Search Results - "HINGLEY, Susan T"
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Chlamydia pneumoniae : An Etiologic Agent for Late-Onset Dementia
Published in Frontiers in aging neuroscience (09-10-2018)“…The disease known as late-onset Alzheimer's disease is a neurodegenerative condition recognized as the single most commonform of senile dementia. The condition…”
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Endosomal Proteolysis by Cathepsins Is Necessary for Murine Coronavirus Mouse Hepatitis Virus Type 2 Spike-Mediated Entry
Published in Journal of Virology (01-06-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease
Published in BMC neuroscience (20-02-2019)“…Epidemiologic studies strongly suggest that the pathophysiology of late-onset Alzheimer disease (AD) versus early-onset AD has environmental rather than…”
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Experimental Optic Neuritis Induced by a Demyelinating Strain of Mouse Hepatitis Virus
Published in Journal of Virology (01-09-2008)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Gliopathy of Demyelinating and Non-Demyelinating Strains of Mouse Hepatitis Virus
Published in Frontiers in cellular neuroscience (22-12-2015)“…Demyelination in the central nervous system induced by neurovirulent strains of Mouse Hepatitis Virus (MHV) is mediated by the viral spike glycoprotein, but it…”
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Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of [beta]-amyloid found in Alzheimer disease
Published in BMC neuroscience (20-02-2019)“…Background Epidemiologic studies strongly suggest that the pathophysiology of late-onset Alzheimer disease (AD) versus early-onset AD has environmental rather…”
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Chlamydia pneumoniae infection of monocytes in vitro stimulates innate and adaptive immune responses relevant to those in Alzheimer's disease
Published in Journal of neuroinflammation (24-12-2014)“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which infection with Chlamydia pneumoniae (Cpn) has been associated. Cpn is an obligate…”
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Murine Coronavirus Evolution In Vivo: Functional Compensation of a Detrimental Amino Acid Substitution in the Receptor Binding Domain of the Spike Glycoprotein
Published in Journal of Virology (01-06-2005)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mechanisms of Primary Axonal Damage in a Viral Model of Multiple Sclerosis
Published in The Journal of neuroscience (19-08-2009)“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Recent studies have demonstrated that significant axonal injury also occurs in MS…”
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Sequence analysis of the S gene of recombinant MHV-2/A59 coronaviruses reveals three candidate mutations associated with demyelination and hepatitis
Published in Journal of neurovirology (01-10-2001)“…Coronaviruses, mouse hepatitis virus (MHV) strains, exhibit various degrees of neurotropism and hepatotropism following intracerebral (IC) infection of…”
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Murine Coronavirus Spike Protein Determines the Ability of the Virus To Replicate in the Liver and Cause Hepatitis
Published in Journal of Virology (01-03-2001)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Targeted Recombination within the Spike Gene of Murine Coronavirus Mouse Hepatitis Virus-A59: Q159 Is a Determinant of Hepatotropism
Published in Journal of Virology (01-12-1998)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mouse Hepatitis Virus Type-2 Infection in Mice: An Experimental Model System of Acute Meningitis and Hepatitis
Published in Experimental and molecular pathology (01-08-2001)“…Infection with mouse hepatitis virus (MHV) strain A59 produces acute hepatitis, encephalitis, and chronic demyelination in mice. However, little is known about…”
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The virulence of mouse hepatitis virus strain A59 is not dependent on efficient spike protein cleavage and cell-to-cell fusion
Published in Journal of neurovirology (01-10-2002)“…The cleavage and fusion properties of recombinant murine hepatitis viruses (MHV) were examined to assess the role of the cleavage signal in determining the…”
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The Spike Protein of Murine Coronavirus Mouse Hepatitis Virus Strain A59 Is Not Cleaved in Primary Glial Cells and Primary Hepatocytes
Published in Journal of Virology (01-02-1998)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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MHV-A59 fusion mutants are attenuated and display altered hepatotropism
Published in Virology (New York, N.Y.) (01-04-1994)“…Mouse hepatitis virus strain A59 causes a persistent productive, but nonlytic, infection of cultured glial cells. We have mutants isolated from persistently…”
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Nidoviruses
Published in The Quarterly Review of Biology (01-06-2009)“…Hingley reviews NIDOVIRUSES edited by Stanley Perlman, Thomas Gallagher and Eric J. Snijder…”
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Book Review