Search Results - "HIRABAYASHI, Jun"

Lectin microarrays: concept, principle and applications by Hirabayashi, Jun, Yamada, Masao, Kuno, Atsushi, Tateno, Hiroaki

“…The lectin microarray is a novel platform for glycan analysis, having emerged only in recent years. Unlike other conventional methods, e.g., liquid…”
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Lectin engineering: the possible and the actual by Hirabayashi, Jun, Arai, Ryoichi

“…Lectins are a widespread group of sugar-binding proteins occurring in all types of organisms including animals, plants, bacteria, fungi and even viruses…”
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Concept, Strategy and Realization of Lectin-based Glycan Profiling by Hirabayashi, Jun

“…Lectins are a diverse group of carbohydrate-binding proteins. Each lectin has its own specificity profile. It is believed that lectins exist in all living…”
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An insight into pluripotency and cellular aging through glycan analysis by Jun, Hirabayashi

“…All kinds of cells from all kinds of organisms (i.e., animals, plants, fungi and bacteria) are covered by a dense layer of glycans. The origin of glycans or…”
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Visualization of Galectin-3 Oligomerization on the Surface of Neutrophils and Endothelial Cells Using Fluorescence Resonance Energy Transfer by Nieminen, Julie, Kuno, Atsushi, Hirabayashi, Jun, Sato, Sachiko

“…Galectin-3, a member of the galectin family of carbohydrate binding proteins, is widely expressed, particularly in cells involved in the immune response…”
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Lectin-based structural glycomics: glycoproteomics and glycan profiling by Hirabayashi, Jun

“…Structural glycomics (SG) plays a fundamental part of concurrent glycobiology aiming at comprehensive elucidation of glycan functions ( i.e. , functional…”
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DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis by Kaifu, Tomonori, Yabe, Rikio, Maruhashi, Takumi, Chung, Soo-Hyun, Tateno, Hiroaki, Fujikado, Noriyuki, Hirabayashi, Jun, Iwakura, Yoichiro

“…Dendritic cell immunoreceptor (DCIR) is a C-type lectin receptor with a carbohydrate recognition domain and an immunoreceptor tyrosine-based inhibitory motif…”
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Sugar-Binding Profiles of Chitin-Binding Lectins from the Hevein Family: A Comprehensive Study by Itakura, Yoko, Nakamura-Tsuruta, Sachiko, Kominami, Junko, Tateno, Hiroaki, Hirabayashi, Jun

“…Chitin-binding lectins form the hevein family in plants, which are defined by the presence of single or multiple structurally conserved GlcNAc…”
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Lectin engineering, a molecular evolutionary approach to expanding the lectin utilities by Hu, Dan, Tateno, Hiroaki, Hirabayashi, Jun

“…In the post genomic era, glycomics--the systematic study of all glycan structures of a given cell or organism--has emerged as an indispensable technology in…”
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Structural and quantitative evidence of α2–6-sialylated N-glycans as markers of the differentiation potential of human mesenchymal stem cells by Hasehira, Kayo, Hirabayashi, Jun, Tateno, Hiroaki

“…Human somatic stem cells such as mesenchymal stem cells (hMSCs) have the capacity to differentiate into mesenchymal tissue lineages and to alter immune…”
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C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia by Yamasaki, Sho, Matsumoto, Makoto, Takeuchi, Osamu, Matsuzawa, Tetsuhiro, Ishikawa, Eri, Sakuma, Machie, Tateno, Hiroaki, Uno, Jun, Hirabayashi, Jun, Mikami, Yuzuru, Takeda, Kiyoshi, Akira, Shizuo, Saito, Takashi

“…Mincle (also called as Clec4e and Clecsf9) is a C-type lectin receptor expressed in activated phagocytes. Recently, we have demonstrated that Mincle is an…”
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Lectin-based structural glycomics: A practical approach to complex glycans by Hirabayashi, Jun, Kuno, Atsushi, Tateno, Hiroaki

“…Glycans exist in nature in various forms of glycoconjugates, i.e., glycoproteins, glycolipids, and glycosaminoglycans, either in soluble or membrane‐bound…”
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Structural and Quantitative Evidence for Dynamic Glycome Shift on Production of Induced Pluripotent Stem Cells by Hasehira, Kayo, Tateno, Hiroaki, Onuma, Yasuko, Ito, Yuzuru, Asashima, Makoto, Hirabayashi, Jun

“…We recently reported that induced pluripotent stem cells (iPSCs) prepared from different human origins acquired similar glycan profiles to one another as well…”
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Glycome Diagnosis of Human Induced Pluripotent Stem Cells Using Lectin Microarray by Tateno, Hiroaki, Toyota, Masashi, Saito, Shigeru, Onuma, Yasuko, Ito, Yuzuru, Hiemori, Keiko, Fukumura, Mihoko, Matsushima, Asako, Nakanishi, Mio, Ohnuma, Kiyoshi, Akutsu, Hidenori, Umezawa, Akihiro, Horimoto, Katsuhisa, Hirabayashi, Jun, Asashima, Makoto

“…Induced pluripotent stem cells (iPSCs) can now be produced from various somatic cell (SC) lines by ectopic expression of the four transcription factors…”
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rBC2LCN, a new probe for live cell imaging of human pluripotent stem cells by Onuma, Yasuko, Tateno, Hiroaki, Hirabayashi, Jun, Ito, Yuzuru, Asashima, Makoto

“…► Live or fixed colonies of human ESC/iPSC are visualized by fluorescent dye-labeled rBC2LCN. ► rBC2LCN is highly sensitive to cell differentiation. ►…”
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A Novel Therapeutic Strategy for Pancreatic Cancer: Targeting Cell Surface Glycan Using rBC2LC-N Lectin-Drug Conjugate (LDC) by Shimomura, Osamu, Oda, Tatsuya, Tateno, Hiroaki, Ozawa, Yusuke, Kimura, Sota, Sakashita, Shingo, Noguchi, Masayuki, Hirabayashi, Jun, Asashima, Makoto, Ohkohchi, Nobuhiro

“…Various cancers, including pancreatic ductal adenocarcinoma (PDAC), remain intractable even with costly tumor-targeting antibody drugs. Because the outermost…”
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Engineering of recombinant Wisteria floribunda agglutinin specifically binding to GalNAcβ1,4GlcNAc (LacdiNAc) by Sato, Takashi, Tateno, Hiroaki, Kaji, Hiroyuki, Chiba, Yasunori, Kubota, Tomomi, Hirabayashi, Jun, Narimatsu, Hisashi

“…Wisteria floribunda agglutinin (WFA) is a useful probe for distinguishing glycan structural alterations in diseases such as intrahepatic bile duct carcinoma…”
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Mechanism of explosive eruption revealed by geophysical observations at the Sakurajima, Suwanosejima and Semeru volcanoes by Iguchi, Masato, Yakiwara, Hiroshi, Tameguri, Takeshi, Hendrasto, Muhamad, Hirabayashi, Jun-ichi

“…A common sequence of phenomena associated with volcanic explosions is extracted based on seismic and ground deformation observations at 3 active volcanoes in…”
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Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion‐exchange method by Seo, Naohiro, Nakamura, Junko, Kaneda, Tsuguhiro, Tateno, Hiroaki, Shimoda, Asako, Ichiki, Takanori, Furukawa, Koichi, Hirabayashi, Jun, Akiyoshi, Kazunari, Shiku, Hiroshi

“…The development of a new large‐scale purification protocol is required for research on the reliable bioactivity and drug discovery of extracellular vesicles…”
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Frontal affinity chromatography: sugar-protein interactions by Hirabayashi, Jun, Tateno, Hiroaki, Nakamura-Tsuruta, Sachiko

“…Frontal affinity chromatography using fluorescence detection (FAC-FD) is a versatile technique for the precise determination of dissociation constants (Kd)…”
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