Search Results - "HIRSCH, K."
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Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets
Published in Chemical Society reviews (21-04-2015)“…Dynamic combinatorial chemistry (DCC) has emerged as a powerful strategy to identify ligands for biological targets given that it enables the target to direct…”
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2
Molecular Biodynamers: Dynamic Covalent Analogues of Biopolymers
Published in Accounts of chemical research (21-02-2017)“…Constitutional dynamic chemistry (CDC) features the use of reversible linkages at both molecular and supramolecular levels, including reversible covalent bonds…”
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3
Examining the Factor Structure of the Self-Compassion Scale in 20 Diverse Samples: Support for Use of a Total Score and Six Subscale Scores
Published in Psychological assessment (01-01-2019)“…This study examined the factor structure of the Self-Compassion Scale (SCS) using secondary data drawn from 20 samples (N = 11,685)-7 English and 13…”
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4
Self-Compassion, Stress, and Coping in the Context of Chronic Illness
Published in Self and identity (04-05-2015)“…A recent review suggested that self-compassion promotes use of adaptive rather than maladaptive coping. Less is known about how self-compassion is linked to…”
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5
Development of Inhibitors of the 2C‑Methyl‑d‑erythritol 4‑Phosphate (MEP) Pathway Enzymes as Potential Anti-Infective Agents
Published in Journal of medicinal chemistry (11-12-2014)“…Important pathogens such as Mycobacterium tuberculosis and Plasmodium falciparum, the causative agents of tuberculosis and malaria, respectively, and plants,…”
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6
Spin and orbital magnetic moments of size-selected iron, cobalt, and nickel clusters
Published in Physical review. B, Condensed matter and materials physics (19-11-2014)“…Spin and orbital magnetic moments of cationic iron, cobalt, and nickel clusters have been determined from x-ray magnetic circular dichroism spectroscopy. In…”
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7
Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain
Published in Nature communications (05-08-2024)“…Plasmodium falciparum is the main causative agent of malaria, a deadly disease that mainly affects children under five years old. Artemisinin-based combination…”
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Integrating norms into the logic of energy and environmental policymaking
Published in Energy research & social science (01-11-2022)“…Norms play a powerful role in shaping behaviors like energy consumption and adoption of clean energy technologies. Interventions that specifically target norm…”
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COVID-19 vaccine effectiveness in adults with developmental disabilities living in group homes
Published in Public health (London) (01-08-2022)Get full text
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10
The Structure of the First Coordination Shell in Liquid Water
Published in Science (American Association for the Advancement of Science) (14-05-2004)“…X-ray absorption spectroscopy and x-ray Raman scattering were used to probe the molecular arrangement in the first coordination shell of liquid water. The…”
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From Wood to Tetrahydro-2-benzazepines in Three Waste-Free Steps: Modular Synthesis of Biologically Active Lignin-Derived Scaffolds
Published in ACS central science (23-10-2019)“…Inherently complex, lignin-derived aromatic monomers comprising valuable structural moieties present in many pharmaceuticals would serve as ideal substrates…”
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12
Phosphate Recognition in Structural Biology
Published in Angewandte Chemie International Edition (01-01-2007)“…Drug‐discovery research in the past decade has seen an increased selection of targets with phosphate recognition sites, such as protein kinases and…”
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13
Spin coupling and orbital angular momentum quenching in free iron clusters
Published in Physical review letters (30-01-2012)“…Magnetic spin and orbital moments of size-selected free iron cluster ions Fe{n}{+} (n=3-20) have been determined via x-ray magnetic circular dichroism…”
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14
Abuse of tropicamide eye drops: review of clinical data
Published in Revista brasileira de psiquiatria (01-10-2022)“…Over the past 15 years, the increasing nonmedical use of tropicamide ophthalmic drops has been reported in Europe, coinciding with an increase in opioid…”
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15
Thermoresponsive cholesteric liquid–crystal systems doped with terpenoids as drug delivery systems for skin applications
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2023)“…[Display omitted] Stimuli-responsive and tunable soft-matter systems are an advanced class of materials applicable for drug delivery. Liquid crystals (LCs) are…”
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Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery
Published in Angewandte Chemie International Edition (22-01-2024)“…Deriving active pharmaceutical agents from renewable resources is crucial to increasing the economic feasibility of modern biorefineries and promises to…”
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17
Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling
Published in The FASEB journal (01-01-2020)“…For protection from inhaled pathogens many strategies have evolved in the airways such as mucociliary clearance and cough. We have previously shown that…”
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N‑Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases
Published in Journal of medicinal chemistry (13-08-2020)“…In light of the global antimicrobial-resistance crisis, there is an urgent need for novel bacterial targets and antibiotics with novel modes of action. It has…”
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Targeting Extracellular Bacterial Proteases for the Development of Novel Antivirulence Agents
Published in Chimia (25-05-2022)“…As resistance to clinically available antibiotics persistently increases, applying new strategies to target pathogenic bacteria are paramount to design…”
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Correction: Fries et al. Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin A Using a Staphylococcus aureus Infection Model in Zebrafish Embryos. Int. J. Mol. Sci. 2023, 24 , 12791
Published in International journal of molecular sciences (07-02-2024)“…The authors would like to make the following corrections to the original publication [...]…”
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