Search Results - "HINTON, C"

transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium by Kröger, Carsten, Dillon, Shane C, Cameron, Andrew D. S, Papenfort, Kai, Sivasankaran, Sathesh K, Hokamp, Karsten, Chao, Yanjie, Sittka, Alexandra, Hébrard, Magali, Händler, Kristian, Colgan, Aoife, Leekitcharoenphon, Pimlapas, Langridge, Gemma C, Lohan, Amanda J, Loftus, Brendan, Lucchini, Sacha, Ussery, David W, Dorman, Charles J, Thomson, Nicholas R, Vogel, Jörg, Hinton, Jay C. D

“…More than 50 y of research have provided great insight into the physiology, metabolism, and molecular biology of Salmonella enterica serovar Typhimurium (S…”
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Understanding Human Neural Control of Short-term Gait Adaptation to the Split-belt Treadmill by Hinton, Dorelle C., Conradsson, David Moulaee, Paquette, Caroline

“…•We propose a model describing the roles of the human CNS during split-belt treadmill gait adaptation.•Initial adjustments to split-belts rely on…”
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Superfolder GFP reporters validate diverse new mRNA targets of the classic porin regulator, MicF RNA by Corcoran, Colin P., Podkaminski, Dimitri, Papenfort, Kai, Urban, Johannes H., Hinton, Jay C. D., Vogel, Jörg

“…Summary MicF is a textbook example of a small regulatory RNA (sRNA) that acts on a trans‐encoded target mRNA through imperfect base pairing. Discovery of MicF…”
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H-NS mediates the silencing of laterally acquired genes in bacteria by Lucchini, Sacha, Rowley, Gary, Goldberg, Martin D, Hurd, Douglas, Harrison, Marcus, Hinton, Jay C D

“…Histone-like nucleoid structuring protein (H-NS) is a modular protein that is associated with the bacterial nucleoid. We used chromatin immunoprecipitation to…”
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The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium by Colgan, Aoife M, Kröger, Carsten, Diard, Médéric, Hardt, Wolf-Dietrich, Puente, José L, Sivasankaran, Sathesh K, Hokamp, Karsten, Hinton, Jay C D

“…We know a great deal about the genes used by the model pathogen Salmonella enterica serovar Typhimurium to cause disease, but less about global gene…”
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RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium by Srikumar, Shabarinath, Kröger, Carsten, Hébrard, Magali, Colgan, Aoife, Owen, Siân V, Sivasankaran, Sathesh K, Cameron, Andrew D S, Hokamp, Karsten, Hinton, Jay C D

“…Salmonella enterica serovar Typhimurium is arguably the world's best-understood bacterial pathogen. However, crucial details about the genetic programs used by…”
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Lag Phase Is a Distinct Growth Phase That Prepares Bacteria for Exponential Growth and Involves Transient Metal Accumulation by Rolfe, Matthew D, Rice, Christopher J, Lucchini, Sacha, Pin, Carmen, Thompson, Arthur, Cameron, Andrew D. S, Alston, Mark, Stringer, Michael F, Betts, Roy P, Baranyi, József, Peck, Michael W, Hinton, Jay C. D

“…Lag phase represents the earliest and most poorly understood stage of the bacterial growth cycle. We developed a reproducible experimental system and conducted…”
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Pervasive post‐transcriptional control of genes involved in amino acid metabolism by the Hfq‐dependent GcvB small RNA by Sharma, Cynthia M., Papenfort, Kai, Pernitzsch, Sandy R., Mollenkopf, Hans‐Joachim, Hinton, Jay C. D., Vogel, Jörg

“…Summary GcvB is one of the most highly conserved Hfq‐associated small RNAs in Gram‐negative bacteria and was previously reported to repress several ABC…”
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Adjusting gait step-by-step: Brain activation during split-belt treadmill walking by Hinton, Dorelle C., Thiel, Alexander, Soucy, Jean-Paul, Bouyer, Laurent, Paquette, Caroline

“…When walking on a split-belt treadmill, where each leg is driven at a different speed, a temporary change is made to the typical steady-state walking pattern…”
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Alfvén Wave Propagation in the Io Plasma Torus by Hinton, P. C., Bagenal, F., Bonfond, B.

“…Io, the most volcanically active body in the solar system, fuels a plasma torus around Jupiter with dissociation products of SO2 at a rate of ~1,000 kg/s. We…”
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Decoding the stoichiometric composition and organisation of bacterial metabolosomes by Yang, Mengru, Simpson, Deborah M., Wenner, Nicolas, Brownridge, Philip, Harman, Victoria M., Hinton, Jay C. D., Beynon, Robert J., Liu, Lu-Ning

“…Some enteric bacteria including Salmonella have evolved the propanediol-utilising microcompartment (Pdu MCP), a specialised proteinaceous organelle that is…”
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Specific and pleiotropic patterns of mRNA regulation by ArcZ, a conserved, Hfq-dependent small RNA by Papenfort, Kai, Said, Nelly, Welsink, Tim, Lucchini, Sacha, Hinton, Jay C.D, Vogel, Jörg

“…The small RNA, ArcZ (previously RyhA/SraH), was discovered in several genome-wide screens in Escherichia coli and Salmonella. Its high degree of genomic…”
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Deep sequencing analysis of small noncoding RNA and mRNA targets of the global post-transcriptional regulator, Hfq by Sittka, Alexandra, Lucchini, Sacha, Papenfort, Kai, Sharma, Cynthia M, Rolle, Katarzyna, Binnewies, Tim T, Hinton, Jay C D, Vogel, Jörg

“…Recent advances in high-throughput pyrosequencing (HTPS) technology now allow a thorough analysis of RNA bound to cellular proteins, and, therefore, of…”
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Succinate utilisation by Salmonella is inhibited by multiple regulatory systems by Wenner, Nicolas, Zhu, Xiaojun, Rowe, Will P M, Händler, Kristian, Hinton, Jay C D

“…Succinate is a potent immune signalling molecule that is present in the mammalian gut and within macrophages. Both of these infection niches are colonised by…”
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ancestral SgrS RNA discriminates horizontally acquired Salmonella mRNAs through a single G-U wobble pair by Papenfort, Kai, Podkaminski, Dimitri, Hinton, Jay C. D, Vogel, Jörg

“…SgrS RNA is a model for the large class of Hfq-associated small RNAs that act to posttranscriptionally regulate bacterial mRNAs. The function of SgrS is…”
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Biogenesis of a bacterial metabolosome for propanediol utilization by Yang, Mengru, Wenner, Nicolas, Dykes, Gregory F., Li, Yan, Zhu, Xiaojun, Sun, Yaqi, Huang, Fang, Hinton, Jay C. D., Liu, Lu-Ning

“…Bacterial metabolosomes are a family of protein organelles in bacteria. Elucidating how thousands of proteins self-assemble to form functional metabolosomes is…”
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Intracellular niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of Salmonella enterica by Powers, TuShun R, Haeberle, Amanda L, Predeus, Alexander V, Hammarlöf, Disa L, Cundiff, Jennifer A, Saldaña-Ahuactzi, Zeus, Hokamp, Karsten, Hinton, Jay C D, Knodler, Leigh A

“…Salmonella enterica serovar Typhimurium (S. Typhimurium) is a zoonotic pathogen that causes diarrheal disease in humans and animals. During salmonellosis, S…”
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Butyrate Specifically Down-Regulates Salmonella Pathogenicity Island 1 Gene Expression by Gantois, I, Ducatelle, R, Pasmans, F, Haesebrouck, F, Hautefort, I, Thompson, A, Hinton, J. C, Van Immerseel, F

“…Invasion of intestinal epithelial cells by Salmonella enterica is decreased after exposure to butyric acid. To understand the molecular mechanisms of this…”
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An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes by Perez-Sepulveda, Blanca M, Heavens, Darren, Pulford, Caisey V, Predeus, Alexander V, Low, Ross, Webster, Hermione, Dykes, Gregory F, Schudoma, Christian, Rowe, Will, Lipscombe, James, Watkins, Chris, Kumwenda, Benjamin, Shearer, Neil, Costigan, Karl, Baker, Kate S, Feasey, Nicholas A, Hinton, Jay C D, Hall, Neil

“…We have developed an efficient and inexpensive pipeline for streamlining large-scale collection and genome sequencing of bacterial isolates. Evaluation of this…”
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Transcriptomic Analysis of Escherichia coli O157:H7 and K-12 Cultures Exposed to Inorganic and Organic Acids in Stationary Phase Reveals Acidulant- and Strain-Specific Acid Tolerance Responses by King, Thea, Lucchini, Sacha, Hinton, Jay C.D, Gobius, Kari

“…The food-borne pathogen Escherichia coli O157:H7 is commonly exposed to organic acid in processed and preserved foods, allowing adaptation and the development…”
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