Search Results - "HOFFMANN, Ingrid"

Role of Polo-like Kinases Plk1 and Plk4 in the Initiation of Centriole Duplication-Impact on Cancer by Hoffmann, Ingrid

“…Centrosomes nucleate and anchor microtubules and therefore play major roles in spindle formation and chromosome segregation during mitosis. Duplication of the…”
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Food consumption of adults in Germany: results of the German National Nutrition Survey II based on diet history interviews by Heuer, Thorsten, Krems, Carolin, Moon, Kilson, Brombach, Christine, Hoffmann, Ingrid

“…The second German National Nutrition Survey (NVS II) aimed to evaluate food consumption and other aspects of nutritional behaviour of a representative sample…”
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Trends in food consumption and nutrient intake in Germany between 2006 and 2012: results of the German National Nutrition Monitoring (NEMONIT) by Gose, Maria, Krems, Carolin, Heuer, Thorsten, Hoffmann, Ingrid

“…The German National Nutrition Monitoring (NEMONIT) is a longitudinal and nationwide study to assess changes in food consumption and nutrient intake in Germany…”
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Activated Ezrin controls MISP levels to ensure correct NuMA polarization and spindle orientation by Kschonsak, Yvonne T, Hoffmann, Ingrid

“…Correct spindle orientation is achieved through signaling pathways that provide a molecular link between the cell cortex and spindle microtubules in an F-actin…”
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Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization by Pesenti, Marion E., Raisch, Tobias, Conti, Duccio, Walstein, Kai, Hoffmann, Ingrid, Vogt, Dorothee, Prumbaum, Daniel, Vetter, Ingrid R., Raunser, Stefan, Musacchio, Andrea

“…Centromeres are specialized chromosome loci that seed the kinetochore, a large protein complex that effects chromosome segregation. A 16-subunit complex, the…”
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Metabolite patterns predicting sex and age in participants of the Karlsruhe Metabolomics and Nutrition (KarMeN) study by Rist, Manuela J, Roth, Alexander, Frommherz, Lara, Weinert, Christoph H, Krüger, Ralf, Merz, Benedikt, Bunzel, Diana, Mack, Carina, Egert, Björn, Bub, Achim, Görling, Benjamin, Tzvetkova, Pavleta, Luy, Burkhard, Hoffmann, Ingrid, Kulling, Sabine E, Watzl, Bernhard

“…Physiological and functional parameters, such as body composition, or physical fitness are known to differ between men and women and to change with age. The…”
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Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome by Cizmecioglu, Onur, Arnold, Marc, Bahtz, Ramona, Settele, Florian, Ehret, Lena, Haselmann-Weiss, Uta, Antony, Claude, Hoffmann, Ingrid

“…Both gain and loss of function studies have identified the Polo-like kinase Plk4/Sak as a crucial regulator of centriole biogenesis, but the mechanisms…”
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MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression by Vodicska, Barbara, Cerikan, Berati, Schiebel, Elmar, Hoffmann, Ingrid

“…Precise mitotic spindle orientation is essential for both cell fate and tissue organization while defects in this process are associated with tumorigenesis and…”
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Cdc25 Phosphatases Are Required for Timely Assembly of CDK1-Cyclin B at the G2/M Transition by Timofeev, Oleg, Cizmecioglu, Onur, Settele, Florian, Kempf, Tore, Hoffmann, Ingrid

“…Progression through mitosis requires the coordinated regulation of Cdk1 kinase activity. Activation of Cdk1 is a multistep process comprising binding of Cdk1…”
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Epstein–Barr virus particles induce centrosome amplification and chromosomal instability by Shumilov, Anatoliy, Tsai, Ming-Han, Schlosser, Yvonne T., Kratz, Anne-Sophie, Bernhardt, Katharina, Fink, Susanne, Mizani, Tuba, Lin, Xiaochen, Jauch, Anna, Mautner, Josef, Kopp-Schneider, Annette, Feederle, Regina, Hoffmann, Ingrid, Delecluse, Henri-Jacques

“…Infections with Epstein–Barr virus (EBV) are associated with cancer development, and EBV lytic replication (the process that generates virus progeny) is a…”
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Types of Nutrition Knowledge, Their Socio-Demographic Determinants and Their Association With Food Consumption: Results of the NEMONIT Study by Koch, Franziska, Hoffmann, Ingrid, Claupein, Erika

“…To investigate nutrition knowledge in the German population, its determinants and its association with food consumption. Data were obtained from the NEMONIT…”
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Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling by Primorac, Ivana, Weir, John R, Chiroli, Elena, Gross, Fridolin, Hoffmann, Ingrid, van Gerwen, Suzan, Ciliberto, Andrea, Musacchio, Andrea

“…Regulation of macromolecular interactions by phosphorylation is crucial in signaling networks. In the spindle assembly checkpoint (SAC), which enables…”
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Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy by Martin, Carol-Anne, Ahmad, Ilyas, Klingseisen, Anna, Hussain, Muhammad Sajid, Bicknell, Louise S, Leitch, Andrea, Nürnberg, Gudrun, Toliat, Mohammad Reza, Murray, Jennie E, Hunt, David, Khan, Fawad, Ali, Zafar, Tinschert, Sigrid, Ding, James, Keith, Charlotte, Harley, Margaret E, Heyn, Patricia, Müller, Rolf, Hoffmann, Ingrid, Daire, Valérie Cormier, Dollfus, Hélène, Dupuis, Lucie, Bashamboo, Anu, McElreavey, Kenneth, Kariminejad, Ariana, Mendoza-Londono, Roberto, Moore, Anthony T, Saggar, Anand, Schlechter, Catie, Weleber, Richard, Thiele, Holger, Altmüller, Janine, Höhne, Wolfgang, Hurles, Matthew E, Noegel, Angelika Anna, Baig, Shahid Mahmood, Nürnberg, Peter, Jackson, Andrew P

“…Andrew Jackson, Peter Nürnberg and colleagues identify mutations in PLK4 and TUBGCP6 in individuals with microcephaly, primordial dwarfism, retinopathy and…”
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PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle by Chang, Jaerak, Cizmecioglu, Onur, Hoffmann, Ingrid, Rhee, Kunsoo

“…Control of centrosome duplication is tightly linked with the progression of the cell cycle. Recent studies suggest that the fundamental process of centriole…”
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Plk4-dependent phosphorylation of STIL is required for centriole duplication by Kratz, Anne-Sophie, Bärenz, Felix, Richter, Kai T, Hoffmann, Ingrid

“…Duplication of centrioles, namely the formation of a procentriole next to the parental centriole, is regulated by the polo-like kinase Plk4. Only a few other…”
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A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint by Overlack, Katharina, Primorac, Ivana, Vleugel, Mathijs, Krenn, Veronica, Maffini, Stefano, Hoffmann, Ingrid, Kops, Geert J P L, Musacchio, Andrea

“…The spindle assembly checkpoint (SAC) monitors and promotes kinetochore-microtubule attachment during mitosis. Bub1 and BubR1, SAC components, originated from…”
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Plk2 regulates centriole duplication through phosphorylation-mediated degradation of Fbxw7 (human Cdc4) by Cizmecioglu, Onur, Krause, Annekatrin, Bahtz, Ramona, Ehret, Lena, Malek, Nisar, Hoffmann, Ingrid

“…Polo-like kinases (Plks) perform crucial functions during mitosis, cytokinesis and centriole duplication. Plk2 is activated in early G1 phase and is involved…”
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The SCF-Fbxw5 E3-ubiquitin ligase is regulated by Plk4 and targets HsSAS-6 to control centrosome duplication by Malek, Nisar P, Puklowski, Anja, Homsi, Yahya, Keller, Debora, May, Martin, Chauhan, Sangeeta, Kossatz, Uta, Grünwald, Viktor, Kubicka, Stefan, Pich, Andreas, Manns, Michael P, Hoffmann, Ingrid, Gönczy, Pierre

“…Deregulated centrosome duplication can result in genetic instability and contribute to tumorigenesis. Here, we show that centrosome duplication is regulated by…”
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Ectopic Expression of Cdc25A Accelerates the G1/S Transition and Leads to Premature Activation of Cyclin E- and Cyclin A-Dependent Kinases by Blomberg, Ida, Hoffmann, Ingrid

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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GCP6 is a substrate of Plk4 and required for centriole duplication by Bahtz, Ramona, Seidler, Joerg, Arnold, Marc, Haselmann-Weiss, Uta, Antony, Claude, Lehmann, Wolf D, Hoffmann, Ingrid

“…Centriole duplication occurs once per cell cycle and requires Plk4, a member of the Polo-like kinase family. A key component of the centrosome is the γ-tubulin…”
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