Search Results - "HOEFGEN, Barbara"

The power of sample size and homogenous sampling: Association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorder by Hoefgen, Barbara, Schulze, Thomas G., Ohlraun, Stephanie, von Widdern, Olrik, Höfels, Susanne, Gross, Magdalena, Heidmann, Vivien, Kovalenko, Svetlana, Eckermann, Anita, Kölsch, Heike, Metten, Martin, Zobel, Astrid, Becker, Tim, Nöthen, Markus M., Propping, Peter, Heun, Reinhard, Maier, Wolfgang, Rietschel, Marcella

“…Several lines of evidence indicate that abnormalities in the functioning of the central serotonergic system are involved in the pathogenesis of affective…”
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A possible genetic link between MTHFR genotype and smoking behavior by Linnebank, Michael, Moskau, Susanna, Semmler, Alexander, Hoefgen, Barbara, Bopp, Gisela, Kallweit, Ulf, Maier, Wolfgang, Schütz, Christian G, Wüllner, Ullrich

“…Hyperhomocysteinemia is an independent risk factor for stroke and other vascular events. The variant methylenetetrahydrofolate reductase (MTHFR) C677T is…”
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Digital health applications (DiGA): assessment of reimbursability by means of the "DiGA Fast Track" procedure at the Federal Institute for Drugs and Medical Devices (BfArM) by Lauer, Wolfgang, Löbker, Wiebke, Höfgen, Barbara

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Further Evidence for Association of Variants in the AKT1 Gene with Schizophrenia in a Sample of European Sib-Pair Families by Schwab, Sibylle G., Hoefgen, Barbara, Hanses, Claudia, Hassenbach, Margitta Borrmann, Albus, Margot, Lerer, Bernard, Trixler, Matyas, Maier, Wolfgang, Wildenauer, Dieter B.

“…Involvement of AKT signaling pathways in schizophrenia has been recently suggested, on the basis of several lines of evidence. In addition to impairment of…”
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Dopamine/Serotonin Receptor Ligands. 10: SAR Studies on Azecine-type Dopamine Receptor Ligands by Functional Screening at Human Cloned D 1 , D 2L , and D 5 Receptors with a Microplate Reader Based Calcium Assay Lead to a Novel Potent D 1 /D 5 Selective Antagonist by Hoefgen, Barbara, Decker, Michael, Mohr, Patrick, Schramm, Astrid M., Rostom, Sherif A. F., El-Subbagh, Hussein, Schweikert, Peter M., Rudolf, Dirk R., Kassack, Matthias U., Lehmann, Jochen

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Dopamine/Serotonin Receptor Ligands. 10: SAR Studies on Azecine-type Dopamine Receptor Ligands by Functional Screening at Human Cloned D1, D2L, and D5 Receptors with a Microplate Reader Based Calcium Assay Lead to a Novel Potent D1/D5 Selective Antagonist by Hoefgen, Barbara, Decker, Michael, Mohr, Patrick, Schramm, Astrid M, Rostom, Sherif A. F, El-Subbagh, Hussein, Schweikert, Peter M, Rudolf, Dirk R, Kassack, Matthias U, Lehmann, Jochen

“…On the basis of the benz[d]indolo[2,3-g]azecine derivative 1 (LE300), structure−activity relations were investigated in order to identify the pharmacophore in…”
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Association of DNA Polymorphisms in the Synaptic Vesicular Amine Transporter Gene (SLC18A2) with Alcohol and Nicotine Dependence by SCHWAB, Sibylle G, FRANKE, Petra E, HOEFGEN, Barbara, GUTTENTHALER, Vera, LICHTERMANN, Dirk, TRIXLER, Matyas, KNAPP, Michael, MAIER, Wolfgang, WILDENAUER, Dieter B

“…The brain synaptic vesicular amine transporter SLCA18A2 is a key component for the uptake of monoamines like dopamine or serotonin into vesicles. We have…”
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Innovationsunterstützung im BfArM – Erfahrungen aus den Beratungen zu digitalen Gesundheitsanwendungen (DiGA) by Löbker, Wiebke, Böhmer, Anne Christin, Höfgen, Barbara

“…Zusammenfassung Seit Mai 2020 können Hersteller einen Antrag zur Aufnahme einer digitalen Gesundheitsanwendung (DiGA) in das Verzeichnis nach § 139e Fünftes…”
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Dopamine/serotonin receptor ligands. 10:1 SAR studies on azecine-type dopamine receptor ligands by functional screening at human cloned D1, D2L, and D5 receptors with a microplate reader based calcium assay lead to a novel potent D1/D5 selective antagonist by HOEFGEN, Barbara, DECKER, Michael, MOHR, Patrick, SCHRARNM, Astrid M, ROSTOM, Sherif A. F, EL-SUBBAGH, Hussein, SCHWEIKERT, Peter M, RUDOLF, Dirk R, KASSACK, Matthias U, LEHMANN, Jochen

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Dibenzazecine compounds with a novel dopamine/5HT2A receptor profile and 3D-QSAR analysis by Hamacher, Alexandra, Weigt, Mathias, Wiese, Michael, Hoefgen, Barbara, Lehmann, Jochen, Kassack, Matthias U

“…Antipsychotics are divided into typical and atypical compounds based on clinical efficacy and side effects. The purpose of this study was to characterize in…”
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Dibenzazecine compounds with a novel dopamine/5H[T.sub.2A] receptor profile and 3D-QSAR analysis by Hamacher, Alexandra, Weigt, Mathias, Wiese, Michael, Hoefgen, Barbara, Lehmann, Jochen, Kassack, Matthias U

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Dopamine/Serotonin Receptor Ligands, Part III [1]: Synthesis and Biological Activities of 7, 7′-Alkylene-bis-6, 7, 8, 9, 14, 15-hexahydro-5H-benz[d]indolo[2, 3-g]azecines - Application of the Bivalent Ligand Approach to a Novel Type of Dopamine Receptor Antagonist by Abadi, Ashraf H., Lankow, Stefan, Hoefgen, Barbara, Decker, Michael, Kassack, Matthias U., Lehmann, Jochen

“…A series of 7, 7′—alkylene‐bridged dimers(7a—e) of the benz [d]indolo[3, 2‐f]azecine derivative LE300 was synthesized. Affinity and functional activity at…”
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Digitale Gesundheitsanwendungen (DiGA): Bewertung der Erstattungsfähigkeit mittels DiGA-Fast-Track-Verfahrens im Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) by Lauer, Wolfgang, Löbker, Wiebke, Höfgen, Barbara

“…Zusammenfassung Mit dem Digitale-Versorgung-Gesetz (DVG) hat der Gesetzgeber digitalen Gesundheitsanwendungen, kurz DiGA, einen Einzug in die Regelversorgung…”
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Support for innovation at the BfArM-experiences from the consultations on digital health applications (DiGA) by Löbker, Wiebke, Böhmer, Anne Christin, Höfgen, Barbara

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