Search Results - "HOCK, Thomas"

Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance by Hecker, Louise, Logsdon, Naomi J, Kurundkar, Deepali, Kurundkar, Ashish, Bernard, Karen, Hock, Thomas, Meldrum, Eric, Sanders, Yan Y, Thannickal, Victor J

“…The incidence and prevalence of pathological fibrosis increase with advancing age, although mechanisms for this association are unclear. We assessed the…”
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A far-upstream AP-1/Smad binding box regulates human NOX4 promoter activation by transforming growth factor-β by Bai, Guangxing, Hock, Thomas D., Logsdon, Naomi, Zhou, Yong, Thannickal, Victor J.

“…NADPH oxidase 4 (NOX4) is a member of the NADPH oxidase gene family that regulates cellular differentiation, innate immunity and tissue fibrosis. Transforming…”
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Stromal cell-derived factor 1 promotes angiogenesis via a heme oxygenase 1-dependent mechanism by Deshane, Jessy, Chen, Sifeng, Caballero, Sergio, Grochot-Przeczek, Anna, Was, Halina, Li Calzi, Sergio, Lach, Radoslaw, Hock, Thomas D, Chen, Bo, Hill-Kapturczak, Nathalie, Siegal, Gene P, Dulak, Jozef, Jozkowicz, Alicja, Grant, Maria B, Agarwal, Anupam

“…Stromal cell-derived factor 1 (SDF-1) plays a major role in the migration, recruitment, and retention of endothelial progenitor cells to sites of ischemic…”
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Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions by Wright, Marcienne M, Kim, Junghyun, Hock, Thomas D, Leitinger, Norbert, Freeman, Bruce A, Agarwal, Anupam

“…Nitro-fatty acid products of oxidative inflammatory reactions mediate anti-inflammatory cell signalling responses. LNO2 (nitrolinoleic acid) induces expression…”
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Sp1 Regulates Chromatin Looping between an Intronic Enhancer and Distal Promoter of the Human Heme Oxygenase-1 Gene in Renal Cells by Deshane, Jessy, Kim, Junghyun, Bolisetty, Subhashini, Hock, Thomas D., Hill-Kapturczak, Nathalie, Agarwal, Anupam

“…HO-1 (heme oxygenase-1) is an inducible microsomal enzyme that catalyzes the degradation of pro-oxidant heme. The goal of this study was to characterize a…”
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Histone deacetylase inhibition downregulates collagen 3A1 in fibrotic lung fibroblasts by Zhang, Xiangyu, Liu, Hui, Hock, Thomas, Thannickal, Victor J, Sanders, Yan Y

“…Idiopathic pulmonary fibrosis (IPF) is a deadly disease characterized by chronic inflammation and excessive collagen accumulation in the lung. Myofibroblasts…”
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The story so far: Molecular regulation of the heme oxygenase-1 gene in renal injury by Sikorski, Eric M, Hock, Thomas, Hill-Kapturczak, Nathalie, Agarwal, Anupam

“…Heme oxygenases (HOs) catalyze the rate-limiting step in heme degradation, resulting in the formation of iron, carbon monoxide, and biliverdin, the latter of…”
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The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling by LIBY, Karen, HOCK, Thomas, GRIBBLE, Gordon W, HILL-KAPTURCZAK, Nathalie, AGARWAL, Anupam, SPORN, Michael B, YORE, Mark M, SUH, Nanjoo, PLACE, Andrew E, RISINGSONG, Renee, WILLIAMS, Charlotte R, ROYCE, Darlene B, HONDA, Tadashi, HONDA, Yukiko

“…The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO) and its derivative…”
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JunB and JunD Regulate Human Heme Oxygenase-1 Gene Expression in Renal Epithelial Cells by Hock, Thomas D., Liby, Karen, Wright, Marcienne M., McConnell, Sean, Schorpp-Kistner, Marina, Ryan, Thomas M., Agarwal, Anupam

“…Heme oxygenase-1 is a highly inducible gene, the product of which catalyzes breakdown of the prooxidant heme. The purpose of this study was to investigate the…”
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Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells by Kelley, Eric E., Hock, Thomas, Khoo, Nicholas K.H., Richardson, Gloria R., Johnson, Kamorris K., Powell, Pamela C., Giles, Gregory I., Agarwal, Anupam, Lancaster, Jack R., Tarpey, Margaret M.

“…Xanthine oxidoreductase (XOR) activity has been previously noted to be responsive to changes in O 2 tension. While prior studies have focused on the extremes…”
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Halothane binds to druggable sites in the [Ca2+]4-calmodulin (CaM) complex, but does not inhibit [Ca2+]4-CaM activation of kinase by Juranić Nenad O., Jones Keith A., Penheiter Alan R., Hock Thomas J., Streiff John H.

“…The mechanism(s) of volatile anesthetics (VA) are poorly understood. We used high resolution NMR spectroscopy to determine the structure of the…”
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Upstream stimulatory factors, USF1 and USF2, bind to the human haem oxygenase-1 proximal promoter in vivo and regulate its transcription by Hock, Thomas D, Nick, Harry S, Agarwal, Anupam

“…The human HO-1 (haem oxygenase-1) gene encodes a microsomal enzyme responsible for the breakdown of haem, and is also cytoprotective in response to various…”
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Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis by Karki, Suman, Surolia, Ranu, Hock, Thomas David, Guroji, Purusotham, Zolak, Jason S., Duggal, Ryan, Ye, Tong, Thannickal, Victor J., Antony, Veena B.

“…Pleural mesothelial cells (PMCs), which are derived from the mesoderm, exhibit an extraordinary capacity to undergo phenotypic changes during development and…”
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Pleural Mesothelial Cell Differentiation and Invasion in Fibrogenic Lung Injury by Zolak, Jason S, Jagirdar, Rajesh, Surolia, Ranu, Karki, Suman, Oliva, Octavio, Hock, Thomas, Guroji, Purushotham, Ding, Qiang, Liu, Riu-Ming, Bolisetty, Subhashini, Agarwal, Anupam, Thannickal, Victor J, Antony, Veena B

“…The origin of the myofibroblast in fibrotic lung disease is uncertain, and no effective medical therapy for fibrosis exists. We have previously demonstrated…”
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Specificity protein 1 and Smad-dependent regulation of human heme oxygenase-1 gene by transforming growth factor-beta1 in renal epithelial cells by Traylor, Amie, Hock, Thomas, Hill-Kapturczak, Nathalie

“…Excess transforming growth factor-beta1 (TGF-beta1) in the kidney leads to increased cell proliferation and deposition of extracellular matrix, resulting in…”
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On-line Nanoparticle Size Distribution Measurements of a 15kw Pellet Burner by F. Schneider, J. Spielvogel, T. Hock, M. Pesch

“…Abstract preview not available - see full-text PDF article…”
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Polymorphisms in the human xeroderma pigmentosum group A gene and their impact on cell survival and nucleotide excision repair by Mellon, Isabel, Hock, Thomas, Reid, Rollie, Porter, Paul C., States, J.Christopher

“…Polymorphisms in DNA repair genes may contribute to defects in DNA repair and increased susceptibility to cancer. The xeroderma pigmentosum group A ( XPA) gene…”
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Regulation of the human heme oxygenase-1 gene by Hock, Thomas D

“…The heme oxygenase-1 (HO-1) gene encodes a microsomal enzyme that catalyzes the conversion of heme to carbon monoxide, Iron, and biliverdin. HO-1 transcription…”
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Getting to Work: Training and Support for Transportation Needs by West, Michael, Hock, Thomas, Wittig, Kathe, Dowdy, Vicki

“…Case studies of transportation needs of individuals with severe disabilities illustrate various methods of training them in transportation use and locating…”
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Everybody's Doing It: A National Study of the Use of Natural Supports in Supported Employment by West, Michael D, Kregel, John, Hernandez, Ana, Hock, Thomas

“…Reports findings from a survey of 385 supported employment agencies on their use of natural supports in time-lined and extended services. Eighty-five percent…”
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