Search Results - "HINSHELWOOD, M. M"

Mammalian aromatases by Conley, A, Hinshelwood, M

“…Aromatase is the enzyme complex that catalyses the synthesis of oestrogens from androgens, and therefore it has unique potential to influence the physiological…”
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Mechanisms in tissue-specific regulation of estrogen biosynthesis in humans by Kamat, Amrita, Hinshelwood, Margaret M, Murry, Barbara A, Mendelson, Carole R

“…In humans, aromatase P450, which catalyses conversion of C 19-steroids to estrogens, is expressed in several tissues, including gonads, brain, adipose tissue,…”
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Expression of LRH-1 and SF-1 in the mouse ovary: localization in different cell types correlates with differing function by Hinshelwood, Margaret M., Repa, Joyce J., Shelton, John M., Richardson, James A., Mangelsdorf, David J., Mendelson, Carole R.

“…Steroid biosynthesis in ovary is enhanced by the orphan nuclear receptor, steroidogenic factor-1 (SF-1); however, we reported that liver receptor homolog-1…”
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Transcriptional regulation of aromatase in placenta and ovary by Mendelson, Carole R., Jiang, Bing, Shelton, John M., Richardson, James A., Hinshelwood, Margaret M.

“…Our goal is to define the cellular and molecular mechanisms for tissue- and cell-specific, developmental and hormonal regulation of the human CYP19 (aromatase…”
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Functional aromatase expression in porcine adrenal gland and testis by Conley, A.J. (University of California at Davis, Davis, CA.), Corbin, C.J, Hinshelwood, M.M, Liu, Z, Simpson, E.R, Ford, J.J, Harada, N

“…The expression of aromatase cytochrome P450 (P450arom) in the adrenal glands, testes, and placentas of fetal and newborn pigs was investigated. Western…”
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Expression of the CYP19 (aromatase) gene: an unusual case of alternative promoter usage by Simpson, Evan R., Michael, M. Dodson, Agarwal, Veena R., Hinshelwood, Margaret M., Bulun, Serdar E., Zhao, Ying

“…Family 19 of the P450 super family is responsible for the conversion of C19 androgenic steroids to the corresponding estrogens, a reaction known as…”
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Temporal and spatial expression of liver receptor homologue‐1 (LRH‐1) during embryogenesis suggests a potential role in gonadal development by Hinshelwood, Margaret M., Shelton, John M., Richardson, James A., Mendelson, Carole R.

“…Liver receptor homologue‐1 (LRH‐1), an orphan member of the nuclear receptor family highly expressed in adult mouse ovary, is closely related to steroidogenic…”
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Demonstration of tissue-specific promoters in nonprimate species that express aromatase P450 in placentae by Hinshelwood, M.M. (University of Texas Southwestern Medical Center, Dallas, TX.), Liu, Z, Conley, A.J, Simpson, E.R

“…Conversion of androgens to estrogens is catalyzed by aromatase P450 (P450arom; the product of the CYP19 gene). Regulation of tissue-specific expression of…”
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Isolation and characterization of a complementary deoxyribonucleic acid insert encoding bovine aromatase cytochrome P450 by Hinshelwood, M M, Corbin, C J, Tsang, P C, Simpson, E R

“…Aromatase, an enzyme complex comprised of aromatase cytochrome P450 (P450arom; the product of the CYP19 gene) and the flavoprotein NADPH-cytochrome P450…”
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Endocrine disorders associated with inappropriately high aromatase expression by Bulun, Serdar E., Noble, Luis S., Takayama, Kazuto, Michael, M.Dodson, Agarwal, Veena, Fisher, Carolyn, Zhao, Ying, Hinshelwood, Margaret M., Ito, Yuji, Simpson, Evan R.

“…Aromatase P450 (P450 arom) is responsible for conversion of C 19 steroids to estrogens in a number of human tissues, such as the placenta, gonads, adipose…”
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The 5'-flanking region of the ovarian promoter of the bovine CYP19 gene contains a deletion in a cyclic adenosine 3',5'-monophosphate-like responsive sequence by Hinshelwood, M M, Michael, M D, Simpson, E R

“…Conversion of C19 steroids to estrogens is catalyzed by aromatase P450 (P450arom; the product of the CYP19 gene). In the ovary, P450arom is expressed in…”
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Case report: whole exome sequencing of primary cardiac angiosarcoma highlights potential for targeted therapies by Zhrebker, Leah, Cherni, Irene, Gross, Lara M, Hinshelwood, Margaret M, Reese, Merrick, Aldrich, Jessica, Guileyardo, Joseph M, Roberts, William C, Craig, David, Von Hoff, Daniel D, Mennel, Robert G, Carpten, John D

“…Primary cardiac angiosarcomas are rare, but they are the most aggressive type of primary cardiac neoplasms. When patients do present, it is with advanced…”
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A 278 bp Region Just Upstream of the Human CYP19 (Aromatase) Gene Mediates Ovary-Specific Expression in Transgenic Mice by Hinshelwood, Margaret M, Smith, Margaret E, Murry, Barbara A, Mendelson, Carole R

“…ABSTRACT In humans, the CYP19 gene, which encodes aromatase P450, is expressed in a number of tissues including gonads, adipose, bone, and placenta. The…”
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Tissue-specific expression of the human CYP19 (aromatase) gene in ovary and adipose tissue of transgenic mice by Hinshelwood, Margaret M, Mendelson, Carole R

“…In humans, the CYP19 (aromatase P450) gene is expressed in a number of tissues, including gonads, placenta, adipose tissue, skin and brain. The 5′-untranslated…”
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Aromatase expression in health and disease by Simpson, E R, Zhao, Y, Agarwal, V R, Michael, M D, Bulun, S E, Hinshelwood, M M, Graham-Lorence, S, Sun, T, Fisher, C R, Qin, K, Mendelson, C R

“…Family 19 of the P450 superfamily is responsible for the conversion of C19 androgenic steroids to the corresponding estrogens, a reaction known as…”
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A Putative Binding Site for Sp1 Is Involved in Transcriptional Regulation of CYP17 Gene Expression in Bovine Ovary by Borroni, Raffaella, Liu, Zheng, Simpson, Evan R., Hinshelwood, Margaret M.

“…Abstract In the bovine ovary, thecal cells are the only cell type capable of expressing the CYP17 gene in response to LH. With the onset of ovulation and…”
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Prostaglandin E2 stimulates aromatase expression in endometriosis-derived stromal cells by NOBLE, L. S, TAKAYAMA, K, ZEITOUN, K. M, PUTMAN, J. M, JOHNS, D. A, HINSHELWOOD, M. M, AGARWAL, V. R, ZHAO, Y, CARR, B. R, BULUN, S. E

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The farnesoid X receptor regulates transcription of 3β-hydroxysteroid dehydrogenase type 2 in human adrenal cells by Xing, Yewei, Saner-Amigh, Karla, Nakamura, Yasuhiro, Hinshelwood, Margaret M., Carr, Bruce R., Mason, J. Ian, Rainey, William E.

“…Recent studies have shown that the adrenal cortex expresses high levels of farnesoid X receptor (FXR), but its function remains unknown. Herein, using…”
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Estrogen Related Receptor-α Enhances Surfactant Protein-A Gene Expression in Fetal Lung Type II Cells by Liu, Dongyuan, Hinshelwood, Margaret M, Giguère, Vincent, Mendelson, Carole R

“…Surfactant protein-A (SP-A) gene expression is developmentally regulated in fetal lung type II cells in concert with surfactant glycerophospholipid synthesis…”
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Influence of suckling and side of corpus luteum or pregnancy on folliculogenesis in postpartum cows by Bellin, M.E, Hinsehlwood, M.M, Hauser, E.R, Ax, R.L

“…This study was designed to evaluate follicular development of 30 postpartum beef cows: 15 were suckled, and calves were removed from the other 15 within 24 h…”
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