Search Results - "HOHL, DANIEL"
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The human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the 'fused genes' family
Published in Experimental dermatology (01-09-2012)“…: The skin is essential for survival and protects our body against biological attacks, physical stress, chemical injury, water loss, ultraviolet radiation and…”
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Skin Colonization by Staphylococcus aureus Precedes the Clinical Diagnosis of Atopic Dermatitis in Infancy
Published in Journal of investigative dermatology (01-12-2017)“…Atopic dermatitis (AD) has a well-established association with skin colonization or infection by Staphylococcus aureus, which can exacerbate the disease…”
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3
HOPX Exhibits Oncogenic Activity during Squamous Skin Carcinogenesis
Published in Journal of investigative dermatology (01-10-2021)“…Cutaneous squamous cell carcinomas (SCCs) are frequent heterogeneous tumors arising from sun-exposed regions of the skin and characterized by complex…”
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4
Birt–Hogg–Dubé syndrome
Published in European respiratory review (30-09-2020)“…Birt–Hogg–Dubé syndrome (BHD) is a rare inherited autosomal dominant disorder caused by germline mutations in the tumour suppressor gene FLCN , encoding the…”
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NRF3 suppresses squamous carcinogenesis, involving the unfolded protein response regulator HSPA5
Published in EMBO molecular medicine (08-11-2023)“…Epithelial skin cancers are extremely common, but the mechanisms underlying their malignant progression are still poorly defined. Here, we identify the NRF3…”
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A Child with a Lump in the Neck: A Quiz
Published in Acta dermato-venereologica (08-01-2024)“…Abstract is missing (Quiz)…”
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The Fate of Epidermal Tight Junctions in the stratum corneum: Their Involvement in the Regulation of Desquamation and Phenotypic Expression of Certain Skin Conditions
Published in International journal of molecular sciences (01-07-2022)“…We evaluated the presence of tight junction (TJ) remnants in the stratum corneum (SC) of in vitro reconstructed human epidermis and human skin explants…”
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Challenges in Treating Genodermatoses: New Therapies at the Horizon
Published in Frontiers in pharmacology (05-01-2022)“…Genodermatoses are rare inherited skin diseases that frequently affect other organs. They often have marked effects on wellbeing and may cause early death…”
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PASS Syndrome: An IL-1-Driven Autoinflammatory Disease
Published in Dermatology (Basel) (01-01-2016)“…PASS syndrome is a rare inflammatory disease characterized by a chronic-relapsing course of pyoderma gangrenosum, acne vulgaris, hidradenitis suppurativa and…”
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Birth of a Melanoma
Published in Dermatology practical & conceptual (01-05-2022)Get full text
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Diaper dermatitis prevalence and severity: Global perspective on the impact of caregiver behavior
Published in Pediatric dermatology (01-01-2020)“…Objectives To compare prevalence and severity of diaper dermatitis (DD) in infants and toddlers (babies) across three countries (China, USA, and Germany),…”
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IL-17 receptor A and adenosine deaminase 2 deficiency in siblings with recurrent infections and chronic inflammation
Published in Journal of allergy and clinical immunology (01-04-2016)“…Background Data on patients affected by chronic mucocutaneous candidiasis underscore the preponderant role of IL-17 receptor A (IL-17RA) in preserving…”
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Dual Role of the Antioxidant Enzyme Peroxiredoxin 6 in Skin Carcinogenesis
Published in Cancer research (Chicago, Ill.) (01-06-2013)“…The antioxidant enzyme peroxiredoxin 6 (Prdx6) is a key regulator of the cellular redox balance, particularly under stress conditions. We identified Prdx6 as…”
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Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin
Published in PloS one (18-02-2010)“…The Notch pathway is essential for proper epidermal differentiation during embryonic skin development. Moreover, skin specific loss of Notch signaling in the…”
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Nrf2 Activation Promotes Keratinocyte Survival during Early Skin Carcinogenesis via Metabolic Alterations
Published in Cancer research (Chicago, Ill.) (15-11-2015)“…Pharmacologic activation of the transcription factor NRF2 has been suggested to offer a strategy for cancer prevention. In this study, we present evidence from…”
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Cytokine-pathway blockers worsen mycosis fungoides masquerading as psoriasis
Published in JAAD Case Reports (01-06-2024)Get full text
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Case Report: Pansclerotic Morphea-Clinical Features, Differential Diagnoses and Modern Treatment Concepts
Published in Frontiers in immunology (09-03-2021)“…Pansclerotic morphea (PSM) is a rare skin disease characterized by progressive stiffening of the skin with or without the typical superficial skin changes…”
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Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis
Published in PloS one (23-08-2016)“…Harlequin Ichthyosis is a severe skin disease caused by mutations in the human gene encoding ABCA12. Here, we characterize a novel mutation in intron 29 of the…”
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Activin promotes skin carcinogenesis by attraction and reprogramming of macrophages
Published in EMBO molecular medicine (01-01-2017)“…Activin has emerged as an important player in different types of cancer, but the underlying mechanisms are largely unknown. We show here that activin…”
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UVB-Induced Skin Inflammation and Cutaneous Tissue Injury Is Dependent on the MHC Class I–Like Protein, CD1d
Published in Journal of investigative dermatology (01-01-2014)“…CD1d is a major histocompatibility complex class 1–like molecule that regulates the function and development of natural killer T (NKT) cells. Previously, we…”
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