Search Results - "HIRATA, Kazumasa"

AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells by Ueda, Yuko, Ooshio, Ikumi, Fusamae, Yasuyuki, Kitae, Kaori, Kawaguchi, Megumi, Jingushi, Kentaro, Hase, Hiroaki, Harada, Kazuo, Hirata, Kazumasa, Tsujikawa, Kazutake

“…The mammalian AlkB homolog (ALKBH) family of proteins possess a 2-oxoglutarate- and Fe(II)-dependent oxygenase domain. A similar domain in the Escherichia coli…”
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The Model Core Curriculum for Pharmacy Education to Become a Pharmacist with a 20-year Perspective on Human Resources Development by Hirata, Kazumasa, Suzuki, Tadashi

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Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes by Takayama, Kazuo, Morisaki, Yuta, Kuno, Shuichi, Nagamoto, Yasuhito, Harada, Kazuo, Furukawa, Norihisa, Ohtaka, Manami, Nishimura, Ken, Imagawa, Kazuo, Sakurai, Fuminori, Tachibana, Masashi, Sumazaki, Ryo, Noguchi, Emiko, Nakanishi, Mahito, Hirata, Kazumasa, Kawabata, Kenji, Mizuguchi, Hiroyuki

“…Interindividual differences in hepatic metabolism, which are mainly due to genetic polymorphism in its gene, have a large influence on individual drug efficacy…”
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Paper-based colorimetric biosensor for antibiotics inhibiting bacterial protein synthesis by Duyen, Tran Thi My, Matsuura, Hideyuki, Ujiie, Kazuki, Muraoka, Misa, Harada, Kazuo, Hirata, Kazumasa

“…Due to the presence of antibiotics in environmental water and their potential influence on the occurrence of antibiotic-resistant bacteria, development of a…”
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Mycobacterium smegmatis alters the production of secondary metabolites by marine-derived Aspergillus niger by Jomori, Takahiro, Hara, Yasumasa, Sasaoka, Miho, Harada, Kazuo, Setiawan, Andi, Hirata, Kazumasa, Kimishima, Atsushi, Arai, Masayoshi

“…It is generally accepted that fungi have a number of dormant gene clusters for the synthesis of secondary metabolites, and the activation of these gene…”
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Gamma-Glutamylcysteine Production Using Phytochelatin Synthase-Like Enzyme Derived from Nostoc sp. Covalently Immobilized on a Cellulose Carrier by Muraoka, Misa, Ohno, Moeka, Nakai, Takuya, Matsuura, Hideyuki, Nagano, Kazuya, Arai, Masayoshi, Hirata, Yoshihiko, Uyama, Hiroshi, Hirata, Kazumasa

“…Gamma-glutamylcysteine (γ-EC) is an intermediate generated in the de novo synthesis of glutathione (GSH). Recent studies have revealed that the administration…”
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Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies by Negoro, Ryosuke, Takayama, Kazuo, Kawai, Kanae, Harada, Kazuo, Sakurai, Fuminori, Hirata, Kazumasa, Mizuguchi, Hiroyuki

“…The small intestine plays an important role in the absorption and metabolism of oral drugs. In the current evaluation system, it is difficult to predict the…”
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The presence of colistin resistance gene mcr-1 and -3 in ESBL producing Escherichia coli isolated from food in Ho Chi Minh City, Vietnam by Yamaguchi, Takahiro, Kawahara, Ryuji, Harada, Kazuo, Teruya, Shihono, Nakayama, Tatsuya, Motooka, Daisuke, Nakamura, Shota, Nguyen, Phuc Do, Kumeda, Yuko, Van Dang, Chinh, Hirata, Kazumasa, Yamamoto, Yoshimasa

“…Colistin is indicated for the treatment of multidrug-resistant gram-negative bacterial infections. However, the spread of colistin-resistant bacteria…”
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Water metagenomic analysis reveals low bacterial diversity and the presence of antimicrobial residues and resistance genes in a river containing wastewater from backyard aquacultures in the Mekong Delta, Vietnam by Nakayama, Tatsuya, Tuyet Hoa, Tran Thi, Harada, Kazuo, Warisaya, Minae, Asayama, Megumi, Hinenoya, Atsushi, Lee, Joon Won, Phu, Tran Minh, Ueda, Shuhei, Sumimura, Yoshinori, Hirata, Kazumasa, Phuong, Nguyen Thanh, Yamamoto, Yoshimasa

“…The environmental pathways for the dissemination of antibiotic resistance have recently received increased attention. Aquatic environments act as reservoirs or…”
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Optimization of Reaction Conditions for γ-Glutamylcysteine Production from Glutathione Using a Phytochelatin Synthase-Like Enzyme from Nostoc sp. Pasteur Culture Collection 7120 by Muraoka, Misa, Ohno, Moeka, Tateishi, Makoto, Matsuura, Hideyuki, Nagano, Kazuya, Hirata, Yoshihiko, Hirata, Kazumasa

“…γ-Glutamylcysteine (γ-EC) has antioxidant properties similar to those of glutathione (GSH) and acts as its precursor in mammals. There are a few procedures for…”
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Physicians' and Nurses' Perceptions of Pharmacists' Competencies, and Their Needs of Pharmacists during COVID-19 by Mamiya, Kayoko Takeda, Hirata, Kazumasa

“…Objective: To understand how physicians and nurses evaluate Japanese pharmacists’ observed competencies and to explore potential new roles for pharmacists…”
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Comparison of commercially available media for hepatic differentiation and hepatocyte maintenance by Toba, Yukiko, Deguchi, Sayaka, Mimura, Natsumi, Sakamoto, Ayaka, Harada, Kazuo, Hirata, Kazumasa, Takayama, Kazuo, Mizuguchi, Hiroyuki

“…Human hepatocytes are essential materials in pharmaceutical researches. Not only primary human hepatocytes (PHH) but also human iPS cell-derived…”
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Modeling of Hepatic Drug Metabolism and Responses in CYP2C19 Poor Metabolizer Using Genetically Manipulated Human iPS cells by Deguchi, Sayaka, Yamashita, Tomoki, Igai, Keisuke, Harada, Kazuo, Toba, Yukiko, Hirata, Kazumasa, Takayama, Kazuo, Mizuguchi, Hiroyuki

“…Cytochrome P450 family 2 subfamily C member 19 (CYP2C19), in liver, plays important roles in terms of drug metabolism. It is known that CYP2C19 poor…”
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Antibiotic Residue Monitoring Results for Pork, Chicken, and Beef Samples in Vietnam in 2012–2013 by Yamaguchi, Takahiro, Okihashi, Masahiro, Harada, Kazuo, Konishi, Yoshimasa, Uchida, Kotaro, Do, Mai Hoang Ngoc, Bui, Huong Dang Thien, Nguyen, Thinh Duc, Nguyen, Phuc Do, Chau, Vien Van, Dao, Khanh Thi Van, Nguyen, Hue Thi Ngoc, Kajimura, Keiji, Kumeda, Yuko, Bui, Chien Trong, Vien, Mai Quang, Le, Ninh Hoang, Hirata, Kazumasa, Yamamoto, Yoshimasa

“…A monitoring plan of residual antibiotics in food of animal origin was conducted in Vietnam from 2012 to 2013. Meat samples were collected from slaughterhouses…”
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Perspectives of Pharmaceutical Education—While Explaining the Related Evaluation Standards and Their Viewpoints of “Evaluation of Pharmaceutical Education Programs” by Hirata, Kazumasa

“…In 2013, a program to be implemented by the Japan Accreditation Board for Pharmaceutical Education, Third-party Pharmaceutical Education Evaluation, was…”
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Monitoring of Antibiotic Residues in Aquatic Products in Urban and Rural Areas of Vietnam by Uchida, Kotaro, Konishi, Yoshimasa, Harada, Kazuo, Okihashi, Masahiro, Yamaguchi, Takahiro, Do, Mai Hoang Ngoc, Thi Bui, Long, Duc Nguyen, Thinh, Do Nguyen, Phuc, Thi Khong, Diep, Thi Tran, Hoa, Nam Nguyen, Thang, Viet Le, Ha, Van Chau, Vien, Thi Van Dao, Khanh, Thi Ngoc Nguyen, Hue, Kajimura, Keiji, Kumeda, Yuko, Tran Pham, Khanh, Ngoc Pham, Khai, Trong Bui, Chien, Quang Vien, Mai, Hoang Le, Ninh, Van Dang, Chinh, Hirata, Kazumasa, Yamamoto, Yoshimasa

“…Antibiotic residues in aquatic products in Vietnam were investigated. A total of 511 fish and shrimp samples were collected from markets in Ho Chi Minh City…”
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High throughput and exhaustive analysis of diverse lipids by using supercritical fluid chromatography-mass spectrometry for metabolomics by Bamba, Takeshi, Shimonishi, Naruto, Matsubara, Atsuki, Hirata, Kazumasa, Nakazawa, Yoshihisa, Kobayashi, Akio, Fukusaki, Eiichiro

“…We have developed an analytical system that enables the simultaneous rapid analysis of lipids with varied structures and polarities through the use of…”
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Rapid and Easy Multiresidue Method for the Analysis of Antibiotics in Meats by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry by Yamaguchi, Takahiro, Okihashi, Masahiro, Harada, Kazuo, Uchida, Kotaro, Konishi, Yoshimasa, Kajimura, Keiji, Hirata, Kazumasa, Yamamoto, Yoshimasa

“…This study involved the development of a multiresidue method for the rapid analysis of 43 antibiotics in meats using ultrahigh-performance liquid…”
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Optimization and Evaluation of Pretreatment Method for sp-ICP-MS to Reveal the Distribution of Silver Nanoparticles in the Body by Ishizaka, Takuya, Nagano, Kazuya, Tasaki, Ikkei, Tao, Hong, Gao, Jian-Qing, Harada, Kazuo, Hirata, Kazumasa, Saito, Shigeru, Tsujino, Hirofumi, Higashisaka, Kazuma, Tsutsumi, Yasuo

“…The prevalent use of engineered nanoparticles (ENPs) has increased our exposure to these particles. The current available analytical techniques fail to…”
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Generation of Human iPSC–Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction by Takayama, Kazuo, Negoro, Ryosuke, Yamashita, Tomoki, Kawai, Kanae, Ichikawa, Moe, Mori, Takanori, Nakatsu, Noriyuki, Harada, Kazuo, Ito, Sumito, Yamada, Hiroshi, Yamaura, Yoshiyuki, Hirata, Kazumasa, Ishida, Seiichi, Mizuguchi, Hiroyuki

“…Background & aimsTo develop an effective and safe orally administered drug, it is important to predict its intestinal absorption rate, intestinal first-pass…”
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