Search Results - "HOM, Gary"

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase by MacMicking, John D., Nathan, Carl, Hom, Gary, Chartrain, Nicole, Fletcher, Daniel S., Trumbauer, Myrna, Stevens, Karla, Xie, Qiao-wen, Sokol, Karen, Hutchinson, Nancy, Chen, Howard, Mudget, John S.

“…Mice deficient in inducible nitric oxide synthase (iNOS) were generated to test the idea that !NOS defends the host against infectious agents and tumor cells…”
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Human β3-Adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides by BROCKUNIER, Linda L, PARMEE, Emma R, MACINTYRE, D. Euan, TOTA, Laurie, WYVRATT, Matthew J, FISHER, Michael H, WEBER, Ann E, OK, Hyun O, CANDELORE, Mari R, CASCIERI, Margaret A, COLWELL, Lawrence F, LIPING DENG, FEENEY, William P, FORREST, Michael J, HOM, Gary J

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Activation of melanocortin MC4 receptors increases erectile activity in rats ex copula by Martin, William J, McGowan, Erin, Cashen, Doreen E, Gantert, Liza T, Drisko, Jennifer E, Hom, Gary J, Nargund, Ravi, Sebhat, Iyassu, Howard, Andrew D, Van der Ploeg, Lex H.T, MacIntyre, D.Euan

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Design and Pharmacology of N-[(3R)-1,2,3,4-Tetrahydroisoquinolinium- 3-ylcarbonyl]-(1R)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1H-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (1), a Potent, Selective, Melanocortin Subtype-4 Receptor Agonist by Sebhat, Iyassu K, Martin, William J, Ye, Zhixiong, Barakat, Khaled, Mosley, Ralph T, Johnston, David B. R, Bakshi, Raman, Palucki, Brenda, Weinberg, David H, MacNeil, Tanya, Kalyani, Rubana N, Tang, Rui, Stearns, Ralph A, Miller, Randy R, Tamvakopoulos, Constantin, Strack, Alison M, McGowan, Erin, Cashen, Doreen E, Drisko, Jennifer E, Hom, Gary J, Howard, Andrew D, MacIntyre, D. Euan, van der Ploeg, Lex H. T, Patchett, Arthur A, Nargund, Ravi P

“…Synthetic and natural peptides that act as nonselective melanocortin receptor agonists have been found to be anorexigenic and to stimulate erectile activity…”
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Discovery of a Potent, Orally Bioavailable β3 Adrenergic Receptor Agonist, (R)-N-[4-[2-[[2-Hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4-[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide by Mathvink, Robert J, Tolman, J. Samuel, Chitty, Dawn, Candelore, Mari R, Cascieri, Margaret A, Colwell, Lawrence F, Deng, Liping, Feeney, William P, Forrest, Michael J, Hom, Gary J, MacIntyre, D. Euan, Miller, Randall R, Stearns, Ralph A, Tota, Laurie, Wyvratt, Matthew J, Fisher, Michael H, Weber, Ann E

“…As part of our investigation into the development of orally bioavailable β3 adrenergic receptor agonists, we have identified a series of pyridylethanolamine…”
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Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective β3 adrenergic receptor agonist antiobesity agents by BIFTU, T, FENG, D. D, FORREST, M. J, HOM, G. J, MACLNTYRE, D. E, STEARNS, R. A, STRADER, C. D, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, LIANG, G.-B, KUO, H, XIAOXIA QIAN, NAYLOR, E. M, COLANDREA, V. J, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F

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Discovery of an orally bioavailable alkyl oxadiazole β3 adrenergic receptor agonist by FENG, D. D, BIFTU, T, MILLER, R. R, STEARNS, R. A, STRADER, C. D, TOTA, L, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F, LIPING DENG, FEENEY, W. P, FORREST, M. J, HOM, G. J, MACLNTYRE, D. E

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A 28 Gb/s 560 mW Multi-Standard SerDes With Single-Stage Analog Front-End and 14-Tap Decision Feedback Equalizer in 28 nm CMOS by Kimura, Hiroshi, Aziz, Pervez M., Tai Jing, Sinha, Ashutosh, Kotagiri, Shiva Prasad, Narayan, Ram, Hairong Gao, Ping Jing, Hom, Gary, Anshi Liang, Zhang, Eric, Kadkol, Aniket, Kothari, Ruchi, Chan, Gordon, Yehui Sun, Ge, Benjamin, Zeng, Jason, Ling, Kathy, Wang, Michael C., Malipatil, Amaresh, Lijun Li, Abel, Christopher, Zhong, Freeman

“…This paper presents a 28 Gb/s multistandard SerDes macro which is fabricated in TSMC 28 nm CMOS process. The transimpedance amplifier (TIA) base analog…”
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3-Pyridyloxypropanolamine agonists of the β3 adrenergic receptor with improved pharmacokinetic properties by Weber, Ann E, Ok, Hyun O, Alvaro, Raul F, Candelore, Mari R, Cascieri, Margaret A, Chiu, Shuet-Hing L, Deng, Liping, Forrest, Michael J, Hom, Gary J, Hutchins, Jennifer E, Kao, John, MacIntyre, D.Euan, Mathvink, Robert J, McLoughlin, Debra, Miller, Randall R, Newbold, Ronald C, Olah, Timothy V, Parmee, Emma R, Perkins, Leroy, Stearns, Ralph A, Strader, Catherine D, Szumiloski, John, Tang, Yui S, Tota, Laurie, Vicario, Pasquale P, Wyvratt, Matthew J, Fisher, Michael H

“…Pyridyloxypropanolamines L-749,372 ( 8, β 3 EC 50 = 3.6 nM) and L-750,355 ( 29, β 3 EC 50 = 13 nM) are selective partial agonists of the human receptor, with…”
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A 1.0625 ~ 14.025 Gb/s Multi-Media Transceiver With Full-Rate Source-Series-Terminated Transmit Driver and Floating-Tap Decision-Feedback Equalizer in 40 nm CMOS by ZHONG, Freeman, SHAOLEI QUAN, HUYNH, Tony, KIMURA, Hiroshi, KOTHARI, Ruchi, LIJUN LI, LIU, Cathy, LOWRIE, Scott, LING, Kathy, MALIPATIL, Amaresh, NARAYAN, Ram, PROKOP, Tom, WING LIU, PALUSA, Chai, RAJASHEKARA, Anil, SINHA, Ashutosh, ZHONG, Charlie, ZHANG, Eric, AZIZ, Pervez, TAI JING, JEN DONG, DESAI, Chintan, HAIRONG GAO, GARCIA, Monica, HOM, Gary

“…A 14.025 Gb/s multi-media transceiver employs on-die Rx AC coupling with baseline wander correction and equalizes up to 26 dB insertion loss at 14.025 Gb/s…”
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Human β 3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides by Brockunier, Linda L, Parmee, Emma R, Ok, Hyun O, Candelore, Mari R, Cascieri, Margaret A, Colwell, Lawrence F, Deng, Liping, Feeney, William P, Forrest, Michael J, Hom, Gary J, MacIntyre, D.Euan, Tota, Laurie, Wyvratt, Matthew J, Fisher, Michael H, Weber, Ann E

“…Compounds containing a 1,2,3-triazole-substituted benzenesulfonamide were prepared and found to be potent and selective human β 3-adrenergic receptor agonists…”
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A 1.0625 \sim 14.025 Gb/s Multi-Media Transceiver With Full-Rate Source-Series-Terminated Transmit Driver and Floating-Tap Decision-Feedback Equalizer in 40 nm CMOS by Zhong, F., Shaolei Quan, Wing Liu, Aziz, P., Tai Jing, Jen Dong, Desai, C., Hairong Gao, Garcia, M., Hom, G., Huynh, T., Kimura, H., Kothari, R., Lijun Li, Liu, C., Lowrie, S., Ling, K., Malipatil, A., Narayan, R., Prokop, T., Palusa, C., Rajashekara, A., Sinha, A., Zhong, C., Zhang, E.

“…A 14.025 Gb/s multi-media transceiver employs on-die Rx AC coupling with baseline wander correction and equalizes up to 26 dB insertion loss at 14.025 Gb/s…”
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A 1.0625-to-14.025Gb/s multimedia transceiver with full-rate source-series-terminated transmit driver and floating-tap decision-feedback equalizer in 40nm CMOS by Shaolei Quan, Zhong, F, Wing Liu, Aziz, P, Tai Jing, Jen Dong, Desai, C, Hairong Gao, Garcia, M, Hom, G, Huynh, Tony, Kimura, H, Kothari, R, Lijun Li, Liu, C, Lowrie, S, Ling, K, Malipatil, A, Narayan, R, Prokop, T, Palusa, C, Rajashekara, A, Sinha, A, Zhong, C, Zhang, E

“…A robust transceiver designed for NRZ signaling beyond 10Gb/s over long-range physical media (including electrical backplanes, copper cables and optical…”
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Comparison of Cardiovascular Parameters and/or Serum Chemistry and Hematology Profiles in Conscious and Anesthetized Rhesus Monkeys (Macaca mulatta) by Hom, Gary J., Bach, Thomas J., Carroll, Dayna, Forrest, Michael J., Mariano, Michele A., Trainor, Charlotte E., Wang, Pei-Ran, MacIntyre, D. Euan

“…The rhesus monkey is often used in pre-clinical research, and such studies frequently involve a variety of anesthetic conditions. Therefore, it is important to…”
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2.1 28Gb/s 560mW multi-standard SerDes with single-stage analog front-end and 14-tap decision-feedback equalizer in 28nm CMOS by Kimura, Hiroshi, Aziz, Pervez, Tai Jing, Sinha, Ashutosh, Narayan, Ram, Hairong Gao, Ping Jing, Hom, Gary, Liang, Anshi, Zhang, Eric, Kadkol, Aniket, Kothari, Ruchi, Chan, Gordon, Yehui Sun, Ge, Benjamin, Zeng, Jason, Ling, Kathy, Wang, Michael, Malipatil, Amaresh, Kotagiri, Shiva, Lijun Li, Abel, Chris, Zhong, Freeman

“…A high-speed SerDes must meet multiple challenges including high-speed operation, intensive equalization technique, low power consumption, small area and…”
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L-770,644: A potent and selective human β3 adrenergic receptor agonist with improved oral bioavailability by Shih, Thomas L., Candelore, Mari R., Cascieri, Margaret A., Chiu, Shuet-Hing L., Colwell, Lawrence F., Deng, Liping, Feeney, William P., Forrest, Michael J., Hom, Gary J., MacIntyre, D.Euan, Miller, Randall R., Stearns, Ralph A., Strader, Catherine D., Tota, Laurie, Wyvratt, Matthew J., Fisher, Michael H., Weber, Ann E.

“…L-770,644 ( 9c) is a potent and selective agonist of the human β 3 adrenergic receptor (EC 50 = 13 nM). It shows good oral bioavailability in both dogs and…”
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Activation of melanocortin MC(4) receptors increases erectile activity in rats ex copula by Martin, William J, McGowan, Erin, Cashen, Doreen E, Gantert, Liza T, Drisko, Jennifer E, Hom, Gary J, Nargund, Ravi, Sebhat, Iyassu, Howard, Andrew D, Van der Ploeg, Lex H T, MacIntyre, D Euan

“…Melanocortin peptide agonists, alpha-melanocyte stimulating hormone (alpha-MSH) and melanotan-II, stimulate erectile activity in a variety of species,…”
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Human β3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides by NAYLOR, E. M, PARMEE, E. R, FORREST, M. J, HOM, G. J, MACINTYRE, D. E, STRADER, C. D, TOTA, L, WANG, P.-R, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, COLANDREA, V. J, PERKINS, L, BROCKUNIER, L, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F, LIPING DENG, FEENEY, W. P

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L-750355, a human ß3-adrenoceptor agonist; in vitro pharmacology and profile of activity in vivo in the rhesus monkey by Forrest, Michael J, Hom, Gary, Bach, Tom, Candelore, Mari Rios, Cascieri, Margaret A, Strader, Catherine, Tota, Laurie, Fisher, Michael H, Szumiloski, John, Ok, Hyun O, Weber, Ann E, Wyvratt, Matthew, Vicario, Pasquale, Marko, Olga, Deng, Liping, Cioffe, Christine, Hegarty-Friscino, Bonnie, MacIntyre, Euan

“…The profile of in vitro and in vivo biology of a human ß3-adrenoceptor agonist, ( S)-…”
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Activation of melanocortin MC 4 receptors increases erectile activity in rats ex copula by Martin, William J, McGowan, Erin, Cashen, Doreen E, Gantert, Liza T, Drisko, Jennifer E, Hom, Gary J, Nargund, Ravi, Sebhat, Iyassu, Howard, Andrew D, Van der Ploeg, Lex H.T, MacIntyre, D.Euan

“…Melanocortin peptide agonists, α-melanocyte stimulating hormone (α-MSH) and melanotan-II, stimulate erectile activity in a variety of species, including man…”
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