Search Results - "HIRASHIMA, NAOHIDE"

A Simple Method for Purified Primary Culture of Enteric Glial Cells from Mouse Small Intestine by Teramoto, Hikaru, Hirashima, Naohide, Tanaka, Masahiko

“…Enteric glial cells (EGCs) have been recognized as an important cell type constituting the enteric nervous system. EGCs control intestinal function and…”
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Calcineurin B1 Deficiency in Glial Cells Reduces Gastrointestinal Motility and Results in Maldigestion and/or Malabsorption in Mice by Okura, Umi, Hirashima, Naohide, Tanaka, Masahiko

“…Calcineurin is a Ca2+/calmodulin-dependent protein phosphatase abundantly expressed in the nervous system. To investigate the roles of calcineurin in glial…”
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Receptor dynamics regulates actin polymerization state through phosphorylation of cofilin in mast cells by Suzuki, Ruriko, Inoh, Yoshikazu, Yokawa, Satoru, Furuno, Tadahide, Hirashima, Naohide

“…Aggregation of IgE bound to the high-affinity IgE receptor (FcεRI) by a multivalent antigen induces mast cell activation, while disaggregation of aggregated…”
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Calcineurin B1 Deficiency in Glial Cells Induces Mucosal Degeneration and Inflammation in Mouse Small Intestine by Fujita, Maya, Yagi, Takaki, Okura, Umi, Tanaka, Jun’ichi, Hirashima, Naohide, Tanaka, Masahiko

“…Although calcineurin is abundantly expressed in the nervous system and involved in neurite extension and synaptic plasticity in neurons, little is known about…”
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Expression of the GluA2 subunit of glutamate receptors is required for the normal dendritic differentiation of cerebellar Purkinje cells by Tanaka, Masahiko, Senda, Tomomi, Hirashima, Naohide

“…•Dendritic differentiation was inhibited by GluA2 knockdown in Purkinje cells.•[Ca2+]i elevation was augmented by GluA2 knockdown in Purkinje cells.•GluA2…”
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Calcineurin B1 Deficiency Reduces Proliferation, Increases Apoptosis, and Alters Secretion in Enteric Glial Cells of Mouse Small Intestine in Culture by Teramoto, Hikaru, Hirashima, Naohide, Tanaka, Masahiko

“…To investigate the roles of calcineurin (CN) in glial cells, we previously generated conditional knockout (CKO) mice lacking in glial cells. Because these CKO…”
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Effect of Complexin II on Membrane Fusion between Liposomes Containing Mast Cell SNARE Proteins by Tadokoro, Satoshi, Hirashima, Naohide, Utsunomiya-Tate, Naoko

“…Mast cells are involved in allergic responses and undergo exocytotic release of inflammatory mediators in response to antigen stimulation. Soluble…”
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Surface Plasmon Resonance of Two-Dimensional Gold Colloidal Crystals Formed on Gold Plates by Aoyama, Yurina, Toyotama, Akiko, Okuzono, Tohru, Hirashima, Naohide, Imai, Hiroki, Uchida, Fumio, Takiguchi, Yoshihiro, Yamanaka, Junpei

“…The free electrons inside precious metals such as Au vibrate when the surface of the metal is irradiated with an electromagnetic wave of an appropriate…”
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Effects of PIP2 on membrane fusion between mast cell SNARE liposomes mediated by synaptotagmin 2 by Tadokoro, Satoshi, Inoh, Yoshikazu, Nakanishi, Mamoru, Hirashima, Naohide

“…Recent studies have revealed that SNARE proteins are involved in exocytotic release in mast cells. Previously, we reported that mast cell SNARE proteins induce…”
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The suppression of IgE-mediated histamine release from mast cells following exocytic exclusion of biodegradable polymeric nanoparticles by Tahara, Kohei, Tadokoro, Satoshi, Yamamoto, Hiromitsu, Kawashima, Yoshiaki, Hirashima, Naohide

“…Abstract The objective of this study is to evaluate the effect of polymeric nanoparticles (NPs) on the allergic response of mast cells that release…”
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Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells by Ohashi, Ryo, Sakata, Shin‐ichi, Naito, Asami, Hirashima, Naohide, Tanaka, Masahiko

“…ABSTRACT Cerebellar Purkinje cells have the most elaborate dendritic trees among neurons in the brain. We examined the roles of ryanodine receptor (RyR), an…”
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Mitochondria Take Up Ca2+ in Two Steps Dependently on Store-Operated Ca2+ Entry in Mast Cells by Takekawa, Marie, Furuno, Tadahide, Hirashima, Naohide, Nakanishi, Mamoru

“…The ability of mitochondria to take up Ca2+ has important functional implications for modulation of cellular Ca2+ signaling. Mitochondrial Ca2+ uptake is…”
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Biosurfactant mannosyl-erythritol lipid inhibits secretion of inflammatory mediators from RBL-2H3 cells by Morita, Yosuke, Tadokoro, Satoshi, Sasai, Masao, Kitamoto, Dai, Hirashima, Naohide

“…Biosurfactant mannosyl-erythritol lipids (MELs) are glycolipids produced by microbes that have various biological activities. It has been reported that MELs…”
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Inhibitory effects of a cationic liposome on allergic reaction mediated by mast cell activation by Inoh, Yoshikazu, Tadokoro, Satoshi, Tanabe, Hiroki, Inoue, Makoto, Hirashima, Naohide, Nakanishi, Mamoru, Furuno, Tadahide

“…Several studies have shown that cationic liposomes exert immunomodulatory effects with low immunogenicity and toxicity, and offer advantages such as easy…”
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Transfer of small interfering RNA by single-cell electroporation in cerebellar cell cultures by Tanaka, Masahiko, Yanagawa, Yuchio, Hirashima, Naohide

“…RNA interference (RNAi) is a powerful means to investigate functions of genes involved in neuronal differentiation and degeneration. In contrast to widely used…”
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Rapid delivery of small interfering RNA by biosurfactant MEL-A-containing liposomes by Inoh, Yoshikazu, Furuno, Tadahide, Hirashima, Naohide, Kitamoto, Dai, Nakanishi, Mamoru

“…► We use MEL-A-containing cationic liposomes for siRNA delivery. ► MEL-A-containing cationic liposomes can efficiently and rapidly deliver siRNA into the…”
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Orai-2 is localized on secretory granules and regulates antigen-evoked Ca2+ mobilization and exocytosis in mast cells by Ikeya, Miho, Yamanoue, Kiyoshi, Mochizuki, Yuji, Konishi, Hirofumi, Tadokoro, Satoshi, Tanaka, Masahiko, Suzuki, Ryo, Hirashima, Naohide

“…•We investigated the expression of Orai, a store operated Ca channel in mast cells.•Orai-1 and -2 are major isoforms of Orai expressed in mast cells.•Orai-2 is…”
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Synergistic effect of a biosurfactant and protamine on gene transfection efficiency by Inoh, Yoshikazu, Furuno, Tadahide, Hirashima, Naohide, Kitamoto, Dai, Nakanishi, Mamoru

“…[Display omitted] Several barriers need to be overcome to ensure successful gene transfection, including passing of the foreign gene through the plasma…”
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Detection of asymmetric distribution of phospholipids by fluorescence resonance energy transfer by Nishimura, Yoko, Tadokoro, Satoshi, Tanaka, Masahiko, Hirashima, Naohide

“…► We developed a new method to detect asymmetric distribution of phospholipids. ► The method is based on fluorescence resonance energy transfer (FRET). ► FRET…”
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Optimization of Single-Cell Electroporation Protocol for Forced Gene Expression in Primary Neuronal Cultures by Nishikawa, Shin, Hirashima, Naohide, Tanaka, Masahiko

“…The development and function of the central nervous system (CNS) are realized through interactions between many neurons. To investigate cellular and molecular…”
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