Search Results - "HOMBURGER, H. A."

Combination testing for antibodies in the diagnosis of coeliac disease: comparison of multiplex immunoassay and ELISA methods by RASHTAK, S., ETTORE, M. W., HOMBURGER, H. A., MURRAY, J. A.

“…Summary Background  Tissue transglutaminase (TTG) antibodies and newly developed deamidated gliadin peptide (DGP) antibodies have better accuracy than native…”
Get full text

The diagnosis and incidence of allergic fungal sinusitis by Ponikau, J U, Sherris, D A, Kern, E B, Homburger, H A, Frigas, E, Gaffey, T A, Roberts, G D

“…To reevaluate the current criteria for diagnosing allergic fungal sinusitis (AFS) and determine the incidence of AFS in patients with chronic rhinosinusitis…”
Get more information

Quantitative IgE antibody assays in allergic diseases by Yunginger, John W., Ahlstedt, Staffan, Eggleston, Peyton A., Homburger, Henry A., Nelson, Harold S., Ownby, Dennis R., Platts-Mills, Thomas A.E., Sampson, Hugh A., Sicherer, Scott H., Weinstein, Allan M., Williams, P.Brock, Wood, Robert A., Zeiger, Robert S.

“…During the past several years, immunoassays for specific IgE antibodies have been refined to permit reporting results in mass units. Thus quantitative…”
Get full text

Agreement of anti‐neutrophil cytoplasmic antibody measurements obtained from serum and plasma by Lee, A. S., Finkielman, J. D., Peikert, T., Hummel, A. M., Viss, M. A., Jacob, G. L., Homburger, H. A., Specks, U.

“…Summary Serum and plasma are used interchangeably to measure anti‐neutrophil cytoplasmic antibodies (ANCA), even though the release of ANCA target antigens…”
Get full text

Peripheral neuropathy associated with sicca complex by GRANT, I. A, HUNDER, G. G, HOMBURGER, H. A, DYCK, P. J

“…Peripheral neuropathy occurs in Sjögren's syndrome, a disorder in which systemic immunologic phenomena, including vasculitis, are common. Neuropathy also…”
Get full text

Frequency and significance of antibodies to liver/kidney microsome type 1 in adults with chronic active hepatitis by Czaja, A J, Manns, M P, Homburger, H A

“…To assess the frequency of antibodies to liver/kidney microsome type 1 (anti-LKM1) in patients with chronic active hepatitis, 131 such patients were tested by…”
Get more information

Quantitative measurement of autoantibodies to recombinant mitochondrial antigens in patients with primary biliary cirrhosis: Relationship of levels of autoantibodies to disease progression by Van Norstrand, Michael D., Malinchoc, Michael, Lindor, K. D., Therneau, T. M., Gershwin, M. E., Leung, P. S., Dickson, E. R., Homburger, H. A.

“…We examined the clinical usefulness of measurements of antimitochondrial autoantibodies (AMA) in predicting disease progression in patients with primary…”
Get full text

A proportion of proteinase 3 (PR3)‐specific anti‐neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N‐terminal activation dipeptide by SUN, J, FASS, D. N, VISS, M. A, HUMMEL, A. M, TANG, H, HOMBURGER, H. A, SPECKS, U

“…ANCA directed against PR3 are highly specific for Wegener's granulomatosis and microscopic polyangiitis, and have been implicated in the pathogenesis of small…”
Get full text

Human mast cells expressing recombinant proteinase 3 (PR3) as substrate for clinical testing for anti‐neutrophil cytoplasmic antibodies (ANCA) by SPECKS, U., WIEGERT, E. M., HOMBURGER, H. A.

“…We have expressed conformationally intact, enzymatically active recombinant PR3 in HMC‐1 cells (HMC‐1/PR3 cells) that is recognized by C‐ANCA. Here we directly…”
Get full text

Detection of antinuclear antibodies: comparative evaluation of enzyme immunoassay and indirect immunofluorescence methods by Homburger, H A, Cahen, Y D, Griffiths, J, Jacob, G L

“…To evaluate a commercial microtiter enzyme immunoassay for antinuclear antibodies (ANA) by comparing the results of tests performed with this assay to an…”
Get more information

Does antimitochondrial antibody status affect response to treatment in patients with primary biliary cirrhosis? Outcomes of ursodeoxycholic acid therapy and liver transplantation by Kim, W R, Poterucha, J J, Jorgensen, R A, Batts, K P, Homburger, H A, Dickson, E R, Krom, R A, Wiesner, R H, Lindor, K D

“…Approximately 5% to 10% of patients with features otherwise consistent with primary biliary cirrhosis (PBC) lack antimitochondrial antibodies (AMA). Most of…”
Get full text

Capture-ELISA based on recombinant PR3 is sensitive for PR3–ANCA testing and allows detection of PR3 and PR3–ANCA/PR3 immunecomplexes by Sun, Jiayan, Fass, David N, Hudson, Jay A, Viss, Margaret A, Wieslander, Jörgen, Homburger, Henry A, Specks, Ulrich

“…Proteinase 3 (PR3), a constituent of azurophil granules of neutrophils (polymorphonuclear cells, PMNs), is the target antigen for most anti-neutrophil…”
Get full text

Persistent problems with standardization of immunoassays for anti-cardiolipin antibodies by Fontaine, M, Homburger, H A, Nichols, W L

Get more information

The nature and prognosis of severe cryptogenic chronic active hepatitis by Czaja, A J, Carpenter, H A, Santrach, P J, Moore, S B, Homburger, H A

“…Cryptogenic chronic active hepatitis may be an autoimmune or viral disease. Our aims were to determine the clinical features, human leukocyte antigen…”
Get more information

Immunoelectron microscopic investigation of creatine kinase BB-isoenzyme after cerebral ischemia in gerbils by TOMIMOTO, H, YAMAMOTO, K, HOMBURGER, H. A, YANAGIHARA, T

“…Alteration of creatine kinase BB-isoenzyme (CK-BB) was investigated in the vulnerable CA1 region of the hippocampus of ischemic and postischemic gerbil brains…”
Get full text

Immunohistochemical characterization of hepatic lymphocytes in primary biliary cirrhosis in comparison with primary sclerosing cholangitis and autoimmune chronic active hepatitis by Hashimoto, E, Lindor, K D, Homburger, H A, Dickson, E R, Czaja, A J, Wiesner, R H, Ludwig, J

“…We analyzed the immunophenotypes of hepatic cellular infiltrates by quantitative immunohistochemical methods in biopsy specimens from 20 patients with primary…”
Get more information

Evidence against hepatitis viruses as important causes of severe autoimmune hepatitis in the United States by Czaja, A J, Carpenter, H A, Santrach, P J, Moore, S B, Taswell, H F, Homburger, H A

“…To determine if the hepatitis viruses are important etiologic factors in autoimmune hepatitis, the clinical, immunoserologic, virologic and HLA phenotypes of…”
Get more information

A Controlled Trial of Cyclosporine in the Treatment of Primary Biliary Cirrhosis by Wiesner, Russell H, Ludwig, Jurgen, Lindor, Keith D, Jorgensen, Roberta A, Baldus, William P, Homburger, Henry A, Dickson, E. Rolland

“…Primary biliary cirrhosis is a progressive disease of the liver characterized by the immunologic destruction of bile ducts; effective therapy is lacking. We…”
Get full text

Autoantibodies in liver disease by Czaja, Albert J., Homburger, Henry A.

Get full text

Complement activation during cardiopulmonary bypass. Comparison of bubble and membrane oxygenators by Cavarocchi, N C, Pluth, J R, Schaff, H V, Orszulak, T A, Homburger, H A, Solis, E, Kaye, M P, Clancy, M S, Kolff, J, Deeb, G M

“…A prospective randomized trial involving 91 patients undergoing cardiopulmonary bypass compared the effects of bubble oxygenators (with and without…”
Get more information