Search Results - "HINDS, A"

minimac2: faster genotype imputation by Fuchsberger, Christian, Abecasis, Gonçalo R, Hinds, David A

“…Genotype imputation is a key step in the analysis of genome-wide association studies. Upcoming very large reference panels, such as those from The 1000 Genomes…”
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Experiment to Detect Dark Energy Forces Using Atom Interferometry by Sabulsky, D O, Dutta, I, Hinds, E A, Elder, B, Burrage, C, Copeland, Edmund J

“…The accelerated expansion of the universe motivates a wide class of scalar field theories that modify general relativity (GR) on large scales. Such theories…”
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Detection and interpretation of shared genetic influences on 42 human traits by Pickrell, Joseph K, Berisa, Tomaz, Liu, Jimmy Z, Ségurel, Laure, Tung, Joyce Y, Hinds, David A

“…Joseph Pickrell and colleagues analyze genome-wide association data for 42 human phenotypes or diseases and identify several hundred loci influencing multiple…”
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Magnetic Trapping and Coherent Control of Laser-Cooled Molecules by Williams, H J, Caldwell, L, Fitch, N J, Truppe, S, Rodewald, J, Hinds, E A, Sauer, B E, Tarbutt, M R

“…We demonstrate coherent microwave control of the rotational, hyperfine, and Zeeman states of ultracold CaF molecules, and the magnetic trapping of these…”
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GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person by Hu, Youna, Shmygelska, Alena, Tran, David, Eriksson, Nicholas, Tung, Joyce Y., Hinds, David A.

“…Circadian rhythms are a nearly universal feature of living organisms and affect almost every biological process. Our innate preference for mornings or evenings…”
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Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections by Tian, Chao, Hromatka, Bethann S., Kiefer, Amy K., Eriksson, Nicholas, Noble, Suzanne M., Tung, Joyce Y., Hinds, David A.

“…Infectious diseases have a profound impact on our health and many studies suggest that host genetics play a major role in the pathogenesis of most of them. We…”
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Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct by Ferreira, Manuel A.R., Mathur, Riddhima, Vonk, Judith M., Szwajda, Agnieszka, Brumpton, Ben, Granell, Raquel, Brew, Bronwyn K., Ullemar, Vilhelmina, Lu, Yi, Jiang, Yunxuan, Magnusson, Patrik K.E., Karlsson, Robert, Hinds, David A., Paternoster, Lavinia, Koppelman, Gerard H., Almqvist, Catarina

“…The extent to which genetic risk factors are shared between childhood-onset (COA) and adult-onset (AOA) asthma has not been estimated. On the basis of data…”
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Laser Cooled YbF Molecules for Measuring the Electron's Electric Dipole Moment by Lim, J, Almond, J R, Trigatzis, M A, Devlin, J A, Fitch, N J, Sauer, B E, Tarbutt, M R, Hinds, E A

“…We demonstrate one-dimensional sub-Doppler laser cooling of a beam of YbF molecules to 100  μK. This is a key step towards a measurement of the electron's…”
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Improved measurement of the shape of the electron by Hudson, J. J., Kara, D. M., Smallman, I. J., Sauer, B. E., Tarbutt, M. R., Hinds, E. A.

“…How round is the electron? The electron is spherical — well, nearly. The standard model of particle physics predicts a slightly aspheric electron, with a…”
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Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms by Hinds, David A., Barnholt, Kimberly E., Mesa, Ruben A., Kiefer, Amy K., Do, Chuong B., Eriksson, Nicholas, Mountain, Joanna L., Francke, Uta, Tung, Joyce Y., Nguyen, Huong (Marie), Zhang, Haiyu, Gojenola, Linda, Zehnder, James L., Gotlib, Jason

“…We conducted a genome-wide association study (GWAS) to identify novel predisposition alleles associated with Philadelphia chromosome-negative…”
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Genome-wide analysis points to roles for extracellular matrix remodeling, the visual cycle, and neuronal development in myopia by Kiefer, Amy K, Tung, Joyce Y, Do, Chuong B, Hinds, David A, Mountain, Joanna L, Francke, Uta, Eriksson, Nicholas

“…Myopia, or nearsightedness, is the most common eye disorder, resulting primarily from excess elongation of the eye. The etiology of myopia, although known to…”
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An intense, cold, velocity-controlled molecular beam by frequency-chirped laser slowing by Truppe, S, Williams, H J, Fitch, N J, Hambach, M, Wall, T E, Hinds, E A, Sauer, B E, Tarbutt, M R

“…Using frequency-chirped radiation pressure slowing, we precisely control the velocity of a pulsed CaF molecular beam down to a few m s-1, compressing its…”
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Comparison of family history and SNPs for predicting risk of complex disease by Do, Chuong B, Hinds, David A, Francke, Uta, Eriksson, Nicholas

“…The clinical utility of family history and genetic tests is generally well understood for simple Mendelian disorders and rare subforms of complex diseases that…”
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Characteristics of a magneto-optical trap of molecules by Williams, H J, Truppe, S, Hambach, M, Caldwell, L, Fitch, N J, Hinds, E A, Sauer, B E, Tarbutt, M R

“…We present the properties of a magneto-optical trap (MOT) of CaF molecules. We study the process of loading the MOT from a decelerated buffer-gas-cooled beam,…”
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Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci by Jones, Samuel E, Tyrrell, Jessica, Wood, Andrew R, Beaumont, Robin N, Ruth, Katherine S, Tuke, Marcus A, Yaghootkar, Hanieh, Hu, Youna, Teder-Laving, Maris, Hayward, Caroline, Roenneberg, Till, Wilson, James F, Del Greco, Fabiola, Hicks, Andrew A, Shin, Chol, Yun, Chang-Ho, Lee, Seung Ku, Metspalu, Andres, Byrne, Enda M, Gehrman, Philip R, Tiemeier, Henning, Allebrandt, Karla V, Freathy, Rachel M, Murray, Anna, Hinds, David A, Frayling, Timothy M, Weedon, Michael N

“…Disrupted circadian rhythms and reduced sleep duration are associated with several human diseases, particularly obesity and type 2 diabetes, but until…”
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Design for a fountain of YbF molecules to measure the electron's electric dipole moment by Tarbutt, M R, Sauer, B E, Hudson, J J, Hinds, E A

“…We propose an experiment to measure the electric dipole moment (EDM) of the electron using ultracold YbF molecules. The molecules are produced as a thermal…”
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Genetic Associations with Gestational Duration and Spontaneous Preterm Birth by Zhang, Ge, Feenstra, Bjarke, Bacelis, Jonas, Liu, Xueping, Muglia, Lisa M, Juodakis, Julius, Miller, Daniel E, Litterman, Nadia, Jiang, Pan-Pan, Russell, Laura, Hinds, David A, Hu, Youna, Weirauch, Matthew T, Chen, Xiaoting, Chavan, Arun R, Wagner, Günter P, Pavličev, Mihaela, Nnamani, Mauris C, Maziarz, Jamie, Karjalainen, Minna K, Rämet, Mika, Sengpiel, Verena, Geller, Frank, Boyd, Heather A, Palotie, Aarno, Momany, Allison, Bedell, Bruce, Ryckman, Kelli K, Huusko, Johanna M, Forney, Carmy R, Kottyan, Leah C, Hallman, Mikko, Teramo, Kari, Nohr, Ellen A, Davey Smith, George, Melbye, Mads, Jacobsson, Bo, Muglia, Louis J

“…In a genomewide association study, variants at three loci — EBF1, EEFSEC, and AGTR2 — were associated with both gestational duration and preterm birth…”
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Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis by Gallagher, C. S., Mäkinen, N., Harris, H. R., Rahmioglu, N., Uimari, O., Cook, J. P., Shigesi, N., Ferreira, T., Velez-Edwards, D. R., Edwards, T. L., Mortlock, S., Ruhioglu, Z., Day, F., Becker, C. M., Karhunen, V., Martikainen, H., Järvelin, M.-R., Cantor, R. M., Ridker, P. M., Terry, K. L., Buring, J. E., Gordon, S. D., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Hinds, D. A., Tung, J. Y., Perry, J. R. B., Lind, P. A., Painter, J. N., Martin, N. G., Morris, A. P., Chasman, D. I., Missmer, S. A., Zondervan, K. T., Morton, C. C.

“…Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract and primary cause for hysterectomy, leading to considerable morbidity…”
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Novel associations for hypothyroidism include known autoimmune risk loci by Eriksson, Nicholas, Tung, Joyce Y, Kiefer, Amy K, Hinds, David A, Francke, Uta, Mountain, Joanna L, Do, Chuong B

“…Hypothyroidism is the most common thyroid disorder, affecting about 5% of the general population. Here we present the current largest genome-wide association…”
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The Role of the Hypothalamus–Pituitary–Adrenal (HPA) Axis in Test-Induced Anxiety: Assessments, Physiological Responses, and Molecular Details by Hinds, Jenalee A., Sanchez, Edwin R.

“…Test anxiety may be a contributing factor to low-performing examination scores among students. There can be numerous physiological responses in the body that…”
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