Search Results - "HINEY, Jill K"
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IGF-1 Influences Gonadotropin-Releasing Hormone Regulation of Puberty
Published in Neuroendocrinology (01-11-2021)“…The pubertal process is initiated as a result of complex neuroendocrine interactions within the preoptic and hypothalamic regions of the brain. These…”
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Influences of manganese on pubertal development
Published in Journal of endocrinology (01-10-2017)“…The onset of puberty is the result of complex neuroendocrine interactions within hypothalamic region of the brain, as well as from genetic and environmental…”
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3
Manganese induces IGF-1 and cyclooxygenase-2 gene expressions in the basal hypothalamus during prepubertal female development
Published in Toxicological sciences (01-06-2011)“…Precocious puberty is a significant child health problem, especially in girls, because 95% of cases are idiopathic. Our earlier studies demonstrated that…”
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Manganese Acts Centrally to Stimulate Luteinizing Hormone Secretion: A Potential Influence on Female Pubertal Development
Published in Toxicological sciences (01-06-2005)“…Manganese (Mn), an essential element considered important for normal growth and reproduction, has been shown in adults to be detrimental to reproductive…”
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5
Manganese stimulates luteinizing hormone releasing hormone secretion in prepubertal female rats: hypothalamic site and mechanism of action
Published in The Journal of physiology (01-02-2007)“…We have shown recently that Mn 2+ stimulates gonadotropin secretion via an action at the hypothalamic level, and a diet supplemented with a low dose of the…”
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How alcohol affects insulin‐like growth factor‐1's influences on the onset of puberty: A critical review
Published in Alcoholism, clinical and experimental research (01-11-2021)“…Alcohol (ALC) is capable of delaying signs associated with pubertal development in laboratory animals, as well as in humans. The normal onset of puberty…”
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Manganese-Stimulated Kisspeptin Is Mediated by the IGF-1/Akt/Mammalian Target of Rapamycin Pathway in the Prepubertal Female Rat
Published in Endocrinology (Philadelphia) (01-08-2016)“…Low-dose administration of manganese chloride (MnCl2) causes release of hypothalamic LH-releasing hormone (LHRH) and advances puberty in rat. Recently, this…”
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8
Regulation of prepubertal dynorphin secretion in the medial basal hypothalamus of the female rat
Published in Journal of neuroendocrinology (01-12-2019)“…The onset of puberty is the result of an increase in secretion of hypothalamic gonadotrophin‐releasing hormone (GnRH). This action is a result of not only the…”
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Alcohol Delays the Onset of Puberty in the Female Rat by Altering Key Hypothalamic Events
Published in Alcoholism, clinical and experimental research (01-07-2018)“…Background Because alcohol (ALC) delays signs of pubertal development, we assessed the time course of events associated with the synthesis of critical…”
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Regulation of Kisspeptin Synthesis and Release in the Preoptic/Anterior Hypothalamic Region of Prepubertal Female Rats: Actions of IGF‐1 and Alcohol
Published in Alcoholism, clinical and experimental research (01-01-2018)“…Background Alcohol (ALC) causes suppressed secretion of prepubertal luteinizing hormone‐releasing hormone (LHRH). Insulin‐like growth factor‐1 (IGF‐1) and…”
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Differential Effects of Alcohol on Excitatory and Inhibitory Puberty-Related Peptides in the Basal Hypothalamus of the Female Rat
Published in Alcoholism, clinical and experimental research (01-12-2015)“…Background An increase in development of excitatory inputs along with a decline in inhibitory inputs ultimately govern the timely increased secretion of…”
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Insulin-Like Growth Factor-I Activates KiSS-1 Gene Expression in the Brain of the Prepubertal Female Rat
Published in Endocrinology (Philadelphia) (01-01-2009)“…KiSS-1 gene expression has been shown to increase as puberty approaches, and its peptide products, kisspeptins, are involved in LHRH secretion at puberty…”
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13
Early life manganese exposure upregulates tumor-associated genes in the hypothalamus of female rats: relationship to manganese-induced precocious puberty
Published in Toxicological sciences (01-12-2013)“…Prepubertal exposure to low, but elevated levels of manganese (Mn) can induce increased secretions of puberty-related hormones resulting in precocious pubertal…”
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Manganese protects against the effects of alcohol on hypothalamic puberty-related hormones
Published in Life sciences (1973) (01-03-2016)“…Since manganese (Mn) is capable of stimulating the hypothalamic-pituitary unit and advancing female puberty, we assessed the possibility that this element…”
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Actions and Interactions of Alcohol and Transforming Growth Factor β1 on Prepubertal Hypothalamic Gonadotropin-Releasing Hormone
Published in Alcoholism, clinical and experimental research (01-05-2014)“…Background Alcohol (ALC) diminishes gonadotropin‐releasing hormone (GnRH) secretion and delays puberty. Glial transforming growth factor β1 (TGFβ1) plays a…”
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Alcohol Alters Insulin-Like Growth Factor-1-Induced Transforming Growth Factor β1 Synthesis in the Medial Basal Hypothalamus of the Prepubertal Female Rat
Published in Alcoholism, clinical and experimental research (01-10-2014)“…Background Insulin‐like growth factor‐1 (IGF‐1) and transforming growth factor β1 (TGFβ1) are produced in hypothalamic astrocytes and facilitate luteinizing…”
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Alcohol Alters Insulin-Like Growth Factor-1-Induced Transforming Growth Factor beta 1 Synthesis in the Medial Basal Hypothalamus of the Prepubertal Female Rat
Published in Alcoholism, clinical and experimental research (01-10-2014)“…Insulin-like growth factor-1 (IGF-1) and transforming growth factor beta 1 (TGF beta 1) are produced in hypothalamic astrocytes and facilitate luteinizing…”
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Actions and Interactions of Alcohol and Transforming Growth Factor β 1 on Prepubertal Hypothalamic Gonadotropin‐Releasing Hormone
Published in Alcoholism, clinical and experimental research (01-05-2014)“…Background Alcohol ( ALC ) diminishes gonadotropin‐releasing hormone ( G n RH ) secretion and delays puberty. Glial transforming growth factor β 1 ( TGF β 1)…”
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Effect of ethanol on follicle stimulating hormone-induced steroidogenic acute regulatory protein (StAR) in cultured rat granulosa cells
Published in Alcohol (Fayetteville, N.Y.) (01-10-2005)“…Steroidogenic acute regulatory protein (StAR) plays a critical role in trophic hormone-stimulated steroid biosynthesis by facilitating the transfer of…”
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The Pyrethroid Pesticide Esfenvalerate Suppresses the Afternoon Rise of Luteinizing Hormone and Delays Puberty in Female Rats
Published in Environmental health perspectives (01-09-2008)“…Background: One of the most widely used classes of insecticides is the synthetic pyrethroids. Although pyrethroids are less acutely toxic to humans than to…”
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