Search Results - "HOKFELT, T"

On the origin of eating disorders: altered signaling between gut microbiota, adaptive immunity and the brain melanocortin system regulating feeding behavior by Fetissov, Sergueï O, Hökfelt, Tomas

“…Research in the field of gut microbiota – brain axis may contribute to clarifying the origin of anorexia nervosa and bulimia, the two principal forms of eating…”
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Galanin, galanin receptor subtypes and depression-like behaviour by Kuteeva, E, Hökfelt, T, Wardi, T, Ogren, S O

“…The pathophysiology of depression remains unclear, but involves disturbances in brain monoaminergic transmission. Current antidepressant drugs, which act by…”
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Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness by Hökfelt, Tomas, Barde, Swapnali, Xu, Zhi-Qing David, Kuteeva, Eugenia, Rüegg, Joelle, Le Maitre, Erwan, Risling, Mårten, Kehr, Jan, Ihnatko, Robert, Theodorsson, Elvar, Palkovits, Miklos, Deakin, William, Bagdy, Gyorgy, Juhasz, Gabriella, Prud'homme, H Josée, Mechawar, Naguib, Diaz-Heijtz, Rochellys, Ögren, Sven Ove

“…Neuropeptides are auxiliary messenger molecules that always co-exist in nerve cells with one or more small molecule (classic) neurotransmitters. Neuropeptides…”
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Galanin receptor 2 overexpressing mice display an antidepressive-like phenotype: possible involvement of the subiculum by Wardi Le Maître, T, Xia, S, Le Maitre, E, Dun, X.-P, Lu, J, Theodorsson, E, Ögren, S.O, Hökfelt, T, Xu, Z.-Q.D

“…Abstract The behavioral phenotype of a transgenic mouse overexpressing a galanin receptor 2 (GalR2)-enhanced, green fluorescent protein (EGFP)-construct under…”
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G-protein-coupled receptors: an update by Fredholm, B.B, Hökfelt, T, Milligan, G

“…The receptors that couple to G proteins (GPCR) and which span the cell membranes seven times (7-TM receptors) were the focus of a symposium in Stockholm 2006…”
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Differential influence of nerve growth factor on neuropeptide expression in vivo: a novel role in peptide suppression in adult sensory neurons by Verge, VM, Richardson, PM, Wiesenfeld-Hallin, Z, Hokfelt, T

“…In this study the actions of NGF in regulating peptide expression were examined in vivo in adult rat primary sensory neurons. The hypothesis that NGF might…”
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The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond by Keimpema, Erik, Hökfelt, Tomas, Harkany, Tibor, Doherty, Patrick

“…Neurotrophins are traditionally known for their roles in neuronal development, function and survival. More recent data has highlighted the importance of…”
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Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation by Ji, RR, Zhang, Q, Law, PY, Low, HH, Elde, R, Hokfelt, T

“…Recently, antisera that recognize unique epitopes of the cloned mu-, delta-, and kappa-opioid, receptors (MOR, DOR, KOR, respectively) have been developed. In…”
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High nitric oxide production in human paranasal sinuses by Lundberg, J.O.N, Farkas-Szallasi, T, Weitzberg, E, Rinder, J, Lidholm, J, Änggåard, A, Hökfelt, T, Lundberg, J.M, Alving, K

“…Nitric oxide (NO) is present in air derived from the nasal airways. However, the precise origin and physiological role of airway-derived NO are unknown. We…”
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The new neuroendocrinology—a perspective by Hokfelt, T

“…Content List ‐ Read more articles from the symposium: Neuroendocrine Interfaces in Physiology and Disease…”
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The galanin receptor 2/3 agonist Gal2-11 protects the SN56 cells against β-amyloid25-35 toxicity by Pirondi, S., Giuliani, A., Del Vecchio, G., Giardino, L., Hökfelt, T., Calzà, L.

“…The neuropeptide galanin is a modulator of cholinergic function and may play a role in Aβ peptide‐induced degeneration of cholinergic forebrain neurons. We…”
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Expression of the vesicular glutamate transporters-1 and -2 in adult mouse dorsal root ganglia and spinal cord and their regulation by nerve injury by Brumovsky, P, Watanabe, M, Hökfelt, T

“…Abstract The expression of two vesicular glutamate transporters (VGLUTs), VGLUT1 and VGLUT2 , was studied with immunohistochemistry in lumbar dorsal root…”
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Systematically generated antibodies against human gene products: High throughput screening on sections from the rat nervous system by Mulder, J, Wernérus, H, Shi, T.-J, Pontén, F, Hober, S, Uhlén, M, Hökfelt, T

“…Abstract Completion of the Human Genome Project and recent developments in proteomics make it possible to systematically generate affinity reagents to a large…”
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Expression of neuropeptide Y and neuropeptide Y (Y1) receptor mRNA in rat spinal cord and dorsal root ganglia following peripheral tissue inflammation by Ji, RR, Zhang, X, Wiesenfeld-Hallin, Z, Hokfelt, T

“…By using in situ hybridization histochemistry and immunohistochemistry, neuropeptide Y (NPY) and NPY (Y1) receptor mRNA as well as NPY-like immunoreactivity…”
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Bone marrow stromal cells attenuate injury-induced changes in galanin, NPY and NPY Y 1-receptor expression after a sciatic nerve constriction by Coronel, M.F., Musolino, P.L., Brumovsky, P.R., Hökfelt, T., Villar, M.J.

“…Single ligature nerve constriction (SLNC) of the rat sciatic nerve triggers neuropathic pain-related behaviors and induces changes in neuropeptide expression…”
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Tissue Profiling of the Mammalian Central Nervous System Using Human Antibody-based Proteomics by Mulder, Jan, Björling, Erik, Jonasson, Kalle, Wernérus, Henrik, Hober, Sophia, Hökfelt, Tomas, Uhlén, Mathias

“…A need exists for mapping the protein profiles in the human brain both during normal and disease conditions. Here we studied 800 antibodies generated toward…”
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Deletion of the neuropeptide YY1 receptor affects pain sensitivity, neuropeptide transport and expression, and dorsal root ganglion neuron numbers by Shi, TJS, Li, J, Dahlström, A, Theodorsson, E, Ceccatelli, S, Decosterd, I, Pedrazzini, T, Hökfelt, T

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Characterization of neuropeptide Y Y2 and Y5 receptor expression in the mouse hypothalamus by Fetissov, Sergueï O., Byrne, Leah C., Hassani, Hessameh, Ernfors, Patrik, Hökfelt, Tomas

“…Neuropeptide Y (NPY) neurons abundantly innervate the hypothalamus, where NPY is involved in the regulation of a broad range of homeostatic functions. In the…”
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Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF by Verge, VM, Merlio, JP, Grondin, J, Ernfors, P, Persson, H, Riopelle, RJ, Hokfelt, T, Richardson, PM

“…The distributions of mRNAs for the protooncogene trk and the low-affinity NGF receptor (LNGFR) were studied by hybridization with oligonucleotide probes on…”
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Galanin and spinal nociceptive mechanisms: recent advances and therapeutic implications by Xu, X.J, Hökfelt, T, Bartfai, T, Wiesenfeld-Hallin, Z

“…Galanin is a peptide consisting of 29 or 30 (in humans) amino acids that is present in sensory and spinal dorsal horn neurons. Endogenous galanin may have an…”
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