Search Results - "HOCH, James A"

Identification of direct residue contacts in protein-protein interaction by message passing by Weigt, Martin, White, Robert A, Szurmant, Hendrik, Hoch, James A, Hwa, Terence

“…Understanding the molecular determinants of specificity in protein-protein interaction is an outstanding challenge of postgenome biology. The availability of…”
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Structural basis of histidine kinase autophosphorylation deduced by integrating genomics, molecular dynamics, and mutagenesis by Dago, Angel E, Schug, Alexander, Procaccini, Andrea, Hoch, James A, Weigt, Martin, Szurmant, Hendrik

“…Signal transduction proteins such as bacterial sensor histidine kinases, designed to transition between multiple conformations, are often ruled by unstable…”
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Two-component and phosphorelay signal transduction by Hoch, James A

“…Two-component and phosphorelay signal transduction systems are the major means by which bacteria recognize and respond to a variety of environmental stimuli…”
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Interaction fidelity in two-component signaling by Szurmant, Hendrik, Hoch, James A

“…Two component signal transduction systems and phosphorelays have been adapted and amplified by bacteria to respond to a multitude of environmental, metabolic…”
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Essentiality, bypass, and targeting of the YycFG (VicRK) two-component regulatory system in gram-positive bacteria by Winkler, Malcolm E, Hoch, James A

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role for the essential YycG sensor histidine kinase in sensing cell division by Fukushima, Tatsuya, Furihata, Isako, Emmins, Robyn, Daniel, Richard A, Hoch, James A, Szurmant, Hendrik

“…The YycG sensor histidine kinase co-ordinates cell wall remodelling with cell division in Gram-positive bacteria by controlling the transcription of genes for…”
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essential sensor histidine kinase controlled by transmembrane helix interactions with its auxiliary proteins by Szurmant, Hendrik, Bu, Lintao, Brooks, Charles L. III, Hoch, James A

“…Two-component signal transduction systems with membrane-embedded sensor histidine kinases are believed to recognize environmental signals and transduce this…”
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YycH and YycI Interact To Regulate the Essential YycFG Two-Component System in Bacillus subtilis by SZURMANT, Hendrik, MOHAN, Michael A, IMUS, P. Michael, HOCH, James A

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Inference of direct residue contacts in two-component signaling by Lunt, Bryan, Szurmant, Hendrik, Procaccini, Andrea, Hoch, James A, Hwa, Terence, Weigt, Martin

“…Since the onset of the genomic era more than 1000 bacterial genomes have been sequenced and several fold more are expected to be completed in the near future…”
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Opposing effects of histidine phosphorylation regulate the AtxA virulence transcription factor in Bacillus anthracis by Tsvetanova, Billyana, Wilson, Adam C, Bongiorni, Cristina, Chiang, Christina, Hoch, James A, Perego, Marta

“…Expression of genes for Bacillus anthracis toxin and capsule virulence factors are dependent upon the AtxA transcription factor. The mechanism by which AtxA…”
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A Life in Bacillus subtilis Signal Transduction by Hoch, James A

“…This is a tale of how technology drove the discovery of the molecular basis for signal transduction in the initiation of sporulation in Bacillus subtilis and…”
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Two small c-type cytochromes affect virulence gene expression in Bacillus anthracis by Wilson, Adam C, Hoch, James A, Perego, Marta

“…Regulated expression of the genes for anthrax toxin proteins is essential for the virulence of the pathogenic bacterium Bacillus anthracis. Induction of toxin…”
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A Two-Component Signal Transduction System Essential for Growth of Bacillus subtilis: Implications for Anti-Infective Therapy by Fabret, C, Hoch, J A

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Features of protein-protein interactions in two-component signaling deduced from genomic libraries by White, Robert A, Szurmant, Hendrik, Hoch, James A, Hwa, Terence

“…As more and more sequence data become available, new approaches for extracting information from these data become feasible. This chapter reports on one such…”
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Keeping signals straight in phosphorelay signal transduction by Hoch, J A, Varughese, K I

“…Bacteria are highly adaptable organisms, and the key is their capacity to express only those genes for enzymes and pathways that they need for maximal growth…”
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YycH Regulates the Activity of the Essential YycFG Two-Component System in Bacillus subtilis by SZURMANT, Hendrik, NELSON, Kristine, KIM, Eun-Ja, PEREGO, Marta, HOCH, James A

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A Unique GTP-Dependent Sporulation Sensor Histidine Kinase in Bacillus anthracis by SCARAMOZZINO, Francesca, WHITE, Andrea, PEREGO, Marta, HOCH, James A

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Phosphorylation and functional analysis of the sporulation initiation factor Spo0A from Clostridium botulinum by Wörner, Kristina, Szurmant, Hendrik, Chiang, Christina, Hoch, James A.

“…Summary The initiation of sporulation in aerobic Bacillus species is regulated by the phosphorelay consisting of several sensor histidine kinases, the Spo0F…”
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Crystal structure of the transcriptional repressor PagR of Bacillus anthracis by Zhao, Haiyan, Volkov, Arsen, Veldore, Vidya Harini, Hoch, James A, Varughese, Kottayil I

“…1 Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA 2 Department of Physiology and Biophysics,…”
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Dual Promoters Control Expression of the Bacillus anthracis Virulence Factor AtxA by BONGIORNI, Cristina, FUKUSHIMA, Tatsuya, WILSON, Adam C, CHIANG, Christina, CECILIA MANSILLA, M, HOCH, James A, PEREGO, Marta

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