Search Results - "HIRANO, Gen"

NUT carcinoma of the nasal cavity that responded to a chemotherapy regimen for Ewing's sarcoma family of tumors: a case report by Arimizu, Kohei, Hirano, Gen, Makiyama, Chinatsu, Matsuo, Mioko, Sasaguri, Takakazu, Makiyama, Akitaka

“…Nuclear protein in testis (NUT) carcinoma (NC) is a rare epithelial malignancy characterized by rearrangement of the NUT gene on chromosome 15. If NC is not…”
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Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer by Makiyama, Akitaka, Arimizu, Kohei, Hirano, Gen, Makiyama, Chinatsu, Matsushita, Yuzo, Shirakawa, Tsuyoshi, Ohmura, Hirofumi, Komoda, Masato, Uchino, Keita, Inadomi, Kyoko, Arita, Shuji, Ariyama, Hiroshi, Kusaba, Hitoshi, Shinohara, Yudai, Kuwayama, Miyuki, Kajitani, Tatsuhiro, Oda, Hisanobu, Esaki, Taito, Akashi, Koichi, Baba, Eishi

“…Background Patients with advanced gastric cancer (AGC) are often treated with irinotecan monotherapy as salvage-line therapy. However, the survival benefit of…”
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Y‐box binding protein‐1 is a novel molecular target for tumor vessels by Takahashi, Mayu, Shimajiri, Shohei, Izumi, Hiroto, Hirano, Gen, Kashiwagi, Eiji, Yasuniwa, Yoshihiro, Wu, Ying, Han, Bin, Akiyama, Masaki, Nishizawa, Shigeru, Sasaguri, Yasuyuki, Kohno, Kimitoshi

“…Y‐box binding protein‐1 (YB‐1) is a member of the cold shock protein family and functions in transcription and translation. Many reports indicate that YB‐1 is…”
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Circadian disruption accelerates tumor growth and angio/stromagenesis through a Wnt signaling pathway by Yasuniwa, Yoshihiro, Izumi, Hiroto, Wang, Ke-Yong, Shimajiri, Shohei, Sasaguri, Yasuyuki, Kawai, Kazuaki, Kasai, Hiroshi, Shimada, Takashi, Miyake, Koichi, Kashiwagi, Eiji, Hirano, Gen, Kidani, Akihiko, Akiyama, Masaki, Han, Bin, Wu, Ying, Ieiri, Ichiro, Higuchi, Shun, Kohno, Kimitoshi

“…Epidemiologic studies show a high incidence of cancer in shift workers, suggesting a possible relationship between circadian rhythms and tumorigenesis…”
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A double‐blind, randomized, multicenter phase 3 study of palonosetron vs granisetron combined with dexamethasone and fosaprepitant to prevent chemotherapy‐induced nausea and vomiting in patients with breast cancer receiving anthracycline and cyclophosphamide by Matsumoto, Koji, Takahashi, Masato, Sato, Kazuhiko, Osaki, Akihiko, Takano, Toshimi, Naito, Yoichi, Matsuura, Kazuo, Aogi, Kenjiro, Fujiwara, Kimiko, Tamura, Kenji, Baba, Motoi, Tokunaga, Shinya, Hirano, Gen, Imoto, Shigeru, Miyazaki, Chieko, Yanagihara, Kazuhiro, Imamura, Chiyo K., Chiba, Yasutaka, Saeki, Toshiaki

“…Purpose To investigate whether palonosetron is better than granisetron in preventing chemotherapy‐induced nausea and vomiting (CINV) in a three‐drug…”
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Enhanced expression of PCAF endows apoptosis resistance in cisplatin-resistant cells by Hirano, Gen, Izumi, Hiroto, Kidani, Akihiko, Yasuniwa, Yoshihiro, Han, Bin, Kusaba, Hitoshi, Akashi, Koichi, Kuwano, Michihiko, Kohno, Kimitoshi

“…Histone acetyltransferase (HAT) regulates transcription. We have previously shown that two HAT genes, Clock and Tip60, are overexpressed, and upregulate…”
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P2-096A retrospective study to compare TAS-102 with TAS-102+BV in advanced colorectal cancer refractory to standard therapy by Makiyama, Akitaka, Yamaga, Satoru, Hirano, Gen, Makiyama, Chinatsu, Muta, Tsuyoshi

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A retrospective study to compare TAS-102 with TAS-102+BV in advanced colorectal cancer refractory to standard therapy by Makiyama, Akitaka, Yamaga, Satoru, Hirano, Gen, Makiyama, Chinatsu, Muta, Tsuyoshi

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Salvage line CPT-11 after failure of fluoropyrimidine and paclitaxel-based chemotherapy in advanced gastric cancer by Makiyama, Chinatsu, Hirano, Gen, Makiyama, Akitaka, Muta, Tsuyoshi

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Successful treatment with “re-switching” of regorafenib and cetuximab for mCRC patient with liver metastases by Makiyama, Akitaka, Hirano, Gen, Makiyama, Chinatsu, Muta, Tsuyoshi

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Programmed Cell Death Protein 4 Down-regulates Y-Box Binding Protein-1 Expression via a Direct Interaction with Twist1 to Suppress Cancer Cell Growth by SHIOTA, Masaki, IZUMI, Hiroto, YASUNIWA, Yoshihiro, NAITO, Seiji, NISHIZAWA, Shigeru, SASAGURI, Yasuyuki, KOHNO, Kimitoshi, TANIMOTO, Akihide, TAKAHASHI, Mayu, MIYAMOTO, Naoya, KASHIWAGI, Eiji, KIDANI, Akihiko, HIRANO, Gen, MASUBUCHI, Daisuke, FUKUNAKA, Yasushi

“…Programmed cell death protein 4 (PDCD4) has recently been shown to be involved in both transcription and translation, and to regulate cell growth. However, the…”
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Efficacy and Safety Analysis of Oxaliplatin-based Chemotherapy for Advanced Gastric Cancer by Inadomi, Kyoko, Kusaba, Hitoshi, Matsushita, Yuzo, Tanaka, Risa, Mitsugi, Kenji, Arimizu, Kohei, Hirano, Gen, Makiyama, Akitaka, Ohmura, Hirofumi, Uchino, Keita, Hanamura, Fumiyasu, Shibata, Yoshihiro, Kuwayama, Miyuki, Esaki, Taito, Takayoshi, Kotoe, Arita, Shuji, Ariyama, Hiroshi, Akashi, Koichi, Baba, Eishi

“…Significant efficacy of oxaliplatin-based chemotherapy has been demonstrated for advanced gastric cancer (AGC). However, the appropriate dose of oxaliplatin,…”
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Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells by Uchino, Keita, Hirano, Gen, Hirahashi, Minako, Isobe, Taichi, Shirakawa, Tsuyoshi, Kusaba, Hitoshi, Baba, Eishi, Tsuneyoshi, Masazumi, Akashi, Koichi

“…There is emerging evidence that human solid tumor cells originate from cancer stem cells (CSCs). In cancer cell lines, tumor-initiating CSCs are mainly found…”
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Biomarker study for trastuzumab continuation beyond progression in a randomized phase II trial of weekly paclitaxel±trastuzumab in patients with HER2-positive advanced gastric or gastro-esophageal junction cancer refractory to trastuzumab combined with fluoropyrimidine and platinum (WJOG7112G) by Sukawa, Yasutaka, Makiyama, Akitaka, Esaki, Taito, Hirano, Gen, Komoda, Masato, Kashiwada, Tomomi, Kawada, Junji, Hosokawa, Ayumu, Tsuda, Takashi, Tsuji, Akihito, Moriwaki, Toshikazu, Tanioka, Hiroaki, Yonesaka, Kimio, Nishio, Kazuto, Nosho, Katsuhiko, Yamazaki, Kentaro, Hironaka, Shuichi, Boku, Narikazu, Hyodo, Ichinosuke, Muro, Kei

“…Abstract only…”
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Efficacy and Safety of TAS-102 in Clinical Practice of Salvage Chemotherapy for Metastatic Colorectal Cancer by Arita, Shuji, Shirakawa, Tsuyoshi, Matsushita, Yuzo, Shimokawa, Hozumi Kumagai, Hirano, Gen, Makiyama, Akitaka, Shibata, Yoshihiro, Tamura, Shingo, Esaki, Taito, Mitsugi, Kenji, Ariyama, Hiroshi, Kusaba, Hitoshi, Akashi, Koichi, Baba, Eishi

“…TAS-102 is an anti-metabolite which demonstrated activity against multidrug-resistant advanced colorectal cancer. Its major toxicities are hematological…”
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A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy by Kumagai, Hozumi, Kusaba, Hitoshi, Yamanaka, Takeharu, Nio, Kenta, Inadomi, Kyoko, Takayoshi, Kotoe, Ito, Mamoru, Tamura, Shingo, Makiyama, Akitaka, Makiyama, Chinatsu, Hirano, Gen, Shibata, Yoshihiro, Shirakawa, Tsuyoshi, Mitsugi, Kenji, Ariyama, Hiroshi, Esaki, Taito, Akashi, Koichi, Baba, Eishi

“…Combination therapy of fosaprepitant, dexamethasone (DEX) and a serotonin (5-HT3) receptor antagonist is a standard antiemetic prophylaxis for patients…”
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Significance of hypersensitivity reactions in the outpatient infusion unit: Retrospective study in JCHO Kyushu hospital by Tomoda, Kyoko, Muta, Tsuyoshi, Ono, Ayako, Makiyama, Chinatsu, Hirano, Gen, Makiyama, Akitaka, Aoki, Kenichi, Ogawa, Ryosuke, Umeda, Shuyo, Uchiyama, Akihiko

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Trifluridine-tipiracil for multidrug-resistant advanced colorectal cancer: A multicenter retrospective study by Arita, Shuji, Shirakawa, Tsuyoshi, Matsushita, Yuzo, Kumagai, Hozumi, Hirano, Gen, Makiyama, Akitaka, Shibata, Yoshihiro, Tamura, Shingo, Kusaba, Hitoshi, Baba, Eishi

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Reduced dose of salvage-line regorafenib monotherapy for metastatic colorectal cancer in Japan by Hirano, Gen, Makiyama, Akitaka, Makiyama, Chinatsu, Esaki, Taito, Oda, Hisanobu, Uchino, Keita, Komoda, Masato, Tanaka, Risa, Matsushita, Yuzo, Mitsugi, Kenji, Shibata, Yoshihiro, Kumagai, Hozumi, Arita, Shuji, Ariyama, Hiroshi, Kusaba, Hitoshi, Akashi, Koichi, Baba, Eishi

“…Salvage-line regorafenib monotherapy exhibited a marked survival benefit for metastatic colorectal cancer (mCRC). However, the toxicity of this regimen has…”
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Early tumor shrinkage indicates a favorable response to bevacizumab-based first-line chemotherapy for metastatic colorectal cancer by Ito, Mamoru, Kusaba, Hitoshi, Mukaide, Satomi, Kishimoto, Junji, Shimokawa, Hozumi, Tamura, Shingo, Makiyama, Akitaka, Hirano, Gen, Oda, Hisanobu, Shirakawa, Tsuyoshi, Komoda, Masato, Uchino, Keita, Tanaka, Risa, Mitsugi, Kenji, Esaki, Taito, Arita, Shuji, Ariyama, Hiroshi, Akashi, Koichi, Baba, Eishi

“…A close correlation between early tumor shrinkage (ETS) and overall survival (OS) has been shown in antiepidermal growth factor receptor antibody-based…”
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