Search Results - "HINGLEY, Susan T"

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    Chlamydia pneumoniae : An Etiologic Agent for Late-Onset Dementia by Balin, Brian J, Hammond, Christine J, Little, Christopher Scott, Hingley, Susan T, Al-Atrache, Zein, Appelt, Denah M, Whittum-Hudson, Judith A, Hudson, Alan P

    Published in Frontiers in aging neuroscience (09-10-2018)
    “…The disease known as late-onset Alzheimer's disease is a neurodegenerative condition recognized as the single most commonform of senile dementia. The condition…”
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    Journal Article
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    Endosomal Proteolysis by Cathepsins Is Necessary for Murine Coronavirus Mouse Hepatitis Virus Type 2 Spike-Mediated Entry by ZHAOZHU QIU, HINGLEY, Susan T, SIMMONS, Graham, YU, Christopher, DAS SARMA, Jayasri, BATES, Paul, WEISS, Susan R

    Published in Journal of Virology (01-06-2006)
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    Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease by Al-Atrache, Zein, Lopez, Danielle B, Hingley, Susan T, Appelt, Denah M

    Published in BMC neuroscience (20-02-2019)
    “…Epidemiologic studies strongly suggest that the pathophysiology of late-onset Alzheimer disease (AD) versus early-onset AD has environmental rather than…”
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  4. 4

    Experimental Optic Neuritis Induced by a Demyelinating Strain of Mouse Hepatitis Virus by SHINDLER, Kenneth S, KENYON, Lawrence C, DUTT, Mahasweta, HINGLEY, Susan T, DAS SARMA, Jayasri

    Published in Journal of Virology (01-09-2008)
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  5. 5

    Gliopathy of Demyelinating and Non-Demyelinating Strains of Mouse Hepatitis Virus by Kenyon, Lawrence C, Biswas, Kaushiki, Shindler, Kenneth S, Nabar, Manasi, Stout, Marjorie, Hingley, Susan T, Grinspan, Judith B, Das Sarma, Jayasri

    Published in Frontiers in cellular neuroscience (22-12-2015)
    “…Demyelination in the central nervous system induced by neurovirulent strains of Mouse Hepatitis Virus (MHV) is mediated by the viral spike glycoprotein, but it…”
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  6. 6

    Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of [beta]-amyloid found in Alzheimer disease by Al-Atrache, Zein, Lopez, Danielle B, Hingley, Susan T, Appelt, Denah M

    Published in BMC neuroscience (20-02-2019)
    “…Background Epidemiologic studies strongly suggest that the pathophysiology of late-onset Alzheimer disease (AD) versus early-onset AD has environmental rather…”
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    Journal Article
  7. 7

    Chlamydia pneumoniae infection of monocytes in vitro stimulates innate and adaptive immune responses relevant to those in Alzheimer's disease by Lim, Charles, Hammond, Christine J, Hingley, Susan T, Balin, Brian J

    Published in Journal of neuroinflammation (24-12-2014)
    “…Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which infection with Chlamydia pneumoniae (Cpn) has been associated. Cpn is an obligate…”
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  8. 8

    Murine Coronavirus Evolution In Vivo: Functional Compensation of a Detrimental Amino Acid Substitution in the Receptor Binding Domain of the Spike Glycoprotein by NAVAS-MARTIN, Sonia, HINGLEY, Susan T, WEISS, Susan R

    Published in Journal of Virology (01-06-2005)
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  9. 9

    Mechanisms of Primary Axonal Damage in a Viral Model of Multiple Sclerosis by Das Sarma, Jayasri, Kenyon, Lawrence C, Hingley, Susan T, Shindler, Kenneth S

    Published in The Journal of neuroscience (19-08-2009)
    “…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Recent studies have demonstrated that significant axonal injury also occurs in MS…”
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    Sequence analysis of the S gene of recombinant MHV-2/A59 coronaviruses reveals three candidate mutations associated with demyelination and hepatitis by Das Sarma, Li Fu, Susan T. Hingley, Michael M. C. Lai, Ehud Lavi, Jayasri

    Published in Journal of neurovirology (01-10-2001)
    “…Coronaviruses, mouse hepatitis virus (MHV) strains, exhibit various degrees of neurotropism and hepatotropism following intracerebral (IC) infection of…”
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    Murine Coronavirus Spike Protein Determines the Ability of the Virus To Replicate in the Liver and Cause Hepatitis by Navas, S, Seo, S H, Chua, M M, Das Sarma, J, Lavi, E, Hingley, S T, Weiss, S R

    Published in Journal of Virology (01-03-2001)
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    Targeted Recombination within the Spike Gene of Murine Coronavirus Mouse Hepatitis Virus-A59: Q159 Is a Determinant of Hepatotropism by Leparc-Goffart, I, Hingley, S T, Chua, M M, Phillips, J, Lavi, E, Weiss, S R

    Published in Journal of Virology (01-12-1998)
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  16. 16

    Mouse Hepatitis Virus Type-2 Infection in Mice: An Experimental Model System of Acute Meningitis and Hepatitis by Sarma, Jayasri Das, Fu, Li, Hingley, Susan T., Lavi, Ehud

    Published in Experimental and molecular pathology (01-08-2001)
    “…Infection with mouse hepatitis virus (MHV) strain A59 produces acute hepatitis, encephalitis, and chronic demyelination in mice. However, little is known about…”
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    The virulence of mouse hepatitis virus strain A59 is not dependent on efficient spike protein cleavage and cell-to-cell fusion by Hingley, Susan T, Leparc-Goffart, Isabelle, Seo, Su-Hun, Tsai, Jean C, Weiss, Susan R

    Published in Journal of neurovirology (01-10-2002)
    “…The cleavage and fusion properties of recombinant murine hepatitis viruses (MHV) were examined to assess the role of the cleavage signal in determining the…”
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    The Spike Protein of Murine Coronavirus Mouse Hepatitis Virus Strain A59 Is Not Cleaved in Primary Glial Cells and Primary Hepatocytes by Hingley, S T, Leparc-Goffart, I, Weiss, S R

    Published in Journal of Virology (01-02-1998)
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    MHV-A59 fusion mutants are attenuated and display altered hepatotropism by Hingley, S T, Gombold, J L, Lavi, E, Weiss, S R

    Published in Virology (New York, N.Y.) (01-04-1994)
    “…Mouse hepatitis virus strain A59 causes a persistent productive, but nonlytic, infection of cultured glial cells. We have mutants isolated from persistently…”
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    Nidoviruses by Hingley, Susan T.

    Published in The Quarterly Review of Biology (01-06-2009)
    “…Hingley reviews NIDOVIRUSES edited by Stanley Perlman, Thomas Gallagher and Eric J. Snijder…”
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    Book Review