Search Results - "HIPKENS, Susan B"

Informatic and Functional Approaches to Identifying a Regulatory Region for the Cardiac Sodium Channel by Atack, Thomas C, Myers Stroud, Dina, Watanabe, Hiroshi, Yang, Tao, Hall, Lynn, Hipkens, Susan B, Lowe, John S, Leake, Brenda, Magnuson, Mark A, Yang, Ping, Roden, Dan M

“…RATIONALE:Although multiple lines of evidence suggest that variable expression of the cardiac sodium channel gene SCN5A plays a role in susceptibility to…”
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A recombinase-mediated cassette exchange-derived cyan fluorescent protein reporter allele for Pdx1 by Potter, Leah A., Choi, Eunyoung, Hipkens, Susan B., Wright, Christopher V.E., Magnuson, Mark A.

“…Fluorescent protein (FP) reporter alleles are useful both for identifying and purifying specific cell populations in the mouse. Here, we report the generation…”
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Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming by Papizan, James B, Singer, Ruth A, Tschen, Shuen-Ing, Dhawan, Sangeeta, Friel, Jessica M, Hipkens, Susan B, Magnuson, Mark A, Bhushan, Anil, Sussel, Lori

“…Regulation of cell differentiation programs requires complex interactions between transcriptional and epigenetic networks. Elucidating the principal molecular…”
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Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3 by Osipovich, Anna B, Long, Qiaoming, Manduchi, Elisabetta, Gangula, Rama, Hipkens, Susan B, Schneider, Judsen, Okubo, Tadashi, Stoeckert, Jr, Christian J, Takada, Shinji, Magnuson, Mark A

“…Insulinoma associated 1 (Insm1) plays an important role in regulating the development of cells in the central and peripheral nervous systems, olfactory…”
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Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells by Bechard, Matthew E, Bankaitis, Eric D, Hipkens, Susan B, Ustione, Alessandro, Piston, David W, Yang, Yu-Ping, Magnuson, Mark A, Wright, Christopher V E

“…The current model for endocrine cell specification in the pancreas invokes high-level production of the transcription factor Neurogenin 3 (Neurog3) in Sox9(+)…”
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Striking In Vivo Phenotype of a Disease-Associated Human SCN5A Mutation Producing Minimal Changes in Vitro by WATANABE, Hiroshi, TAO YANG, KUPERSHMIDT, Sabina, CHOPRA, Nagesh, MAGNUSON, Mark A, TANABE, Naohito, KNOLLMANN, Björn C, GEORGE, Alfred L, RODEN, Dan M, MYERS STROUD, Dina, LOWE, John S, HARRIS, Louise, ATACK, Thomas C, WANG, Dao W, HIPKENS, Susan B, LEAKE, Brenda, HALL, Lynn

“…The D1275N SCN5A mutation has been associated with a range of unusual phenotypes, including conduction disease and dilated cardiomyopathy, as well as atrial…”
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Generation of Nkx2.2:lacZ mice using recombination-mediated cassette exchange technology by Arnes, Luis, Leclerc, Kevin, Friel, Jessica M., Hipkens, Susan B., Magnuson, Mark A., Sussel, Lori

“…Nkx2.2 encodes a homeodomain transcription factor required for the correct specification and/or differentiation of cells in the pancreas, intestine, and…”
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Age-related decline in striatal dopamine release and motoric function in Brown Norway/Fischer 344 hybrid rats by Yurek, David M, Hipkens, Susan B, Hebert, Meleik A, Gash, Don M, Gerhardt, Greg A

“…The Brown Norway/Fischer 344 F1 hybrid rats (F344BNF 1) is a newer rat model and is emerging as an important rodent model of aging. In the present study we…”
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Optimal Effectiveness of BDNF for Fetal Nigral Transplants Coincides with the Ontogenic Appearance of BDNF in the Striatum by Yurek, David M, Hipkens, Susan B, Wiegand, Stanley J, Altar, C. Anthony

“…Transplantation of fetal nigral dopamine neurons into the caudate and putamen of Parkinson's disease patients produces limited symptomatic relief. One approach…”
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An RMCE-derived cyan fluorescent protein reporter allele for Pdx1 by Potter, Leah A., Choi, Eunyoung, Hipkens, Susan B., Wright, Christopher V.E., Magnuson, Mark A.

“…Fluorescent protein (FP) reporter alleles are useful both for identifying and purifying specific cell populations in the mouse. Here, we report the generation…”
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Intranigral injections of SCH 23390 inhibit amphetamine-induced rotational behavior by Yurek, D M, Hipkens, S B

“…Rats were given unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway and permanent indwelling cannula were surgically implanted into the…”
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Intranigral injections of SCH 23390 inhibit SKF 82958-induced rotational behavior by Yurek, D M, Hipkens, S B

“…The selective D1 receptor antagonist, SCH 23390, was injected into the pars reticulata region of the lesioned substantia nigra at various concentrations (3.0,…”
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