Search Results - "HIROSE Michiko"
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Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs
Published in Nature cell biology (01-09-2021)“…PIWI-interacting RNAs (piRNAs) support the germline by suppressing retrotransposons. Studies of the pathway in mice have strongly shaped the view that…”
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2
Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas
Published in Nature communications (01-05-2020)“…Somatic cell nuclear transfer (SCNT) in mammals is an inefficient process that is frequently associated with abnormal phenotypes, especially in placentas…”
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3
Editing the Genome of the Golden Hamster (Mesocricetus auratus)
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…The golden (Syrian) hamster (Mesocricetus auratus) is a small rodent belonging to the Cricetidae family. Golden hamsters have several unique characteristics…”
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4
Acrosin is essential for sperm penetration through the zona pellucida in hamsters
Published in Proceedings of the National Academy of Sciences - PNAS (04-02-2020)“…During natural fertilization, mammalian spermatozoa must pass through the zona pellucida before reaching the plasma membrane of the oocyte. It is assumed that…”
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The golden (Syrian) hamster as a model for the study of reproductive biology: Past, present, and future
Published in Reproductive medicine and biology (01-01-2019)“…Background The golden (Syrian) hamster (Mesocricetus auratus) is a small rodent that belongs to the Cricetidae family. It has several unique features that are…”
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6
Derivation of embryonic stem cells from wild-derived mouse strains by nuclear transfer using peripheral blood cells
Published in Scientific reports (10-07-2023)“…Wild-derived mouse strains have been extensively used in biomedical research because of the high level of inter-strain polymorphisms and phenotypic variations…”
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7
Obox4 promotes zygotic genome activation upon loss of Dux
Published in eLife (24-06-2024)“…Once fertilized, mouse zygotes rapidly proceed to zygotic genome activation (ZGA), during which long terminal repeats (LTRs) of murine endogenous retroviruses…”
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Maintenance of mouse trophoblast stem cells in KSR-based medium allows conventional 3D culture
Published in Journal of Reproduction and Development (01-01-2021)“…Mouse trophoblast stem cells (TSCs) can differentiate into trophoblast cells, which constitute the placenta. Under conventional culture conditions, in a medium…”
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9
The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development
Published in Cell reports (Cambridge) (02-05-2017)“…MicroRNAs (miRNAs) represent small noncoding RNAs that are involved in physiological and developmental processes by posttranscriptionally inhibiting gene…”
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10
Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells
Published in Genes & development (01-01-2022)“…The placenta is a highly evolved, specialized organ in mammals. It differs from other organs in that it functions only for fetal maintenance during gestation…”
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11
Single-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas9
Published in Experimental Animals (01-01-2015)“…Targeted genome editing of nonrodent mammalian species has provided the potential for highly accurate interventions into gene function in humans and the…”
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12
Disruption of insulin receptor substrate 2 (IRS2) causes non-obese type 2 diabetes with β-cell dysfunction in the golden (Syrian) hamster
Published in Scientific reports (12-08-2024)“…Because of the advent of genome-editing technology, gene knockout (KO) hamsters have become attractive research models for diverse diseases in humans. This…”
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13
Regulation of pluripotency in male germline stem cells by Dmrt1
Published in Genes & development (15-09-2013)“…Spermatogonial stem cells (SSCs) present the potential to acquire pluripotency under specific culture conditions. However, the frequency of pluripotent cell…”
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14
Histone H3 Methylated at Arginine 17 Is Essential for Reprogramming the Paternal Genome in Zygotes
Published in Cell reports (Cambridge) (19-09-2017)“…At fertilization, the paternal genome undergoes extensive reprogramming through protamine-histone exchange and active DNA demethylation, but only a few…”
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15
Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression
Published in Experimental Animals (01-01-2024)“…Allele-specific monoallelic gene expression is a unique phenomenon and a great resource for analyzing gene regulation. To study this phenomenon, we established…”
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16
Naive-like Conversion Overcomes the Limited Differentiation Capacity of Induced Pluripotent Stem Cells
Published in The Journal of biological chemistry (06-09-2013)“…Although induced pluripotent stem (iPS) cells are indistinguishable from ES cells in their expression of pluripotent markers, their differentiation into…”
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Efficient and scheduled production of pseudopregnant female mice for embryo transfer by estrous cycle synchronization
Published in Journal of Reproduction and Development (2017)“…In embryo transfer experiments in mice, pseudopregnant females as recipients are prepared by sterile mating with vasectomized males. Because only females at…”
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Aberrant imprinting in mouse trophoblast stem cells established from somatic cell nuclear transfer-derived embryos
Published in Epigenetics (03-07-2018)“…Although phenotypic abnormalities frequently appear in the placenta following somatic cell nuclear transfer (SCNT), mouse trophoblast stem cells (TSCs)…”
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19
Isolation, characterization, and in vitro and in vivo differentiation of putative thecal stem cells
Published in Proceedings of the National Academy of Sciences - PNAS (24-07-2007)“…Although ovarian theca cells play an indispensable role in folliculogenesis by providing follicular structural integrity and steroid substrates for estrogen…”
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A simple and robust method for establishing homogeneous mouse epiblast stem cell lines by wnt inhibition
Published in Stem cell reports (14-04-2015)“…Epiblast stem cells (EpiSCs) are pluripotent stem cells derived from epiblasts of postimplantation mouse embryos, and thus provide a useful model for studying…”
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