Search Results - "HIRANO, Shigeru"

The Effect of Oxidative Stress on the Human Voice by Hirano, Shigeru, Inufusa, Haruhiko, You, Fukka

“…The vocal fold vibrates in high frequency to create voice sound. The vocal fold has a sophisticated histological "layered structure" that enables such…”
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Intracordal Injection of Basic Fibroblast Growth Factor in 100 Cases of Vocal Fold Atrophy and Scar by Hirano, Shigeru, Sugiyama, Yoichiro, Kaneko, Mami, Mukudai, Shigeyuki, Fuse, Shinya, Hashimoto, Keiko

“…Objectives/Hypothesis Vocal fold atrophy, scar, and sulcus reduce the vibratory function of the vocal fold mucosa, which causes severe refractory dysphonia. We…”
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Prognostic significance of spatial immune profiles in human solid cancers by Tsujikawa, Takahiro, Mitsuda, Junichi, Ogi, Hiroshi, Miyagawa‐Hayashino, Aya, Konishi, Eiichi, Itoh, Kyoko, Hirano, Shigeru

“…Immune‐based tumor characteristics in the context of tumor heterogeneity are associated with suppression as well as promotion of cancer progression in various…”
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Neck Dissections Based on Sentinel Lymph Node Navigation Versus Elective Neck Dissections in Early Oral Cancers: A Randomized, Multicenter, and Noninferiority Trial by Hasegawa, Yasuhisa, Tsukahara, Kiyoaki, Yoshimoto, Seiichi, Miura, Kouki, Yokoyama, Junkichi, Hirano, Shigeru, Uemura, Hirokazu, Sugasawa, Masashi, Yoshizaki, Tomokazu, Homma, Akihiro, Chikamatsu, Kazuaki, Suzuki, Mikio, Shiotani, Akihiro, Matsuzuka, Takashi, Kohno, Naoyuki, Miyazaki, Masakazu, Oze, Isao, Matsuo, Keitaro, Kosuda, Shigeru, Yatabe, Yasushi

“…This study aimed to compare patients with early oral cavity squamous cell carcinoma (OCSCC) (tumor category [T] 1-2, node-negative, and no distant metastasis)…”
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Physiological Effects of Voice Therapy for Aged Vocal Fold Atrophy Revealed by EMG Study by Kaneko, Mami, Sugiyama, Yoichiro, Fuse, Shinya, Mukudai, Shigeyuki, Hirano, Shigeru

“…Age-related voice changes are characterized as breathy, weak and strained, and a deterioration in vocal function in the elderly has been putatively linked to a…”
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Effects of Voice Therapy for Dysphonia due to Tension Imbalance in Unilateral Vocal Fold Paralysis and Paresis by Kaneko, Mami, Sugiyama, Yoichiro, Mukudai, Shigeyuki, Hirano, Shigeru

“…OBJECTIVESMedialization procedures, such as type I thyroplasty, arytenoid adduction, and vocal fold injection, are popular treatments for dysphonia due to…”
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Mechanisms Underlying the Antifibrotic Potential of Estradiol for Vocal Fold Fibrosis by Ozawa, Satomi, Mukudai, Shigeyuki, Sugiyama, Yoichiro, Branski, Ryan C., Hirano, Shigeru

“…Objectives/Hypothesis Vocal fold fibrosis remains a significant clinical challenge. Estrogens, steroid hormones predominantly responsible for secondary sexual…”
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Complementary Effect of Transcutaneous Cervical Stimulation by Interferential Current on Functional Dysphonia by Kaneko, Mami, Sugiyama, Yoichiro, Fuse, Shinya, Mukudai, Shigeyuki, Hirano, Shigeru

“…Functional dysphonia (FD) varies in terms of vocal behavior and treatment efficacy. So-called hypofunctional dysphonia is characterized by insufficient…”
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Supportive effect of interferential current stimulation on susceptibility of swallowing in guinea pigs by Umezaki, Toshiro, Sugiyama, Yoichiro, Fuse, Shinya, Mukudai, Shigeyuki, Hirano, Shigeru

“…Sensory-motor control of the pharyngeal swallow requires sensory afferent inputs from the pharynx and larynx evoked by introducing bolus into the pharynx…”
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Tamoxifen Alters TGF‐β1/Smad Signaling in Vocal Fold Injury by Matsushita, Hiroki, Mukudai, Shigeyuki, Ozawa, Satomi, Kinoshita, Shota, Hashimoto, Keiko, Kaneko, Mami, Sugiyama, Yoichiro, Branski, Ryan C., Hirano, Shigeru

“…Objectives Effective treatments for vocal fold fibrosis remain elusive. Tamoxifen (TAM) is a selective estrogen receptor modulator and was recently reported to…”
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Firing characteristics of swallowing interneurons in the dorsal medulla during physiologically induced swallowing in perfused brainstem preparation in rats by Yamamoto, Ryota, Sugiyama, Yoichiro, Hashimoto, Keiko, Kinoshita, Shota, Takemura, Akiyo, Fuse, Shinya, Kaneko, Mami, Mukudai, Shigeyuki, Umezaki, Toshiro, Dutschmann, Mathias, Nakagawa, Takashi, Hirano, Shigeru

“…[Display omitted] •Activities of swallowing neurons during physiologically evoked swallow were assessed.•About half neurons were inactive without response to…”
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Efficacy of Yokukansan, a traditional Japanese herbal medicine, in patients with dizziness and irritability by Taki, Masakatsu, Hasegawa, Tatsuhisa, Ninoyu, Yuzuru, Hirano, Shigeru

“…Irritability is an emotional stress symptom that causes or exacerbates dizziness. Antidepressants may be helpful for some conditions that are accompanied by…”
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Activity of swallowing‐related neurons in the medulla in the perfused brainstem preparation in rats by Hashimoto, Keiko, Sugiyama, Yoichiro, Fuse, Shinya, Umezaki, Toshiro, Oku, Yoshitaka, Dutschmann, Mathias, Hirano, Shigeru

“…Objectives/Hypothesis We aimed to investigate and validate the cellular activity patterns and the potential topographical organization of neurons of the…”
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Optimal Duration for Voice Rest After Vocal Fold Surgery: Randomized Controlled Clinical Study by Kaneko, Mami, Shiromoto, Osamu, Fujiu-Kurachi, Masako, Kishimoto, Yo, Tateya, Ichiro, Hirano, Shigeru

“…Summary Objectives Voice rest is commonly recommended after phonomicrosurgery to prevent worsening of vocal fold injuries. However, the most effective duration…”
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Multidimensional Analysis on the Effect of Vocal Function Exercises on Aged Vocal Fold Atrophy by Kaneko, Mami, Hirano, Shigeru, Tateya, Ichiro, Kishimoto, Yo, Hiwatashi, Nao, Fujiu-Kurachi, Masako, Ito, Juichi

“…Summary Objectives Age-related voice change is characterized as weak, harsh, and breathy. These changes are caused by histologic alteration of the lamina…”
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Influences of GABAergic Inhibition in the Dorsal Medulla on Contralateral Swallowing Neurons in Rats by Kinoshita, Shota, Sugiyama, Yoichiro, Hashimoto, Keiko, Fuse, Shinya, Mukudai, Shigeyuki, Umezaki, Toshiro, Dutschmann, Mathias, Hirano, Shigeru

“…Objectives We aimed to examine the effect of unilateral inhibition of the medullary dorsal swallowing networks on the activities of swallowing‐related cranial…”
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Anti-inflammatory and Antioxidant Effects of Japanese Herbal Medicine Kyoseihatekigan on Vocal Fold Wound Healing by Ozawa, Satomi, Mukudai, Shigeyuki, Kaneko, Mami, Kinoshita, Shota, Hashimoto, Keiko, Sugiyama, Yoichiro, Hashimoto, Subaru, Akaki, Junji, Hirano, Shigeru

“…The Japanese herbal medicine kyoseihatekigan (KHG) has been used to alleviate the symptoms of croaky voice and globus hystericus, and each of its components…”
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Effect of pharmacological inhibition of the pontine respiratory group on swallowing interneurons in the dorsal medulla oblongata by Takemura, Akiyo, Sugiyama, Yoichiro, Yamamoto, Ryota, Kinoshita, Shota, Kaneko, Mami, Fuse, Shinya, Hashimoto, Keiko, Mukudai, Shigeyuki, Umezaki, Toshiro, Dutschmann, Mathias, Hirano, Shigeru

“…[Display omitted] •Swallowing motor amplitudes were decreased after pontine inhibition.•The swallow frequency was increased after pontine inhibition.•The…”
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Intracellular Cl - Regulation of Ciliary Beating in Ciliated Human Nasal Epithelial Cells: Frequency and Distance of Ciliary Beating Observed by High-Speed Video Microscopy by Yasuda, Makoto, Inui, Taka-Aki, Hirano, Shigeru, Asano, Shinji, Okazaki, Tomonori, Inui, Toshio, Marunaka, Yoshinori, Nakahari, Takashi

“…Small inhaled particles, which are entrapped by the mucous layer that is maintained by mucous secretion via mucin exocytosis and fluid secretion, are removed…”
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Angiosarcoma arising from nasal cavity; A case report by Kimura, Alisa, Yasuda, Makoto, Okamoto, Shota, Tsujikawa, Takahiro, Hirano, Shigeru

“…AbstractAngiosarcoma is a rare malignant tumor, even rarer particularly in the head and neck. It is considered a very aggressive neoplasm with high rates of…”
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