1) was found to be active against HIV-1. Structural modifications led to the sulfoxides (2) and sulfones (3). The…”
Get full text

X-ray Crystal Structures of Candida albicans Dihydrofolate Reductase:  High Resolution Ternary Complexes in Which the Dihydronicotinamide Moiety of NADPH Is Displaced by an Inhibitor by WHITLOW, Marc, HOWARD, Andrew J., STEWART, David, HARDMAN, Karl D., CHAN, Joseph H., BACCANARI, David P., TANSIK, Robert L., HONG, Jean S., KUYPER, Lee F.

“…X-ray crystallographic analysis of 5-(4'-substituted phenyl)sulfanyl-2,4-diaminoquinazoline inhibitors in ternary complex with Candida albicans dihydrofolate…”
Get full text

Selective Inhibitors of Candida albicans Dihydrofolate Reductase: Activity and Selectivity of 5-(Arylthio)-2,4-diaminoquinazolines by Chan, Joseph H, Hong, Jean S, Kuyper, Lee F, Baccanari, David P, Joyner, Suzanne S, Tansik, Robert L, Boytos, Christine M, Rudolph, Sharon K

“…The recent increase in fungal infections, especially among AIDS patients, has resulted in the need for more effective antifungal agents. In our search for such…”
Get full text

X-ray Crystal Structures of Candida a lbicans Dihydrofolate Reductase:  High Resolution Ternary Complexes in Which the Dihydronicotinamide Moiety of NADPH Is Displaced by an Inhibitor by Whitlow, Marc, Howard, Andrew J, Stewart, David, Hardman, Karl D, Chan, Joseph H, Baccanari, David P, Tansik, Robert L, Hong, Jean S, Kuyper, Lee F

“…X-ray crystallographic analysis of 5-(4‘-substituted phenyl)sulfanyl-2,4-diaminoquinazoline inhibitors in ternary complex with Candida albicans dihydrofolate…”
Get full text

Antiradiation agents. Substituted 2-pyridyloxy and 2-quinolyloxy derivatives of S-2-(alkylamino)ethyl hydrogen thiosulfates and 3-alkylthiazolidines and substituted 2-pyridyloxy derivatives of 2-(alkylamino)ethanethiols and corresponding disulfides by Westland, Roger D, Cooley, Richard A, Holmes, Joyce L, Hong, Jean S, Lin, May H, Zwiesler, Martin L

Get full text

Effect of the sulfur-covering group on the antiradiation activity of substituted 2-aminoethanethiols by Westland, Roger D, Mouk, Mary L, Holmes, Joyce L, Cooley, Richard A, Hong, Jean S, Grenan, Marie M

Get full text

Synthesis of 1,3-diamino-7,8,9,10-tetrahydropyrido[3,2-f]-quinazolines. Inhibitors of Candida albicans dihydrofolate reductase as potential antifungal agents by Chan, Joseph H., Baccanari, David P., Tansik, Robert L., Boytos, Christine M., Rudolph, Sharon K., Brown, Andrew D., Hong, Jean S., Kuyper, Lee F., Jones, Michael L.

“…A series of novel 1,3‐diamino‐7,8,9,10‐tetrahydropyrido[3,2‐f]quinazolines were synthesized starting from 6‐amino‐5‐cyanoquinoline (4). These compounds…”
Get full text