Search Results - "HOGAN, Simon"

Intestinal barrier function: Molecular regulation and disease pathogenesis by Groschwitz, Katherine R., BS, Hogan, Simon P., PhD

“…The intestinal epithelium is a single-cell layer that constitutes the largest and most important barrier against the external environment. It acts as a…”
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Severity grading system for acute allergic reactions—time for validation and assessment of best practices by Hogan, Simon P.

“…Given that there are already a number of acute allergic reaction classification systems described and others being formulated, it would seem timely that the…”
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Self-Assembled Monolayers of Oligophenylenecarboxylic Acids on Silver Formed at the Liquid–Solid Interface by Aitchison, Hannah, Lu, Hao, Hogan, Simon W. L, Früchtl, Herbert, Cebula, Izabela, Zharnikov, Michael, Buck, Manfred

“…A series of para-oligophenylene mono- and dicarboxylic acids (R-(C6H4) n COOH, n = 1–3, R = H,COOH) was studied. Adsorbed on Au(111)/mica modified by an…”
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The eosinophil by Rothenberg, Marc E, Hogan, Simon P

“…Eosinophils have been considered end-stage cells involved in host protection against parasites. However, numerous lines of evidence have now changed this…”
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Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy by Chen, Chun-Yu, Lee, Jee-Boong, Liu, Bo, Ohta, Shoichiro, Wang, Pin-Yi, Kartashov, Andrey V., Mugge, Luke, Abonia, J. Pablo, Barski, Artem, Izuhara, Kenji, Rothenberg, Marc E., Finkelman, Fred D., Hogan, Simon P., Wang, Yui-Hsi

“…Experimental IgE-mediated food allergy depends on intestinal anaphylaxis driven by interleukin-9 (IL-9). However, the primary cellular source of IL-9 and the…”
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Intestinal epithelial cells in tolerance and allergy to dietary antigens by Newberry, Rodney D., Hogan, Simon P.

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Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling by Giles, Daniel A, Moreno-Fernandez, Maria E, Stankiewicz, Traci E, Graspeuntner, Simon, Cappelletti, Monica, Wu, David, Mukherjee, Rajib, Chan, Calvin C, Lawson, Matthew J, Klarquist, Jared, Sünderhauf, Annika, Softic, Samir, Kahn, C Ronald, Stemmer, Kerstin, Iwakura, Yoichiro, Aronow, Bruce J, Karns, Rebekah, Steinbrecher, Kris A, Karp, Christopher L, Sheridan, Rachel, Shanmukhappa, Shiva K, Reynaud, Damien, Haslam, David B, Sina, Christian, Rupp, Jan, Hogan, Simon P, Divanovic, Senad

“…Current mouse models of nonalcoholic steatohepatitis are limited, making identification and preclinical testing of new treatments challenging. Housing mice at…”
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Competition between hydrogen and halogen bonding in halogenated 1-methyluracil: Water systems by Hogan, Simon W.L., van Mourik, Tanja

“…The competition between hydrogen‐ and halogen‐bonding interactions in complexes of 5‐halogenated 1‐methyluracil (XmU; X = F, Cl, Br, I, or At) with one or two…”
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New Class of Metal Bound Molecular Switches Involving H‑Tautomerism by Simpson, Grant J, Hogan, Simon W. L, Caffio, Marco, Adams, Christopher J, Früchtl, Herbert, van Mourik, Tanja, Schaub, Renald

“…A potential end-point in the miniaturization of electronic devices lies in the field of molecular electronics, where molecules perform the function of single…”
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Eosinophilic esophagitis: Immune mechanisms and therapeutic targets by Khokhar, Dilawar, Marella, Sahiti, Idelman, Gila, Chang, Joy W., Chehade, Mirna, Hogan, Simon P.

“…Eosinophilic esophagitis (EoE) is an emerging chronic inflammatory disease of the oesophagus and is clinically characterized by upper gastrointestinal (GI)…”
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IL-25 and CD4+ TH2 cells enhance type 2 innate lymphoid cell–derived IL-13 production, which promotes IgE-mediated experimental food allergy by Lee, Jee-Boong, Chen, Chun-Yu, Liu, Bo, Mugge, Luke, Angkasekwinai, Pornpimon, Facchinetti, Valeria, Dong, Chen, Liu, Yong-Jun, Rothenberg, Marc E., Hogan, Simon P., Finkelman, Fred D., Wang, Yui-Hsi

“…Food-mediated allergic reactions have emerged as a major health problem. The underlying mechanisms that promote uncontrolled type 2 immune responses to dietary…”
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Modeling TH2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma by Foster, Paul S., Maltby, Steven, Rosenberg, Helene F., Tay, Hock L., Hogan, Simon P., Collison, Adam M., Yang, Ming, Kaiko, Gerard E., Hansbro, Philip M., Kumar, Rakesh K., Mattes, Joerg

“…Summary In this review, we highlight experiments conducted in our laboratories that have elucidated functional roles for CD4+ T‐helper type‐2 lymphocytes (TH2…”
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Halogen bonding in mono‐ and dihydrated halobenzene by Hogan, Simon W. L., van Mourik, Tanja

“…Density functional theory calculations were performed on halogen‐bonded and hydrogen‐bonded systems consisting of a halobenzene (XPh; X = F, Cl, Br, I, and At)…”
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Mucosal IgA immune complex induces immunomodulatory responses in allergic airway and intestinal TH2 disease by Elesela, Srikanth, Arzola-Martínez, Llilian, Rasky, Andrew, Ptaschinski, Catherine, Hogan, Simon P., Lukacs, Nicholas W.

“…BACKGROUNDIgA is the most abundant immunoglobulin at the mucosal surface and although its role in regulating mucosal immunity is not fully understood, its…”
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Investigating innate immune mechanisms in early-life development and outcomes of food allergy by Dang, Andrew, Logsdon, Stephanie, Hogan, Simon P.

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It’s getting hot in here: The interface between obesity, influenza, and thermoneutrality by O'Dwyer, David N., Hogan, Simon P.

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Eosinophils: Biological Properties and Role in Health and Disease by HOGAN, SIMON P., ROSENBERG, HELENE F., MOQBEL, REDWAN, PHIPPS, SIMON, FOSTER, PAUL S., LACY, PAIGE, KAY, A. BARRY, ROTHENBERG, MARC E.

“…SUMMARY Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation of diverse inflammatory responses, as well as modulators…”
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Importance of Cytokines in Murine Allergic Airway Disease and Human Asthma by Finkelman, Fred D, Hogan, Simon P, Hershey, Gurjit K. Khurana, Rothenberg, Marc E, Wills-Karp, Marsha

“…Asthma is a common, disabling inflammatory respiratory disease that has increased in frequency and severity in developed nations. We review studies of murine…”
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Goblet cell associated antigen passages support the induction and maintenance of oral tolerance by Kulkarni, Devesha H., Gustafsson, Jenny K., Knoop, Kathryn A., McDonald, Keely G., Bidani, Shay S., Davis, Jazmyne E., Floyd, Alexandria N., Hogan, Simon P., Hsieh, Chyi-Song, Newberry, Rodney D.

“…Tolerance to innocuous antigens from the diet and the commensal microbiota is a fundamental process essential to health. Why tolerance is efficiently induced…”
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IL-4 receptor alpha signaling alters oral food challenge and immunotherapy outcomes in mice by Ganesan, Varsha, Sharma, Ankit, Tomar, Sunil, Schuler, Charles F., Hogan, Simon P.

“…Food allergy diagnosis and management causes a number of social and emotional challenges for individuals with food allergies and their caregivers. This has led…”
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