Search Results - "HOLCOMBE, SUSAN J"

Oxidative stress-induced mitochondrial dysfunction in a normal colon epithelial cell line by Packiriswamy, Nandakumar, Coulson, Kari F, Holcombe, Susan J, Sordillo, Lorraine M

“…AIM To determine how a normal human colon cell line reacts to microbial challenge as a way to study oxidative stress-induced responses associated with…”
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Plasma Lactate as a Predictor of Colonic Viability and Survival After 360° Volvulus of the Ascending Colon in Horses by JOHNSTON, KIMBERLY, HOLCOMBE, SUSAN J, HAUPTMAN, JOE G

“…To determine the relationship between plasma lactate concentration and colonic viability and survival in horses with >=360° volvulus of the ascending colon…”
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Multicenter Placebo-Controlled Randomized Study of Ethyl Pyruvate in Horses Following Surgical Treatment for ≥ 360° Large Colon Volvulus by Johnson, Lindsey M, Holcombe, Susan J, Shearer, Tara R, Watson, Victoria, Gandy, Jeffery, Southwood, Louise L, Lynch, Tymothy M, Schroeder, Eric L, Fogle, Callie A, Sordillo, Lorraine M

“…Identifying therapies that mitigate ischemic colonic injury and improve mucosal healing and intestinal viability are crucial to improving survival in horses…”
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Prevalence of Laryngeal Disease in a Large Population of Competition Draft Horses by Brakenhoff, J. E, Holcombe, S. J, Hauptman, J. G, Smith, H. K, Nickels, F. A, Caron, J. P

“…(1) To determine the effect of age, height, weight, breed, sex, and specific use on the prevalence of idiopathic left laryngeal hemiplegia (ILH) in a…”
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Serum Vitamin D Level Is Unchanged in Equine Asthma by Mainguy-Seers, Sophie, Holcombe, Susan J., Lavoie, Jean-Pierre

“…Vitamin D deficiency is associated with asthma development and severity of symptoms in humans, but whether the same occurs in horses is unknown. We aimed to…”
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Incisional infections associated with ventral midline celiotomy in horses by Shearer, Tara R., Holcombe, Susan J., Valberg, Stephanie J.

“…Objective To review the veterinary literature regarding healing and complications associated with equine celiotomy including anatomy and physiology, risk…”
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Cricothyroid Muscle Function and Vocal Fold Stability in Exercising Horses by HOLCOMBE, SUSAN J, RODRIGUEZ, KATIE, LANE, JENNIFER, CARON, JOHN P

“…To determine (1) if the cricothyroid muscle had respiratory-related electromyographic (EMG) activity that increased with respiratory effort and (2) if…”
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Preliminary heritability of complete rotation large colon volvulus in Thoroughbred broodmares by Petersen, Jessica L, Lewis, Ronald M, Embertson, Rolf, Valberg, Stephanie J, Holcombe, Susan J

“…Large colon volvulus (LCV) is a life-threatening form of colic that occurs when the large colon rotates 360° or more on its axis, resulting in colonic…”
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The Effect of Core Abdominal Muscle Rehabilitation Exercises on Return to Training and Performance in Horses After Colic Surgery by Holcombe, Susan J., Shearer, Tara R., Valberg, Stephanie J.

“…We conducted a retrospective cohort study to test the hypothesis that performing 4 weeks of core abdominal rehabilitation exercises (CARE) postoperatively…”
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Effects of intravenous ethyl pyruvate on cardiopulmonary variables and quality of recovery from anesthesia in horses by Muñoz, Kirk A, Szarek, Meagan, Manfredi, Jane M, Robertson, Sheilah A, Hubbell, John Ae, Holcombe, Susan J

“…To determine the effects of intravenous ethyl pyruvate, an anti-inflammatory with putative benefits in horses with endotoxemia, on cardiopulmonary variables…”
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Plasma lactate as a predictor of colonic viability and survival after 360 degrees volvulus of the ascending colon in horses by Johnston, Kimberly, Holcombe, Susan J, Hauptman, Joe G

“…To determine the relationship between plasma lactate concentration and colonic viability and survival in horses with >or=360 degrees volvulus of the ascending…”
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Duration of in vivo endotoxin tolerance in horses by Holcombe, Susan J., Jacobs, Carrie C., Cook, Vanessa L., Gandy, Jeffery C., Hauptman, Joseph G., Sordillo, Lorraine M.

“…Endotoxemia models are used to study mechanisms and treatments of early sepsis. Repeated endotoxin exposures induce periods of endotoxin tolerance,…”
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Effects of hyaluronate‐carboxymethylcellulose membranes on the clinical outcome of horses undergoing emergency exploratory celiotomy by Troy, Jarrod R., Holcombe, Susan J., Fogle, Callie A., Epstein, Kira L., Woodie, J. Brett

“…Objective To determine the influence of hyaluronate‐carboxymethylcellulose (HA‐CMC) membranes applied to intestinal anastomoses or enterotomies on…”
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End-to-Side Versus Side-to-Side Jejunocecostomy in Horses: A Retrospective Analysis of 150 Cases by Brown, Jennifer A., Holcombe, Susan J., Southwood, Louise L., Byron, Christopher R., Embertson, Rolf M., Hauptmann, Joe G.

“…Objectives To determine factors associated with postoperative reflux, postoperative colic, repeat celiotomy, and survival in horses after end‐to‐side (E2S) or…”
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Ethyl pyruvate decreases proinflammatory gene expression in lipopolysaccharide-stimulated equine monocytes by Cook, Vanessa L., Holcombe, Susan J., Gandy, Jeffrey C., Corl, Christine M., Sordillo, Lorraine M.

“…Monocytes are among the initial cells that interact with circulating LPS. Binding of LPS to monocyte surface receptors triggers an intracellular signaling…”
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Prevalence of and Risk Factors for Postoperative Ileus after Small Intestinal Surgery in Two Hundred and Thirty-Three Horses by HOLCOMBE, SUSAN J, RODRIGUEZ, KATIE M, HAUPT, JENNIFER L, CAMPBELL, JAMES O, CHANEY, KRISTIN P, SPARKS, HOLLY D, HAUPTMAN, JOE G

“…To determine the incidence of postoperative ileus (POI) in a population of horses after small intestinal surgery and the effect of multiple variables on…”
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Spurious hypercreatininemia: 28 neonatal foals (2000-2008) by Chaney, Kristin P, Holcombe, Susan J, Schott, Harold C. II, Barr, Bonnie S

“…To (1) determine the occurrence of spurious hypercreatininemia in a population of hospitalized foals <2 days old, (2) assess the resolution of the…”
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Resection and Anastomosis of the Descending Colon in 43 Horses by Prange, Timo, Holcombe, Susan J, Brown, Jennifer A, Dechant, Julie E, Fubini, Susan L, Embertson, Rolf M, Peroni, John, Rakestraw, Peter C, Hauptman, Joe G

“…To determine (1) the short- (to hospital discharge) and long- (>6 months) term survival, (2) factors associated with short-term survival, and (3) the…”
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Nutrition of critically ill horses by Carr, Elizabeth A, Holcombe, Susan J

“…Nutritional supplementation is becoming the standard of practice in equine medicine, although there are minimal data on nutritional support in critically ill…”
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OBJECTIVE RADIOGRAPHIC ASSESSMENT OF ABDOMINAL SAND ACCUMULATION IN HORSES by KEPPIE, NATHAN J, ROSENSTEIN, DIANA S, HOLCOMBE, SUSAN J, SCHOTT, HAROLD C. II

“…Gastrointestinal sand accumulation is a common cause of equine colic. Subjective assessment of sand accumulation on abdominal radiographs has been used as a…”
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