Search Results - "HO, Karen J"

Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease by Gupta, Nilaksh, Buffa, Jennifer A., Roberts, Adam B., Sangwan, Naseer, Skye, Sarah M., Li, Lin, Ho, Karen J., Varga, John, DiDonato, Joseph A., Tang, W.H. Wilson, Hazen, Stanley L.

“…OBJECTIVE:Gut microbial metabolism of dietary choline, a nutrient abundant in a Western diet, produces trimethylamine (TMA) and the atherothrombosis- and…”
Get full text

Diagnosis, classification, and treatment of femoropopliteal artery in-stent restenosis by Ho, Karen J., MD, Owens, Christopher D., MD, MSc

“…In-stent restenosis is a pervasive challenge to the durability of stenting for the treatment of lower extremity ischemia. There is considerable controversy…”
Get full text

Trimethylamine N-oxide: a meta-organismal axis linking the gut and fibrosis by Jang, Jae Woong, Capaldi, Emma, Smith, Tracy, Verma, Priyanka, Varga, John, Ho, Karen J

“…Tissue fibrosis is a common pathway to failure in many organ systems and is the cellular and molecular driver of myriad chronic diseases that are incompletely…”
Get full text

Outcomes of Thoracic Endovascular Aortic Repair and Subclavian Revascularization Techniques by Zamor, Kimberly C., MD, Eskandari, Mark K., MD, FACS, Rodriguez, Heron E., MD, FACS, Ho, Karen J., MD, Morasch, Mark D., MD, FACS, Hoel, Andrew W., MD

“…Background Practice guidelines for management of the left subclavian artery (LSA) during thoracic endovascular aortic repair (TEVAR) are based on low-quality…”
Get full text

Risk prediction of 30-day readmission after infrainguinal bypass for critical limb ischemia by McPhee, James T., MD, Nguyen, Louis L., MD, MBA, MPH, Ho, Karen J., MD, Ozaki, C. Keith, MD, Conte, Michael S., MD, Belkin, Michael, MD

“…Objective Hospital readmission after lower extremity bypass is a large cost burden and has become a focal point for policy change directed at disease-specific…”
Get full text

Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial by McDermott, Mary M., Martens, Christopher R., Domanchuk, Kathryn J., Zhang, Dongxue, Peek, Clara B., Criqui, Michael H., Ferrucci, Luigi, Greenland, Philip, Guralnik, Jack M., Ho, Karen J., Kibbe, Melina R., Kosmac, Kate, Lloyd-Jones, Donald, Peterson, Charlotte A., Sufit, Robert, Tian, Lu, Wohlgemuth, Stephanie, Zhao, Lihui, Zhu, Pei, Leeuwenburgh, Christiaan

“…People with lower extremity peripheral artery disease (PAD) have increased oxidative stress, impaired mitochondrial activity, and poor walking performance…”
Get full text

Publisher Correction: Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial by McDermott, Mary M., Martens, Christopher R., Domanchuk, Kathryn J., Zhang, Dongxue, Peek, Clara B., Criqui, Michael H., Ferrucci, Luigi, Greenland, Philip, Guralnik, Jack M., Ho, Karen J., Kibbe, Melina R., Kosmac, Kate, Lloyd-Jones, Donald, Peterson, Charlotte A., Sufit, Robert, Tian, Lu, Wohlgemuth, Stephanie, Zhao, Lihui, Zhu, Pei, Leeuwenburgh, Christiaan

Get full text

Predictive factors of 30-day unplanned readmission after lower extremity bypass by McPhee, James T., MD, Barshes, Neal R., MD, MPH, Ho, Karen J., MD, Madenci, Arin, MS, MPH, Ozaki, C. Keith, MD, Nguyen, Louis L., MD, MBA, MPH, Belkin, Michael, MD

“…Background Thirty-day unplanned readmission after lower extremity bypass represents a large cost burden and is a logical target for cost-containment…”
Get full text

Microbiota control acute arterial inflammation and neointimal hyperplasia development after arterial injury by Wun, Kelly, Theriault, Betty R, Pierre, Joseph F, Chen, Edmund B, Leone, Vanessa A, Harris, Katharine G, Xiong, Liqun, Jiang, Qun, Spedale, Melanie, Eskandari, Owen M, Chang, Eugene B, Ho, Karen J

“…The microbiome has a functional role in a number of inflammatory processes and disease states. While neointimal hyperplasia development has been linked to…”
Get full text

Microbe-Derived Butyrate and Its Receptor, Free Fatty Acid Receptor 3, But Not Free Fatty Acid Receptor 2, Mitigate Neointimal Hyperplasia Susceptibility After Arterial Injury by Nooromid, Michael, Chen, Edmund B, Xiong, Liqun, Shapiro, Katherine, Jiang, Qun, Demsas, Falen, Eskandari, Maeve, Priyadarshini, Medha, Chang, Eugene B, Layden, Brian T, Ho, Karen J

“…Background Arterial restenosis after vascular surgery is a common cause of midterm restenosis and treatment failure. Herein, we aim to investigate the role of…”
Get full text

Plasma Gut Microbe-Derived Metabolites Associated with Peripheral Artery Disease and Major Adverse Cardiac Events by Ho, Karen J, Ramirez, Joel L, Kulkarni, Rohan, Harris, Katharine G, Helenowski, Irene, Xiong, Liqun, Ozaki, C Keith, Grenon, S Marlene

“…Cardiovascular diseases are associated with gut dysbiosis, but the role of microbe-derived metabolites as biomarkers or modulators of cardiovascular disease…”
Get full text

Open aortic septectomy for complicated type B aortic dissection by Lysak, Nicholas, Vavra, Ashley K., Ho, Karen J.

“…Malperfusion is a complication of acute aortic dissection associated with substantially increased morbidity and mortality. Although endovascular treatment of…”
Get full text

Refinement of survival prediction in patients undergoing lower extremity bypass surgery: Stratification by chronic kidney disease classification by Owens, Christopher D., MD, Ho, Karen J., MD, Kim, Sang, BS, Schanzer, Andres, MD, Lin, Julie, MD, MPH, Matros, Evan, MD, Belkin, Michael, MD, Conte, Michael S., MD

“…Objective End-stage renal disease (ESRD) imparts a significant survival disadvantage to individuals undergoing lower extremity revascularization; however, the…”
Get full text

Inflammatory Cell Dynamics after Murine Femoral Artery Wire Injury: A Multi-Parameter Flow Cytometry-Based Analysis by Pamulapati, Vivek, Cuda, Carla M, Smith, Tracy L, Jung, Jonathan, Xiong, Liqun, Swaminathan, Suchitra, Ho, Karen J

“…An acute inflammatory response following arterial surgery for atherosclerosis, such as balloon angioplasty, stenting, and surgical bypass, is an important…”
Get full text

Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation by Kim, Seok-Jo, Bale, Swarna, Verma, Priyanka, Wan, Qianqian, Ma, Feiyang, Gudjonsson, Johann E., Hazen, Stanley L., Harms, Paul W., Tsou, Pei-Suen, Khanna, Dinesh, Tsoi, Lam C., Gupta, Nilaksh, Ho, Karen J., Varga, John

“…Intestinal dysbiosis is prominent in systemic sclerosis (SSc), but it remains unknown how it contributes to microvascular injury and fibrosis that are…”
Get full text

High dose-rate brachytherapy for the treatment of lower extremity in-stent restenosis by Ho, Karen J., MD, Devlin, Phillip M., MD, Madenci, Arin L., MD, MPH, Semel, Marcus E., MD, MPH, Gravereaux, Edwin C., MD, Nguyen, Louis L., MD, MPH, MBA, Belkin, Michael, MD, Menard, Matthew T., MD

“…Abstract Objective Historically, edge stenosis and late thrombosis limited the effectiveness of adjunctive endovascular brachytherapy (EVBT) for in-stent…”
Get full text

Contemporary predictors of extended postoperative hospital length of stay after carotid endarterectomy by Ho, Karen J., MD, Madenci, Arin L., MD, MPH, McPhee, James T., MD, Semel, Marcus E., MD, MPH, Bafford, Richard A., MD, MPH, Nguyen, Louis L., MD, MPH, MBA, Ozaki, C. Keith, MD, Belkin, Michael, MD

“…Introduction Hospital length of stay (LOS) contributes to costs. Carotid endarterectomy (CEA) is performed frequently by vascular surgeons, making contemporary…”
Get full text

Predictors and consequences of unplanned hospital readmission within 30 days of carotid endarterectomy by Ho, Karen J., MD, Madenci, Arin L., MD, MPH, Semel, Marcus E., MD, MPH, McPhee, James T., MD, Nguyen, Louis L., MD, MPH, MBA, Ozaki, C. Keith, MD, Belkin, Michael, MD

“…Objective In the United States, vascular surgeons frequently perform carotid endarterectomy (CEA). Given the resource burden of unplanned readmission (URA), we…”
Get full text

Microbial Colonization of Germ-Free Mice Restores Neointimal Hyperplasia Development After Arterial Injury by Chen, Edmund B, Shapiro, Katherine E, Wun, Kelly, Kuntz, Thomas, Theriault, Betty R, Nooromid, Michael J, Leone, Vanessa A, Harris, Katharine G, Jiang, Qun, Spedale, Melanie, Xiong, Liqun, Gilbert, Jack A, Chang, Eugene B, Ho, Karen J

“…Background The potential role of the gut microbiome in cardiovascular diseases is increasingly evident. Arterial restenosis attributable to neointimal…”
Get full text

Nonnuclear Actions of Estrogen by Ho, Karen J, Liao, James K

“…ABSTRACT—Estrogen has long been observed to endow cardiovascular protective effects, as evidenced by sex-specific differences in the incidence of hypertensive…”
Get full text