Search Results - "HOFFMANN, Maria"
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AMRFinderPlus and the Reference Gene Catalog facilitate examination of the genomic links among antimicrobial resistance, stress response, and virulence
Published in Scientific reports (16-06-2021)“…Antimicrobial resistance (AMR) is a significant public health threat. With the rise of affordable whole genome sequencing, in silico approaches to assessing…”
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Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs)
Published in Annals of the rheumatic diseases (01-02-2021)“…Interstitial lung diseases (ILDs), which can arise from a broad spectrum of distinct aetiologies, can manifest as a pulmonary complication of an underlying…”
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Performance of Candidate Serum Biomarkers for Systemic Sclerosis–Associated Interstitial Lung Disease
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-06-2019)“…Objective Interstitial lung disease (ILD) in systemic sclerosis (SSc) runs a highly variable course, and prediction tools are highly desired. The aim of this…”
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From Big Data Technologies to Big Data Benefits
Published in Computer (Long Beach, Calif.) (01-06-2023)“…In this article, we present an approach used in Vestas Wind Systems A/S for managing the realization of potential benefits from big data technologies. This…”
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Nintedanib in Patients With Autoimmune Disease–Related Progressive Fibrosing Interstitial Lung Diseases: Subgroup Analysis of the INBUILD Trial
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-06-2022)“…Objective To analyze the efficacy and safety of nintedanib in patients with fibrosing autoimmune disease–related interstitial lung diseases (ILDs) with a…”
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Tracking Impact of Interstitial Lung Disease in Systemic Sclerosis in a Complete Nationwide Cohort
Published in American journal of respiratory and critical care medicine (15-11-2019)“…Interstitial lung disease (ILD) represents a major challenge in systemic sclerosis (SSc), but there are no precise, population-based data on its overall…”
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Nanopore sequencing for fast determination of plasmids, phages, virulence markers, and antimicrobial resistance genes in Shiga toxin-producing Escherichia coli
Published in PloS one (30-07-2019)“…Whole genome sequencing can provide essential public health information. However, it is now known that widely used short-read methods have the potential to…”
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Mycophenolate Mofetil Versus Placebo for Systemic Sclerosis–Related Interstitial Lung Disease: An Analysis of Scleroderma Lung Studies I and II
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2017)“…Objective To compare mycophenolate mofetil (MMF) with placebo for the treatment of systemic sclerosis (SSc)–related interstitial lung disease (ILD). Methods We…”
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Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis
Published in The European respiratory journal (01-05-2022)“…Radiomic features calculated from routine medical images show great potential for personalised medicine in cancer. Patients with systemic sclerosis (SSc), a…”
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Benchmarking short and long read polishing tools for nanopore assemblies: achieving near-perfect genomes for outbreak isolates
Published in BMC genomics (08-07-2024)“…Oxford Nanopore provides high throughput sequencing platforms able to reconstruct complete bacterial genomes with 99.95% accuracy. However, even small levels…”
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Presence of disinfectant resistance genes in Escherichia coli isolated from retail meats in the USA
Published in Journal of antimicrobial chemotherapy (01-10-2014)“…To examine the distribution of all genes known to be responsible for resistance to quaternary ammonium compounds (QACs), and their association with resistance…”
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CCL21 as a Potential Serum Biomarker for Pulmonary Arterial Hypertension in Systemic Sclerosis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-10-2018)“…Objective Systemic sclerosis (SSc) is a major cause of pulmonary arterial hypertension (PAH). Murine models indicate key roles for chemokines CCL19 and CCL21…”
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Anticentromere Antibody Levels and Isotypes and the Development of Systemic Sclerosis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-12-2021)“…Objective Little is known on the disease course of very early systemic sclerosis (SSc). Among the information yet to be elucidated is whether anticentromere…”
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Interstitial lung disease in systemic sclerosis: progress in screening and early diagnosis
Published in Current opinion in rheumatology (01-11-2016)“…PURPOSE OF REVIEWInterstitial lung disease (ILD) is the major determinant of morbidity and mortality in systemic sclerosis (SSc). In highly selected SSc…”
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Estimation of the Prevalence of Progressive Fibrosing Interstitial Lung Diseases: Systematic Literature Review and Data from a Physician Survey
Published in Advances in therapy (01-02-2021)“…Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic…”
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Genes significantly associated with lineage II food isolates of Listeria monocytogenes
Published in BMC genomics (25-09-2018)“…Listeria monocytogenes is a widespread foodborne pathogen that can cause listeriosis, a potentially fatal infection. L. monocytogenes is subdivided into four…”
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Association of Lymphangiogenic Factors With Pulmonary Arterial Hypertension in Systemic Sclerosis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2021)“…Objective Pulmonary arterial hypertension (PAH) is a major complication in systemic sclerosis (SSc), a disease marked by vascular and lymphatic vessel…”
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The need for a holistic approach for SSc-ILD - achievements and ambiguity in a devastating disease
Published in Respiratory research (23-07-2020)“…Systemic sclerosis (SSc) is a multi-organ autoimmune disease with complex interactions between immune-mediated inflammatory processes and vascular pathology…”
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Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
Published in Rheumatology (Oxford, England) (01-10-2020)“…Abstract Objective SSc is a severe, heterogeneous multi-organ disease where population-based estimates on phenotypic spectrum, overall disease burden and…”
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Genomic features of colistin resistant Escherichia coli ST69 strain harboring mcr-1 on IncHI2 plasmid from raw milk cheese in Egypt
Published in Infection, genetics and evolution (01-09-2019)“…There is emerging evidence that food of animal origin may be responsible for the spread of multidrug resistant extraintestinal pathogenic Escherichia coli in…”
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