Search Results - "HOLMGREN, Jan"

An Update on Cholera Immunity and Current and Future Cholera Vaccines by Holmgren, Jan

“…Individual resistance to cholera infection and disease depends on both innate host factors and adaptive immunity acquired by a previous infection or…”
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Migration routes and strategies in a highly aerial migrant, the common swift Apus apus, revealed by light-level geolocators by Åkesson, Susanne, Klaassen, Raymond, Holmgren, Jan, Fox, James W, Hedenström, Anders

“…The tracking of small avian migrants has only recently become possible by the use of small light-level geolocators, allowing the reconstruction of whole…”
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Evidence for several waves of global transmission in the seventh cholera pandemic by Mutreja, Ankur, Kim, Dong Wook, Thomson, Nicholas R., Connor, Thomas R., Lee, Je Hee, Kariuki, Samuel, Croucher, Nicholas J., Choi, Seon Young, Harris, Simon R., Lebens, Michael, Niyogi, Swapan Kumar, Kim, Eun Jin, Ramamurthy, T., Chun, Jongsik, Wood, James L. N., Clemens, John D., Czerkinsky, Cecil, Nair, G. Balakrish, Holmgren, Jan, Parkhill, Julian, Dougan, Gordon

“…Source of current cholera epidemic Cholera has affected human populations for centuries, and the agent responsible, Vibrio cholerae , continues to infect…”
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Requirement for Cyclic AMP/Protein Kinase A-Dependent Canonical NFκB Signaling in the Adjuvant Action of Cholera Toxin and Its Non-toxic Derivative mmCT by Terrinoni, Manuela, Holmgren, Jan, Lebens, Michael, Larena, Maximilian

“…Cholera toxin (CT) is widely used as an effective adjuvant in experimental immunology for inducing mucosal immune responses; yet its mechanisms of adjuvant…”
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5 year efficacy of a bivalent killed whole-cell oral cholera vaccine in Kolkata, India: a cluster-randomised, double-blind, placebo-controlled trial by Bhattacharya, Sujit K, MD, Sur, Dipika, MD, Ali, Mohammad, Dr, Kanungo, Suman, DIH, You, Young Ae, MS, Manna, Byomkesh, PhD, Sah, Binod, MBBS, Niyogi, Swapan K, MD, Park, Jin Kyung, PhD, Sarkar, Banwarilal, PhD, Puri, Mahesh K, MSc, Kim, Deok Ryun, MS, Deen, Jacqueline L, MD, Holmgren, Jan, PhD, Carbis, Rodney, BSc, Dhingra, Mandeep Singh, MD, Donner, Allan, PhD, Nair, G Balakrish, PhD, Lopez, Anna Lena, MD, Wierzba, Thomas F, PhD, Clemens, John D, MD

“…Summary Background Efficacy and safety of a two-dose regimen of bivalent killed whole-cell oral cholera vaccine (Shantha Biotechnics, Hyderabad, India) to 3…”
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A Double Mutant Heat-Labile Toxin from Escherichia coli, LT(R192G/L211A), Is an Effective Mucosal Adjuvant for Vaccination against Helicobacter pylori Infection by Sjökvist Ottsjö, Louise, Flach, Carl-Fredrik, Clements, John, Holmgren, Jan, Raghavan, Sukanya

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial by Sur, Dipika, MD, Lopez, Anna Lena, Dr, Kanungo, Suman, MBBS, Paisley, Allison, BS, Manna, Byomkesh, PhD, Ali, Mohammad, PhD, Niyogi, Swapan K, MD, Park, Jin Kyung, PhD, Sarkar, Banawarilal, PhD, Puri, Mahesh K, MS, Kim, Deok Ryun, MS, Deen, Jacqueline L, MD, Holmgren, Jan, Prof, Carbis, Rodney, BS, Rao, Raman, MD, Van, Nguyen Thu, PhD, Donner, Allan, Prof, Ganguly, Nirmal K, Prof, Nair, G Balakrish, PhD, Bhattacharya, Sujit K, MD, Clemens, John D, MD

“…Summary Background Oral cholera vaccines consisting of killed whole cells have been available for many years, but they have not been used extensively in…”
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Sublingual immunization induces broad-based systemic and mucosal immune responses in mice by Çuburu, Nicolas, Kweon, Mi-Na, Song, Joo-Hye, Hervouet, Catherine, Luci, Carmelo, Sun, Jia-Bin, Hofman, Paul, Holmgren, Jan, Anjuère, Fabienne, Czerkinsky, Cecil

“…Abstract The potential of sublingual (s.l.) delivery of vaccine was examined in mice. We show the existence of a dense network of dendritic cells (DCs) in the…”
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Surface expression of Helicobacter pylori HpaA adhesion antigen on Vibrio cholerae, enhanced by co-expressed enterotoxigenic Escherichia coli fimbrial antigens by Tobias, Joshua, Lebens, Michael, Wai, Sun Nyunt, Holmgren, Jan, Svennerholm, Ann-Mari

“…Helicobacter pylori infection can cause peptic ulceration and is associated with gastric adenocarcinoma. This study aimed to construct and characterize a…”
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Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice by Aradottir Pind, Audur Anna, Dubik, Magdalena, Thorsdottir, Sigrun, Meinke, Andreas, Harandi, Ali M, Holmgren, Jan, Del Giudice, Giuseppe, Jonsdottir, Ingileif, Bjarnarson, Stefania P

“…Immaturity of the immune system contributes to poor vaccine responses in early life. Germinal center (GC) activation is limited due to poorly developed…”
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Effect of protein release rates from tablet formulations on the immune response after sublingual immunization by Borde, Annika, Ekman, Annelie, Holmgren, Jan, Larsson, Anette

“…In vitro release rates of ovalbumin from sublingual tablet formulations with fast and extended release correlated with the effect on the elicited in vivo…”
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Cholera Due to Altered El Tor Strains of Vibrio cholerae O1 in Bangladesh by Nair, G. Balakrish, Qadri, Firdausi, Holmgren, Jan, Svennerholm, Ann-Mari, Safa, Ashrafus, Bhuiyan, Nurul A, Ahmad, Q. Shafi, Faruque, Shah M, Faruque, A.S.G, Takeda, Yoshifumi, Sack, David A

“…We determined the types of cholera toxin (CT) produced by a collection of 185 Vibrio cholerae O1 strains isolated in Bangladesh over the past 45 years. All of…”
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Development of stable Vibrio cholerae O1 Hikojima type vaccine strains co-expressing the Inaba and Ogawa lipopolysaccharide antigens by Karlsson, Stefan L, Ax, Elisabeth, Nygren, Erik, Källgård, Susanne, Blomquist, Margareta, Ekman, Annelie, Benktander, John, Holmgren, Jan, Lebens, Michael

“…We describe here the development of stable classical and El Tor V. cholerae O1 strains of the Hikojima serotype that co-express the Inaba and Ogawa antigens of…”
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Retrospective Analysis of Serotype Switching of Vibrio cholerae O1 in a Cholera Endemic Region Shows It Is a Non-random Process by Karlsson, Stefan L, Thomson, Nicholas, Mutreja, Ankur, Connor, Thomas, Sur, Dipika, Ali, Mohammad, Clemens, John, Dougan, Gordon, Holmgren, Jan, Lebens, Michael

“…Genomic data generated from clinical Vibrio cholerae O1 isolates collected over a five year period in an area of Kolkata, India with seasonal cholera outbreaks…”
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Efficacy of a low-cost, inactivated whole-cell oral cholera vaccine: results from 3 years of follow-up of a randomized, controlled trial by Sur, Dipika, Kanungo, Suman, Sah, Binod, Manna, Byomkesh, Ali, Mohammad, Paisley, Allison M, Niyogi, Swapan K, Park, Jin Kyung, Sarkar, Banawarilal, Puri, Mahesh K, Kim, Deok Ryun, Deen, Jacqueline L, Holmgren, Jan, Carbis, Rodney, Rao, Raman, Nguyen, Thu Van, Han, Seung Hyun, Attridge, Stephen, Donner, Allan, Ganguly, Nirmal K, Bhattacharya, Sujit K, Nair, G Balakrish, Clemens, John D, Lopez, Anna Lena

“…Killed oral cholera vaccines (OCVs) have been licensed for use in developing countries, but protection conferred by licensed OCVs beyond two years of follow-up…”
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Sublingual Immunization Protects against Helicobacter pylori Infection and Induces T and B Cell Responses in the Stomach by Raghavan, Sukanya, Östberg, Anna Karin, Flach, Carl-Fredrik, Ekman, Annelie, Blomquist, Margareta, Czerkinsky, Cecil, Holmgren, Jan

“…Sublingual (SL) immunization has been described as an effective novel way to induce mucosal immune responses in the respiratory and genital tracts. We examined…”
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Modern History of Cholera Vaccines and the Pivotal Role of icddr,b by Holmgren, Jan

“…Abstract The rapid spread of the seventh cholera pandemic over Asia in the 1960s led to several large field studies that revealed that the traditional…”
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A Protective Role of Locally Administered Immunostimulatory CpG Oligodeoxynucleotide in a Mouse Model of Genital Herpes Infection by Harandi, Ali M, Eriksson, Kristina, Holmgren, Jan

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A randomized, placebo-controlled trial of the bivalent killed, whole-cell, oral cholera vaccine in adults and children in a cholera endemic area in Kolkata, India by Mahalanabis, Dilip, Lopez, Anna Lena, Sur, Dipika, Deen, Jacqueline, Manna, Byomkesh, Kanungo, Suman, von Seidlein, Lorenz, Carbis, Rodney, Han, Seung Hyun, Shin, Seong Hye, Attridge, Stephen, Rao, Raman, Holmgren, Jan, Clemens, John, Bhattacharya, Sujit K

“…An effective vaccine against cholera has been used for public health purposes in Vietnam since the 1990s. This vaccine was reformulated to meet WHO…”
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Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin by Sun, Jia-Bin, Holmgren, Jan, Larena, Maximilian, Terrinoni, Manuela, Fang, Yu, Bresnick, Anne R, Xiang, Zou

“…The calcium-binding protein S100A4 has been described to promote pathological inflammation in experimental autoimmune and inflammatory disorders and in allergy…”
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