Search Results - "HOERR, I"

Polarization of immunity induced by direct injection of naked sequence-stabilized mRNA vaccines by Carralot, J-P, Probst, J, Hoerr, I, Scheel, B, Teufel, R, Jung, G, Rammensee, H-G, Pascolo, S

“…In the context of developing a safe genetic vaccination strategy we tested and studied globin-stabilized mRNA-based vaccination in mice. This vaccination…”
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Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent by PROBST, J, WEIDE, B, SCHEEL, B, PICHLER, B. J, HOERR, I, RAMMENSEE, H.-G, PASCOLO, S

“…The development of new treatments in the post-genomic era requires methods for safe delivery of foreign genetic information in vivo. As a transient, natural…”
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Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent by Probst, J, Weide, B, Scheel, B, Pichler, B.J, Hoerr, I, Rammensee, H.-G, Pascolo, S

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Human peripheral blood mononuclear cells transfected with messenger RNA stimulate antigen-specific cytotoxic T-lymphocytes in vitro by Teufel, R, Carralot, J-P, Scheel, B, Probst, J, Walter, S, Jung, G, Hoerr, I, Rammensee, H-G, Pascolo, S

“…The efficiency of test vaccines needs to be evaluated by quantification of the triggered cellular immune response. Usually, for these assays, autologous target…”
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Human peripheral blood monuclear cells transfected with messenger RNA stimulate antigen-specific cytotoxic T-lymphocytes in vitro by Teufel, R., Carralot, J.-P., Scheel, B., Probst, J., Walter, S., Jung, G., Hoerr, I., Rammensee, H.-G., Pascolo, S.

“…The efficiency of test vaccines needs to be evaluated by quantification of the triggered cellular immune response. Usually, for these assays, autologous target…”
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Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients by WEIDE, Benjamin, PASCOLO, Steve, SCHEEL, Birgit, DERHOVANESSIAN, Evelyna, PFLUGFELDER, Annette, EIGENTLER, Thomas K, PAWELEC, Graham, HOERR, Ingmar, RAMMENSEE, Hans-Georg, GARBE, Claus

“…In mice, injection of messenger RNA (mRNA) coding for tumor-associated antigens can induce antitumor immune responses and therefore offers a broadly applicable…”
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Results of the First Phase I/II Clinical Vaccination Trial With Direct Injection of mRNA by WEIDE, Benjamin, CARRALOT, Jean-Philippe, REESE, Anne, SCHEEL, Birgit, EIGENTLER, Thomas Kurt, HOERR, Ingmar, RAMMENSEE, Hans-Georg, GARBE, Claus, PASCOLOF, Steve

“…Vaccination against tumor antigens has been shown to be a safe and efficacious prophylactic and therapeutic antitumor treatment in many animal models. Clinical…”
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In vivo application of RNA leads to induction of specific cytotoxic T lymphocytes and antibodies by Hoerr, Ingmar, Obst, Reinhard, Rammensee, Hans‐Georg, Jung, Günther

“…To study the efficiency of RNA‐based vaccines, RNA coding for the model antigen β‐galactosidase (β‐gal) was transcribed in vitro from a lacZ gene flanked by…”
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Erratum: Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent by Probst, J, Weide, B, Scheel, B, Pichler, B J, Hoerr, I, Rammensee, H-G, Pascolo, S

“…Correction to: Gene Therapy (2007) 14, 1175–1180; doi:10.1038/sj.gt.3302964 Since the above publication the authors have noticed that they unfortunately missed…”
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Characterization of a Novel, Antifungal Chitin-Binding Protein from Streptomyces tendae Tue901 That Interferes with Growth Polarity by Bormann, C, Baier, D, Hoerr, I, Raps, C, Berger, J, Jung, G, Schwarz, H

“…The afp1 gene, which encodes the antifungal protein AFP1, was cloned from nikkomycin-producing Streptomyces tendae Tue901, using a nikkomycin-negative mutant…”
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Evaluation of a theory-based community intervention to increase fruit and vegetable intakes of women with limited incomes by Chung, Sang-Jin, Hoerr, Sharon L

“…The study objectives were to increase both the stage of readiness to eat fruit and vegetables as well as the intakes of women who participated in the Expanded…”
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