Search Results - "HITMAN, Graham"

Nutritional manipulation for the primary prevention of gestational diabetes mellitus: a meta-analysis of randomised studies by Rogozińska, Ewelina, Chamillard, Monica, Hitman, Graham A, Khan, Khalid S, Thangaratinam, Shakila

“…The rise in gestational diabetes (GDM), defined as first onset or diagnosis of diabetes in pregnancy, is a global problem. GDM is often associated with…”
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Mediterranean-style diet in pregnant women with metabolic risk factors (ESTEEM): A pragmatic multicentre randomised trial by H Al Wattar, Bassel, Dodds, Julie, Placzek, Anna, Beresford, Lee, Spyreli, Eleni, Moore, Amanda, Gonzalez Carreras, Francisco J, Austin, Frances, Murugesu, Nilaani, Roseboom, Tessa J, Bes-Rastrollo, Maira, Hitman, Graham A, Hooper, Richard, Khan, Khalid S, Thangaratinam, Shakila

“…Pregnant women with metabolic risk factors are at high risk of complications. We aimed to assess whether a Mediterranean-style diet reduces adverse pregnancy…”
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Quantification of the type 2 diabetes risk in women with gestational diabetes: a systematic review and meta-analysis of 95,750 women by Rayanagoudar, Girish, Hashi, Amal A., Zamora, Javier, Khan, Khalid S., Hitman, Graham A., Thangaratinam, Shakila

“…Aims/hypothesis Women with gestational diabetes mellitus (GDM) are at risk of developing type 2 diabetes, but individualised risk estimates are unknown. We…”
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Bayesian networks in healthcare: Distribution by medical condition by McLachlan, Scott, Dube, Kudakwashe, Hitman, Graham A, Fenton, Norman E, Kyrimi, Evangelia

“…•A review which identifies the medical conditions for which contemporary literature on Bayesian networks (BNs) have been focused.•Finds that most attention has…”
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Maternal gestational diabetes is associated with genome-wide DNA methylation variation in placenta and cord blood of exposed offspring by Finer, Sarah, Mathews, Chris, Lowe, Rob, Smart, Melissa, Hillman, Sara, Foo, Lin, Sinha, Ajay, Williams, David, Rakyan, Vardhman K, Hitman, Graham A

“…Exposure of a developing foetus to maternal gestational diabetes (GDM) has been shown to programme future risk of diabetes and obesity. Epigenetic variation in…”
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Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus by Bell, Christopher G, Finer, Sarah, Lindgren, Cecilia M, Wilson, Gareth A, Rakyan, Vardhman K, Teschendorff, Andrew E, Akan, Pelin, Stupka, Elia, Down, Thomas A, Prokopenko, Inga, Morison, Ian M, Mill, Jonathan, Pidsley, Ruth, Deloukas, Panos, Frayling, Timothy M, Hattersley, Andrew T, McCarthy, Mark I, Beck, Stephan, Hitman, Graham A

“…Recent multi-dimensional approaches to the study of complex disease have revealed powerful insights into how genetic and epigenetic factors may underlie their…”
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Genetic determinants of serum 25-hydroxyvitamin D concentration during pregnancy and type 1 diabetes in the child by Miettinen, Maija E, Smart, Melissa C, Kinnunen, Leena, Harjutsalo, Valma, Reinert-Hartwall, Linnea, Ylivinkka, Irene, Surcel, Heljä-Marja, Lamberg-Allardt, Christel, Hitman, Graham A, Tuomilehto, Jaakko

“…The in utero environment plays an important role in shaping development and later life health of the fetus. It has been shown that maternal genetic factors in…”
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Very Low Levels of Atherogenic Lipoproteins and the Risk for Cardiovascular Events: A Meta-Analysis of Statin Trials by BOEKHOLDT, S. Matthijs, HOVINGH, G. Kees, KEECH, Antony C, COLQUHOUN, David, HITMAN, Graham A, BETTERIDGE, D. John, CLEARFIELD, Michael B, DOWNS, John R, COLHOUN, Helen M, GOTTO, Antonio M, RIDKER, Paul M, GRUNDY, Scott M, MORA, Samia, KASTELEIN, John J. P, ARSENAULT, Benoit J, AMARENCO, Pierre, PEDERSEN, Terje R, LAROSA, John C, WATERS, David D, DEMICCO, David A, SIMES, R. John

“…Levels of atherogenic lipoproteins achieved with statin therapy are highly variable, but the consequence of this variability for cardiovascular disease risk is…”
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Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks (CLARITY): a multicentre, single-blinded, randomised, controlled, phase 2b, non-inferiority trial by Sivaprasad, Sobha, Prof, Prevost, A Toby, Prof, Vasconcelos, Joana C, MSc, Riddell, Amy, PhD, Murphy, Caroline, MS, Kelly, Joanna, MSc, Bainbridge, James, Prof, Tudor-Edwards, Rhiannon, Prof, Hopkins, David, FRCP, Hykin, Philip, FRCOphth

“…Summary Background Proliferative diabetic retinopathy is the most common cause of severe sight impairment in people with diabetes. Proliferative diabetic…”
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Association of LDL Cholesterol, Non–HDL Cholesterol, and Apolipoprotein B Levels With Risk of Cardiovascular Events Among Patients Treated With Statins: A Meta-analysis by Boekholdt, S. Matthijs, Arsenault, Benoit J, Mora, Samia, Pedersen, Terje R, LaRosa, John C, Nestel, Paul J, Simes, R. John, Durrington, Paul, Hitman, Graham A, Welch, K. M. A, DeMicco, David A, Zwinderman, Aeilko H, Clearfield, Michael B, Downs, John R, Tonkin, Andrew M, Colhoun, Helen M, Gotto, Antonio M, Ridker, Paul M, Kastelein, John J. P

“…CONTEXT The associations of low-density lipoprotein cholesterol (LDL-C), non–high-density lipoprotein cholesterol (non–HDL-C), and apolipoprotein B (apoB)…”
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Effects of Atorvastatin on Kidney Outcomes and Cardiovascular Disease in Patients With Diabetes: An Analysis From the Collaborative Atorvastatin Diabetes Study (CARDS) by Colhoun, Helen M., MD, Betteridge, D. John, PhD, Durrington, Paul N., MD, Hitman, Graham A., MD, Neil, H. Andrew W., DSc, Livingstone, Shona J., MSc, Charlton-Menys, Valentine, PhD, DeMicco, David A., PharmD, Fuller, John H., FRCP

“…Background We examined whether atorvastatin affects diabetic kidney disease and whether the effect of atorvastatin on cardiovascular disease (CVD) varies by…”
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Differential Effects of Oral Boluses of Vitamin D2 vs Vitamin D3 on Vitamin D Metabolism: A Randomized Controlled Trial by Martineau, Adrian R, Thummel, Kenneth E, Wang, Zhican, Jolliffe, David A, Boucher, Barbara J, Griffin, Simon J, Forouhi, Nita G, Hitman, Graham A

“…Vitamin D2 and vitamin D3 have been hypothesized to exert differential effects on vitamin D metabolism. To compare the influence of administering vitamin D2 vs…”
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Socio-cultural influences on the behaviour of South Asian women with diabetes in pregnancy: qualitative study using a multi-level theoretical approach by Greenhalgh, Trisha, Clinch, Megan, Afsar, Nur, Choudhury, Yasmin, Sudra, Rita, Campbell-Richards, Desirée, Claydon, Anne, Hitman, Graham A, Hanson, Philippa, Finer, Sarah

“…Diabetes in pregnancy is common in South Asians, especially those from low-income backgrounds, and leads to short-term morbidity and longer-term metabolic…”
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mHealth apps for gestational diabetes mellitus that provide clinical decision support or artificial intelligence: A scoping review by Daley, Bridget J., Ni’Man, Michael, Neves, Mariana R., Bobby Huda, Mohammed S., Marsh, William, Fenton, Norman E., Hitman, Graham A., McLachlan, Scott

“…Aims Gestational diabetes (GDM) is the most common metabolic disorder of pregnancy, requiring complex management and empowerment of those affected. Mobile…”
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Levels and Changes of HDL Cholesterol and Apolipoprotein A-I in Relation to Risk of Cardiovascular Events Among Statin-Treated Patients: A Meta-Analysis by Boekholdt, S. Matthijs, Arsenault, Benoit J., Hovingh, G. Kees, Mora, Samia, Pedersen, Terje R., LaRosa, John C., Welch, K.M.A., Amarenco, Pierre, DeMicco, David A., Tonkin, Andrew M., Sullivan, David R., Kirby, Adrienne, Colhoun, Helen M., Hitman, Graham A., Betteridge, D. John, Durrington, Paul N., Clearfield, Michael B., Downs, John R., Gotto, Antonio M., Ridker, Paul M., Kastelein, John J.P.

“…BACKGROUND—It is unclear whether levels of high-density lipoprotein cholesterol (HDL-C) or apolipoprotein A-I (apoA-I) remain inversely associated with…”
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Towards standardisation of evidence-based clinical care process specifications by McLachlan, Scott, Kyrimi, Evangelia, Dube, Kudakwashe, Hitman, Graham, Simmonds, Jennifer, Fenton, Norman

“…There is a strong push towards standardisation of treatment approaches, care processes and documentation of clinical practice. However, confusion persists…”
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Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity by Frayling, Timothy M, Timpson, Nicholas J, Weedon, Michael N, Zeggini, Eleftheria, Freathy, Rachel M, Lindgren, Cecilia M, Perry, John R.B, Elliott, Katherine S, Lango, Hana, Rayner, Nigel W, Shields, Beverley, Harries, Lorna W, Barrett, Jeffrey C, Ellard, Sian, Groves, Christopher J, Knight, Bridget, Patch, Ann-Marie, Ness, Andrew R, Ebrahim, Shah, Lawlor, Debbie A, Ring, Susan M, Ben-Shlomo, Yoav, Jarvelin, Marjo-Riitta, Sovio, Ulla, Bennett, Amanda J, Melzer, David, Ferrucci, Luigi, Loos, Ruth J.F, Barroso, Inês, Wareham, Nicholas J, Karpe, Fredrik, Owen, Katharine R, Cardon, Lon R, Walker, Mark, Hitman, Graham A, Palmer, Colin N.A, Doney, Alex S.F, Morris, Andrew D, Smith, George Davey, Hattersley, Andrew T, McCarthy, Mark I

“…Obesity is a serious international health problem that increases the risk of several common diseases. The genetic factors predisposing to obesity are poorly…”
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Effect of Vitamin D Supplementation on Markers of Vascular Function: A Systematic Review and Individual Participant Meta‐Analysis by Beveridge, Louise A., Khan, Faisel, Struthers, Allan D., Armitage, Jane, Barchetta, Ilaria, Bressendorff, Iain, Cavallo, Maria Gisella, Clarke, Robert, Dalan, Rinkoo, Dreyer, Gavin, Gepner, Adam D., Forouhi, Nita G., Harris, Ryan A., Hitman, Graham A., Larsen, Thomas, Khadgawat, Rajesh, Marckmann, Peter, Mose, Frank H., Pilz, Stefan, Scholze, Alexandra, Shargorodsky, Marina, Sokol, Seth I., Stricker, Hans, Zoccali, Carmine, Witham, Miles D.

“…Background Low 25‐hydroxyvitamin D levels are associated with an increased risk of cardiovascular events, but the effect of vitamin D supplementation on…”
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An integrative epi-transcriptomic approach identifies the human cartilage chitinase 3-like protein 2 (CHI3L2) as a potential mediator of B12 deficiency in adipocytes by Ogunkolade, B. William, Adaikalakoteswari, Antonysunil, Cardoso, Shirleny Romualdo, Lowe, Rob, Patel, Nisha, Rakyan, Vardhman, Finer, Sarah, Wabitsch, Martin, Saravanan, Ponnusamy, Tripathi, Gyanendra, Bochukova, Elena, Hitman, Graham A

“…Vitamin B12 has multiple biochemical functions including in the one-carbon cycle generating a methyl group for DNA methylation, and metabolism of fatty acids…”
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Maternal BMI and nutritional status in early pregnancy and its impact on neonatal outcomes at birth in Bangladesh by Bhowmik, Bishwajit, Siddique, Tasnima, Majumder, Anindita, Mdala, Ibrahimu, Hossain, Israt A, Hassan, Zahid, Jahan, Ishrat, Moreira, Nayla Cristina do V, Alim, Abdul, Basit, Abdul, Hitman, Graham A, Khan, Abul Kalam A, Hussain, Akhtar

“…To assess the maternal characteristics and nutritional status according to body mass index (BMI) at 6-14 weeks of gestation and to examine the relationship…”
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