Search Results - "HINOJOSA, Joaquin"

Succinate receptor mediates intestinal inflammation and fibrosis by Macias-Ceja, Dulce C., Ortiz-Masiá, Dolores, Salvador, Pedro, Gisbert-Ferrándiz, Laura, Hernández, Carlos, Hausmann, Martin, Rogler, Gerhard, Esplugues, Juan V., Hinojosa, Joaquín, Alós, Rafael, Navarro, Francisco, Cosin-Roger, Jesus, Calatayud, Sara, Barrachina, María D.

“…Succinate, an intermediate of the tricarboxylic acid cycle, is accumulated in inflamed areas and its signaling through succinate receptor (SUCNR1) regulates…”
Get full text

Old-age inflammatory bowel disease onset：A different problem by del Val, Joaquin Hinojosa

“…Inflammatory bowel disease （IBD） in patients aged 60 accounts for 10%-15% of cases of the disease. Diganostic methods are the same as for other age groups…”
Get full text

Safety of thiopurine therapy in inflammatory bowel disease: long-term follow-up study of 3931 patients by Chaparro, María, Ordás, Ingrid, Cabré, Eduard, Garcia-Sanchez, Valle, Bastida, Guillermo, Peñalva, Mireia, Gomollón, Fernando, García-Planella, Esther, Merino, Olga, Gutiérrez, Ana, Esteve, Maria, Márquez, Lucia, Garcia-Sepulcre, Maria, Hinojosa, Joaquín, Vera, Isabel, Muñoz, Fernando, Mendoza, Juan L, Cabriada, Jose L, Montoro, Miguel A, Barreiro-de Acosta, Manuel, Ceña, G, Saro, Cristina, Aldeguer, Xavier, Barrio, Jesús, Maté, José, Gisbert, Javier P

“…To evaluate the safety of thiopurines in patients with inflammatory bowel disease. To identify predictive factors associated with the development of…”
Get full text

Relationship between Serum Adalimumab Levels and Clinical Outcome in the Treatment of Inflammatory Bowel Disease by Hinojosa, Joaquín, Muñoz, Fernando, Martínez-Romero, Gregorio Juan

“…Adalimumab (ADA) is an anti-tumor necrosis factor agent that has been shown to be effective in inducing and maintaining remission in adult patients with…”
Get more information

M2 macrophages activate WNT signaling pathway in epithelial cells: relevance in ulcerative colitis by Cosín-Roger, Jesús, Ortiz-Masiá, Dolores, Calatayud, Sara, Hernández, Carlos, Alvarez, Angeles, Hinojosa, Joaquin, Esplugues, Juan V, Barrachina, Maria D

“…Macrophages, which exhibit great plasticity, are important components of the inflamed tissue and constitute an essential element of regenerative responses…”
Get full text

ApaI Polymorphism in the Vitamin D Receptor Gene Decreases the Risk of Perianal Fistulas in Crohn's Disease by Gisbert-Ferrándiz, Laura, Llau, Jorge, Ortiz-Masia, Dolores, Cosín-Roger, Jesús, Macias-Ceja, Dulce Carolina, Hinojosa, Joaquín, Calatayud, Sara, Barrachina, Maria Dolores

“…Vitamin D, through the activation of its receptor (VDR), plays an immunomodulatory role in the gastrointestinal tract. Single-nucleotide polymorphisms (SNPs)…”
Get full text

Timing of surgery in Crohn's disease: a key issue in the management by Alós, Rafael, Hinojosa, Joaquín

“…The timing of the decision for operation in Crohn's disease is based on an evaluation of the several factors such as the failure of medical treatment,…”
Get full text

Clinical settings with tofacitinib in ulcerative colitis by Taxonera, Carlos, Carpio López, Daniel, Cabez Manas, Ana, Hinojosa Del Val, Joaquin Ernesto

“…There are aspects of Janus kinase (JAK) inhibitors, specifically tofacitinib, that distinguish them from other drugs used in the treatment of ulcerative…”
Get full text

Induction of CD36 and thrombospondin-1 in macrophages by hypoxia-inducible factor 1 and its relevance in the inflammatory process by Ortiz-Masià, Dolores, Díez, Irene, Calatayud, Sara, Hernández, Carlos, Cosín-Roger, Jesús, Hinojosa, Joaquín, Esplugues, Juan V, Barrachina, María D

“…Inflammation is part of a complex biological response of vascular tissue to pathogens or damaged cells. First inflammatory cells attempt to remove the…”
Get full text

Diminished Vitamin D Receptor Protein Levels in Crohn's Disease Fibroblasts: Effects of Vitamin D by Gisbert-Ferrándiz, Laura, Cosín-Roger, Jesús, Hernández, Carlos, Macias-Ceja, Dulce C, Ortiz-Masiá, Dolores, Salvador, Pedro, Esplugues, Juan V, Hinojosa, Joaquín, Navarro, Francisco, Calatayud, Sara, Barrachina, María D

“…Vitamin D (VD) deficiency has been associated to Crohn's disease (CD) pathogenesis, and the exogenous administration of VD improves the course of the disease,…”
Get full text

Fecal Calprotectin Pretreatment and Induction Infliximab Levels for Prediction of Primary Nonresponse to Infliximab Therapy in Crohn's Disease by Beltrán, Belén, Iborra, Marisa, Sáez-González, Esteban, Marqués-Miñana, Maria R, Moret, Inés, Cerrillo, Elena, Tortosa, Luis, Bastida, Guillermo, Hinojosa, Joaquín, Poveda-Andrés, Jose Luis, Nos, Pilar

“…The association between infliximab (IFX) and fecal calprotectin (FC) levels on one hand, and the clinical and endoscopic response of patients with inflammatory…”
Get more information

Adalimumab vs Azathioprine in the Prevention of Postoperative Crohn's Disease Recurrence. A GETECCU Randomised Trial by López-Sanromán, Antonio, Vera-Mendoza, Isabel, Domènech, Eugeni, Taxonera, Carlos, Vega Ruiz, Vicente, Marín-Jiménez, Ignacio, Guardiola, Jordi, Castro, Luisa, Esteve, María, Iglesias, Eva, Ceballos, Daniel, Martínez-Montiel, Pilar, Gisbert, Javier P, Mínguez, Miguel, Echarri, Ana, Calvet, Xavier, Barrio, Jesús, Hinojosa, Joaquín, Martín-Arranz, María Dolores, Márquez-Mosquera, Lucía, Bermejo, Fernando, Rimola, Jordi, Pons, Vicente, Nos, Pilar

“…Postoperative recurrence of Crohn's disease [POR-CD] is almost certain if no prophylaxis is administered. Evidence for optimal treatment is lacking. Our aim…”
Get full text

A Single Nucleotide Polymorphism in the Vitamin D Receptor Gene Is Associated With Decreased Levels of the Protein and a Penetrating Pattern in Crohn's Disease by Gisbert-Ferrándiz, Laura, Salvador, Pedro, Ortiz-Masiá, Dolores, Macías-Ceja, Dulce Carolina, Orden, Samuel, Esplugues, Juan Vicente, Calatayud, Sara, Hinojosa, Joaquín, Barrachina, Maria Dolores, Hernández, Carlos

“…Abstract Background Vitamin D signaling modulates inflammation through the vitamin D receptor (VDR). The synonymous single nucleotide polymorphism (SNP)…”
Get full text

Recommendations of the Crohn's Disease and Ulcerative Colitis Spanish Working Group (GETECCU) for the treatment of perianal fistulas of Crohn's disease by Boscá, Marta M, Alós, Rafael, Maroto, Nuria, Gisbert, Javier P, Beltrán, Belén, Chaparro, María, Nos, Pilar, Mínguez, Miguel, Hinojosa, Joaquín

“…Recommendations are advice that is given and considered to be beneficial; however, they are still suggestions and are therefore open to different…”
Get more information

GADECCU 2022 Guideline for the treatment of Ulcerative Colitis. Adaptation and updating of the GETECCU 2020 Guideline by Fuxman, Claudia, Sicilia, Beatriz, Linares, María Eugenia, García-López, Santiago, González Sueyro, Ramiro, González-Lamac, Yago, Zabana, Yamile, Hinojosa, Joaquín, Barreiro-de Acosta, Manuel, Balderramo, Domingo, Balfour, Deborah, Bellicoso, Maricel, Daffra, Pamela, Morelli, Daniela, Orsi, Marina, Rausch, Astrid, Ruffinengo, Orlando, Toro, Martín, Sambuelli, Alicia, Novillo, Abel, Gomollón, Fernando, De Paula, Juan Andrés

“…Ulcerative colitis (UC) is a chronic inflammatory disease that compromises the colon, affecting the quality of life of individuals of any age. In practice,…”
Get more information

Validation of a population pharmacokinetic model of adalimumab in a cohort of patients with inflammatory bowel disease by Martínez-Romero, Gregorio J, Alvariño, Ana, Hinojosa, Esther, Mora, Maria, Oltra, Lorena, Maroto, Nuria, Ferrer, Isabel, Hinojosa, María Dolores, Hinojosa, Joaquin Ernesto

“…therapeutic monitoring of anti-TNF drugs and anti-drug antibody levels are useful for clinical decision-making, via the rationalization and optimization of the…”
Get full text

Usefulness of monitoring antitumor necrosis factor serum levels during the induction phase in patients with Crohn’s disease by Chaparro, María, Guerra, Iván, Iborra, Marisa, Cabriada, José Luis, Bujanda, Luis, Taxonera, Carlos, García-Sánchez, Valle, Marín-Jiménez, Ignacio, Barreiro-de Acosta, Manuel, Vera, Isabel, Martín-Arranz, María Dolores, Hernández-Breijo, Borja, Mesonero, Francisco, Sempere, Laura, Gomollón, Fernando, Hinojosa, Joaquín, Bermejo, Fernando, Beltrán, Belén, Rodríguez Pescador, Ainhoa, Banales, Jesús María, Olivares, David, Aguilar-Melero, Patricia, Menchén, Luis, Ferreiro-Iglesias, Rocío, Blazquez Gomez, Isabel, Benítez García, Belén, Guijarro, Luis González, Marin, Alicia, Bernardo, David, Gisbert, Javier P.

“…The aims of this study were (a) to know the kinetics of antitumor necrosis factor (TNF) drug serum levels during the induction phase in patients with Crohn's…”
Get full text

Joint position statement by “Sociedad Española de Patología Digestiva” (Spanish Society of Gastroenterology) and “Sociedad Española de Farmacología” (Spanish Society of Pharmacology) on biosimilar therapy for inflammatory bowel disease by Argüelles-Arias, Federico, Barreiro-de-Acosta, Manuel, Carballo, Fernando, Hinojosa, Joaquín, Tejerina, Teresa

“…Biological drugs or biopharmaceutical products, manufactured with or from living organisms using biotechnology, have represented a therapeutic revolution for…”
Get full text

Observational study on the efficacy of adalimumab for the treatment of ulcerative colitis and predictors of outcome by García-Bosch, Orlando, Gisbert, Javier P., Cañas-Ventura, Àlex, Merino, Olga, Cabriada, José L., García-Sánchez, Valle, Gutiérrez, Ana, Nos, Pilar, Peñalva, Mireia, Hinojosa, Joaquin, García-Planella, Esther, Muñoz, Fernando, Calvet, Xavier, Panés, Julián

“…Information on efficacy and predictors of response to adalimumab in ulcerative colitis (UC) clinical practice is limited. Assessment of response to adalimumab…”
Get full text

Information resources used by patients with inflammatory bowel disease: Satisfaction, expectations and information gaps by Catalán-Serra, Ignacio, Huguet-Malavés, Jose María, Mínguez, Miguel, Torrella, Emilio, Paredes, Jose María, Vázquez, Narciso, Ramírez, Jose Joaquín, Calvo, Félix, Nos, Pilar, Gutiérrez, Ana, Palau, Antonio, Cortés, Javier, Ramón-Monllor, Pilar, Hinojosa, Joaquín

“…Information received by IBD patients about their disease is of particular importance. The objective of the study was to determine the information resources…”
Get more information