Search Results - "HOLTACKERS, René"

Large‐scale image‐based profiling of single‐cell phenotypes in arrayed CRISPR‐Cas9 gene perturbation screens by de Groot, Reinoud, Lüthi, Joel, Lindsay, Helen, Holtackers, René, Pelkmans, Lucas

“…High‐content imaging using automated microscopy and computer vision allows multivariate profiling of single‐cell phenotypes. Here, we present methods for the…”
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Cytochrome P450 Alkane Hydroxylases of the CYP153 Family Are Common in Alkane-Degrading Eubacteria Lacking Integral Membrane Alkane Hydroxylases by VAN BEILEN, Jan B, FUNHOFF, Enrico G, VAN LOON, Alexander, JUST, Andrea, KAYSSER, Leo, BOUZA, Manuel, HOLTACKERS, René, RÖTHLISBERGER, Martina, ZHI LI, WITHOLT, Bernard

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Molecular control of kinetochore-microtubule dynamics and chromosome oscillations by Alonso, Maria, Wang, Enxiu, Lampson, Michael, Kingston, Isabel J, McAinsh, Andrew D, Meraldi, Patrick, Amaro, Ana C, Holtackers, René, Samora, Catarina P

“…The core kinetochore protein CENP-H is shown to be required for the organization of the metaphase plate. CENP-H regulates microtubule plus-end dynamics, and…”
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Kinetochores accelerate centrosome separation to ensure faithful chromosome segregation by McHedlishvili, Nunu, Wieser, Samuel, Holtackers, René, Mouysset, Julien, Belwal, Mukta, Amaro, Ana C, Meraldi, Patrick

“…At the onset of mitosis, cells need to break down their nuclear envelope, form a bipolar spindle and attach the chromosomes to microtubules via kinetochores…”
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Biocatalytic Production of Perillyl Alcohol from Limonene by Using a Novel Mycobacterium sp. Cytochrome P450 Alkane Hydroxylase Expressed in Pseudomonas putida by van Beilen, Jan B, Holtackers, René, Lůscher, Daniel, Bauer, Ulrich, Witholt, Bernard, Duetz, Wouter A

“…A number of oxygenated monoterpenes present at low concentrations in plant oils have anticarcinogenic properties. One of the most promising compounds in this…”
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Effect of Cell Shape and Dimensionality on Spindle Orientation and Mitotic Timing by Charnley, Mirren, Anderegg, Fabian, Holtackers, René, Textor, Marcus, Meraldi, Patrick

“…The formation and orientation of the mitotic spindle is a critical feature of mitosis. The morphology of the cell and the spatial distribution and composition…”
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The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A by Kress, Elsa, Schwager, Françoise, Holtackers, René, Seiler, Jonas, Prodon, François, Zanin, Esther, Eiteneuer, Annika, Toya, Mika, Sugimoto, Asako, Meyer, Hemmo, Meraldi, Patrick, Gotta, Monica

“…Coordination of cell cycle events in space and time is crucial to achieve a successful cell division. Here, we demonstrate that UBXN-2, a substrate adaptor of…”
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Post-transcriptional control of executioner caspases by RNA-binding proteins by Subasic, Deni, Stoeger, Thomas, Eisenring, Seline, Matia-González, Ana M, Imig, Jochen, Zheng, Xue, Xiong, Lei, Gisler, Pascal, Eberhard, Ralf, Holtackers, René, Gerber, André P, Pelkmans, Lucas, Hengartner, Michael O

“…Caspases are key components of apoptotic pathways. Regulation of caspases occurs at several levels, including transcription, proteolytic processing, inhibition…”
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Cell atlas of the regenerating human liver after portal vein embolization by Brazovskaja, Agnieska, Gomes, Tomás, Holtackers, Rene, Wahle, Philipp, Körner, Christiane, He, Zhisong, Schaffer, Theresa, Eckel, Julian Connor, Hänsel, René, Santel, Malgorzata, Seimiya, Makiko, Denecke, Timm, Dannemann, Michael, Brosch, Mario, Hampe, Jochen, Seehofer, Daniel, Damm, Georg, Camp, J. Gray, Treutlein, Barbara

“…The liver has the remarkable capacity to regenerate. In the clinic, regeneration is induced by portal vein embolization, which redirects portal blood flow,…”
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Multiscale chromatin dynamics and high entropy in plant iPSC ancestors by Rutowicz, Kinga, Lüthi, Joel, de Groot, Reinoud, Holtackers, René, Yakimovich, Yauhen, Pazmiño, Diana M, Gandrillon, Olivier, Pelkmans, Lucas, Baroux, Célia

“…Plant protoplasts provide starting material for of inducing pluripotent cell masses that are competent for tissue regeneration in vitro, analogous to animal…”
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Establishing standardized immune phenotyping of metastatic melanoma by digital pathology by Sobottka, Bettina, Nowak, Marta, Frei, Anja Laura, Haberecker, Martina, Merki, Samuel, Levesque, Mitchell P., Dummer, Reinhard, Moch, Holger, Ak, Melike, Albinus, Jonas, Alborelli, Ilaria, Andani, Sonali, Attinger, Per-Olof, Bacac, Marina, Baumhoer, Daniel, Beck-Schimmer, Beatrice, Beerenwinkel, Niko, Beisel, Christian, Bernasconi, Lara, Bodenmiller, Bernd, Bonilla, Ximena, Casanova, Ruben, Chevrier, Stéphane, Chicherova, Natalia, D'Costa, Maya, Danenberg, Esther, Davidson, Natalie, Drăganmoch, Monica-Andreea, Engler, Stefanie, Erkens, Martin, Eschbach, Katja, Esposito, Cinzia, Ferreira, Pedro, Ficek, Joanna, Grob, Linda, Gut, Gabriele, Günther, Detlef, Haberecker, Martina, Haeuptle, Pirmin, Holtackers, Rene, Huesser, Tamara, Irmisch, Anja, Jacob, Francis, Jacobs, Andrea, Jaeger, Tim M., Kahles, André, Kahraman, Abdullah, Kuebler, Werner, Kuipers, Jack, Kunze, Christian P., Kurzeder, Christian, Lehmann, Kjong-Van, Lugert, Sebastian, Maass, Gerd, Manz, Markus G., Markolin, Philipp, Mena, Julien, Menzel, Ulrike, Metzler, Julian M., Miglino, Nicola, Muenst, Simone, Murri, Riccardo, Ng, Charlotte K.Y., Nicolet, Stefan, Pedrioli, Patrick G.A., Pelkmans, Lucas, Piscuoglio, Salvatore, Ritter, Mathilde, Rosano-González, María L., Rätsch, Gunnar, Santacroce, Natascha, del Castillo, Jacobo Sarabia, Schlenker, Ramona, Schwalie, Petra C., Schwan, Severin, Senti, Gabriela, Snijder, Berend, Sreedharan, Vipin T., Stark, Stefan, Stekhoven, Daniel J., Theocharides, Alexandre P.A., Thomas, Tinu M., Tosevski, Vinko, Toussaint, Nora C., Tuncel, Mustafa A., Tusup, Marina, Van Drogen, Audrey, Vetter, Marcus, Weber, Sandra, Wegmann, Rebekka, Weller, Michael, Wendt, Fabian, Wey, Norbert, Wicki, Andreas, Wildschut, Mattheus HE, Wollscheid, Bernd, Yu, Shuqing, Ziegler, Johanna, Zimmermann, Marc, Zuend, Gregor

“…CD8+ tumor-infiltrating T cells can be regarded as one of the most relevant predictive biomarkers in immune-oncology. Highly infiltrated tumors, referred to as…”
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scROSHI: robust supervised hierarchical identification of single cells by Prummer, Michael, Bertolini, Anne, Bosshard, Lars, Barkmann, Florian, Yates, Josephine, Boeva, Valentina, Stekhoven, Daniel, Singer, Franziska

“…Abstract Identifying cell types based on expression profiles is a pillar of single cell analysis. Existing machine-learning methods identify predictive…”
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