Search Results - "HINKS, L. J."

The use of long PCR to confirm three common alleles at the CYP2A6 locus and the relationship between genotype and smoking habit by GU, D. F., HINKS, L. J., MORTON, N. E., DAY, I. N. M.

“…Long PCR followed by nested PCR has previously been used to determine CYP2A6 160H alleles, but the method proved unreliable. We have optimized this approach in…”
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A rapid method for haemophilia B mutation detection using conformation sensitive gel electrophoresis by Hinks, J. L., Winship, P. R., Makris, M., Preston, F. E., Peake, I. R., Goodeve, A. C.

“…Conformation sensitive gel electrophoresis (CSGE) was confirmed as an effective procedure for screening the factor IX (FIX) gene by detecting 10/10 previously…”
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A study of mitochondrial DNA mutations in peripheral lymphocytes in an aging cohort by Zhang, B, Ye, S, Sayer, A A, Hammans, S R, Adio, S, Hinks, L J, Smythe, P J, Groot, D, Cooper, C, Day, I N M

“…Somatic mutation in the mitochondrial genome occurs much more rapidly than in the nuclear genome and is a feature, possibly contributory, of the aging of cells…”
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The structure of the human gene encoding protein gene product 9.5 (PGP9.5), a neuron-specific ubiquitin C-terminal hydrolase by Day, I N, Hinks, L J, Thompson, R J

“…Database search using a bovine thymus ubiquitin C-terminal hydrolase sequence indicated 54% sequence identity with the abundant human neuron-specific protein…”
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Reduced selenium status of patients with asthma by Stone, J, Hinks, L J, Beasley, R, Holgate, S T, Clayton, B A

“…1. Selenium is an essential component of glutathione peroxidase (GSH-Px, EC 1.11.1.9), an enzyme which helps protects cells against damage caused by free…”
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Maternal zinc and selenium status in pregnancies with a neural tube defect or elevated plasma alpha-fetoprotein by Hinks, L J, Ogilvy-Stuart, A, Hambidge, K M, Walker, V

“…Zinc and selenium status was assessed in 30 non-pregnant women, 69 women during normal pregnancy, six with a fetus with a neural tube defect (NTD) and 16 who…”
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Reduced concentrations of selenium in mild Crohn's disease by Hinks, L J, Inwards, K D, Lloyd, B, Clayton, B

“…The concentrations of selenium, zinc, and copper were determined in whole blood, plasma, and leucocytes in 20 patients with relatively mild Crohn's disease,…”
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Metabolic balance studies for zinc and copper in housebound elderly people and the relationship between zinc balance and leukocyte zinc concentrations by Bunker, V W, Hinks, L J, Stansfield, M F, Lawson, M S, Clayton, B E

“…Five-day metabolic balance studies for zinc and copper were carried out in 20 housebound elderly people with stable chronic diseases. Subjects were age…”
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Trace element status in eczema and psoriasis by Hinks, L J, Young, S, Clayton, B

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Structure and chromosomal localization of the human 2',3'-cyclic nucleotide 3'-phosphodiesterase gene by Douglas, A J, Fox, M F, Abbott, C M, Hinks, L J, Sharpe, G, Povey, S, Thompson, R J

“…Human brain cDNA clones for the myelin associated enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) have been isolated and sequenced. The only 5'…”
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Assessment of zinc and copper status of healthy elderly people using metabolic balance studies and measurement of leucocyte concentrations by Bunker, V W, Hinks, L J, Lawson, M S, Clayton, B E

“…Metabolic balance studies for zinc and copper were carried out in 24 apparently healthy elderly people aged 69.7 to 85.5 yrs, living in their own homes and…”
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Manual 768 or 384 well microplate gel ‘dry’ electrophoresis for PCR checking and SNP genotyping by Gaunt, Tom R., Hinks, Lesley J., Rassoulian, Hamid, Day, Ian N. M.

“…Electrophoresis continues to be a mainstay in molecular genetic laboratories for checking, sizing and separating both PCR products, nucleic acids derived from…”
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Zinc absorption in haemodialysis patients by Foote, J W, Hinks, L J

“…The gastrointestinal absorption of zinc by haemodialysis patients has been investigated. Subnormal plasma zinc responses were observed in nine haemodialysis…”
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The gene for human neurone specific ubiquitin C-terminal hydrolase (UCHL1, PGP9.5) maps to chromosome 4p14 by Edwards, Y H, Fox, M F, Povey, S, Hinks, L J, Thompson, R J, Day, I N

“…Ubiquitin carboxy terminal hydrolase 1, UCHL1, is a neurone-specific protein involved in the ubiquitin-mediated proteolytic pathway. The gene for human UCHL1…”
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Determination of zinc and copper in isolated leucocytes by Hinks, L J, Colmsee, M, Delves, H T

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Case 4: assessment. An adolescent aged 14 has cystic fibrosis by Roberts, T, Schwarz, M J, Kerr-Liddell, R, Hinks, J L, Super, M

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Body Content Of Selenium In Coeliac Disease by Hinks, Lesley J., Inwards, Karen D., Lloyd, Barbara, Clayton, Barbara E.

“…Concentrations of selenium in whole blood, plasma, and leucocytes were determined in 16 patients with coeliac disease confirmed by biopsy and 32 controls. All…”
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Comparison of three methods for single nucleotide polymorphism typing for DNA bank studies: Sequence-specific oligonucleotide probe hybridisation, TaqMan liquid phase hybridisation, and microplate array diagonal gel electrophoresis (MADGE) by Holloway, John W., Beghé, Bianca, Turner, Steve, Hinks, Lesley J., Day, Ian N.M., Howell, W. Martin

“…In the near future the number of SNPs identified and mapped will increase and the need for high throughput SNP typing will be paramount for comprehensive…”
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Zinc and genital infections by Cornell, M S, Hinks, L J, Singha, H S, Walker, V, Willmott, F E

“…The zinc status of 19 patients with chronic or recurrent genital infections and 18 patients with non-recurrent genital infections was assessed by measuring…”
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Single strand conformation analysis of two genes contained within the first intron of the neurofibromatosis type I gene in patients with multiple sclerosis by Hinks, L J, Price, S E, Mason, C R, Thompson, R J

“…Single strand conformation analysis has become the most widely used technique to screen large numbers of DNA samples for unknown mutations which may contribute…”
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