Search Results - "HO, Mark N"

Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome by DEMO, Susan D, KIRK, Christopher J, SHENK, Kevin D, SMYTH, Mark S, SUN, Congcong M, VALLONE, Marcy K, WOO, Tina M, MOLINEAUX, Christopher J, BENNETT, Mark K, AUJAY, Monette A, BUCHHOLZ, Tonia J, DAJEE, Maya, HO, Mark N, JING JIANG, LAIDIG, Guy J, LEWIS, Evan R, PARLATI, Francesco

“…Clinical studies with bortezomib have validated the proteasome as a therapeutic target for the treatment of multiple myeloma and non-Hodgkin's lymphoma…”
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Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047) by Zhou, Han-Jie, Aujay, Monette A, Bennett, Mark K, Dajee, Maya, Demo, Susan D, Fang, Ying, Ho, Mark N, Jiang, Jing, Kirk, Christopher J, Laidig, Guy J, Lewis, Evan R, Lu, Yan, Muchamuel, Tony, Parlati, Francesco, Ring, Eileen, Shenk, Kevin D, Shields, Jamie, Shwonek, Peter J, Stanton, Timothy, Sun, Congcong M, Sylvain, Catherine, Woo, Tina M, Yang, Jinfu

“…Proteasome inhibition has been validated as a therapeutic modality in the treatment of multiple myeloma and Non-Hodgkin’s lymphoma. Carfilzomib, an epoxyketone…”
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Glucuronidation of trans-resveratrol by human liver and intestinal microsomes and UGT isoforms by Brill, Shirley S., Furimsky, Anna M., Ho, Mark N., Furniss, Michael J., Li, Yi, Green, Adam G., Green, Carol E., Iyer, Lalitha V., Bradford, Wallace W., Kapetanovic, Izet M.

“…Resveratrol (trans‐resveratrol, trans‐3,5,4′‐trihydroxystilbene) is a naturally occurring stilbene analogue found in high concentrations in red wine. There is…”
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Glucuronidation of 1′-Hydroxyestragole (1′-HE) by Human UDP-Glucuronosyltransferases UGT2B7 and UGT1A9 by Iyer, Lalitha V., Ho, Mark N., Shinn, Walter M., Bradford, Wallace W., Tanga, Mary J., Nath, Shirley S., Green, Carol E.

“…Estragole (4-allyl-1-methoxybenzene) is a naturally occurring food flavoring agent found in basil, fennel, bay leaves, and other spices. Estragole and its…”
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Pharmacokinetics, Pharmacodynamics and Anti-Tumor Efficacy of PR-171, a Novel Inhibitor of the 20S Proteasome by Kirk, Christopher J., Bennett, Mark K., Buchholz, Tonia J., Demo, Susan D., Ho, Mark N., Jiang, Jing, Laidig, Guy J., Lewis, Evan R., Shenk, Kevin D., Smyth, Mark S., Sun, Congcong M., Vallone, Marcy K., Woo, Tina M., Molineaux, Christopher J.

“…Clinical studies using the boronic acid-based proteasome inhibitor bortezomib (VelcadeTM) have validated the proteasome as a therapeutic intervention point for…”
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