Search Results - "HINCHCLIFFE, Michael"

Distribution of Droplets and Immune Responses After Aerosol and Intra-Nasal Delivery of Influenza Virus to the Respiratory Tract of Pigs by Martini, Veronica, Hinchcliffe, Michael, Blackshaw, Elaine, Joyce, Mary, McNee, Adam, Beverley, Peter, Townsend, Alain, MacLoughlin, Ronan, Tchilian, Elma

“…Recent evidence indicates that local immune responses and tissue resident memory T cells (T ) are critical for protection against respiratory infections but…”
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Nasal Administration and Plasma Pharmacokinetics of Parathyroid Hormone Peptide PTH 1-34 for the Treatment of Osteoporosis by Pearson, Richard G, Masud, Tahir, Blackshaw, Elaine, Naylor, Andrew, Hinchcliffe, Michael, Jeffery, Kirk, Jordan, Faron, Shabir-Ahmed, Anjumn, King, Gareth, Lewis, Andrew L, Illum, Lisbeth, Perkins, Alan C

“…Nasal delivery of large peptides such as parathyroid 1-34 (PTH 1-34) can benefit from a permeation enhancer to promote absorption across the nasal mucosa into…”
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Intranasal H5N1 vaccines, adjuvanted with chitosan derivatives, protect ferrets against highly pathogenic influenza intranasal and intratracheal challenge by Mann, Alex J, Noulin, Nicolas, Catchpole, Andrew, Stittelaar, Koert J, de Waal, Leon, Veldhuis Kroeze, Edwin J B, Hinchcliffe, Michael, Smith, Alan, Montomoli, Emanuele, Piccirella, Simona, Osterhaus, Albert D M E, Knight, Alastair, Oxford, John S, Lapini, Giulia, Cox, Rebecca, Lambkin-Williams, Rob

“…We investigated the protective efficacy of two intranasal chitosan (CSN and TM-CSN) adjuvanted H5N1 Influenza vaccines against highly pathogenic avian…”
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Effect of chitosan on the intranasal absorption of salmon calcitonin in sheep by Hinchcliffe, Michael, Jabbal-Gill, Inderjit, Smith, Alan

“…The effects of a chitosan‐based delivery system on the pharmacokinetics of intranasally administered salmon calcitonin (sCT) were investigated in a sheep…”
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Mathematical Modeling and Optimization of Drug Delivery from Intratumorally Injected Microspheres by TZAFRIRI, Abraham Rami, LERNER, Elyakum Itzhak, FLASHNER-BARAK, Moshe, HINCHCLIFFE, Michael, RATNER, Eli, PARNAS, Hanna

“…Purpose: Paclitaxel is a highly promising phase-sensitive antitumor drug that could conceivably be improved by extended lower dosing as opposed to intermittent…”
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Intranasal delivery of recombinant human growth hormone (somatropin) in sheep using chitosan-based powder formulations by Cheng, Yu-Hui, Dyer, A. Margaret, Jabbal-Gill, Inderjit, Hinchcliffe, Michael, Nankervis, Richard, Smith, Alan, Watts, Peter

“…The effectiveness of chitosan in promoting the intranasal bioavailability of recombinant human growth hormone (hGH) has been evaluated. hGH was formulated with…”
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Riluzole: real-world evidence supports significant extension of median survival times in patients with amyotrophic lateral sclerosis by Hinchcliffe, Michael, Smith, Alan

“…Amyotrophic lateral sclerosis (ALS) is the commonest form of motor neuron disease and is a fatal, degenerative, multisystem disorder affecting upper and/or…”
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Chitosan: A promising safe and immune-enhancing adjuvant for intranasal vaccines by Smith, Alan, Perelman, Michael, Hinchcliffe, Michael

“…The nasal route is attractive for the delivery of vaccines in that it not only offers an easy to use, non-invasive, needle-free alternative to more…”
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Gamma-scintigraphy as a novel method to study the distribution and retention of a bioadhesive vaginal delivery system in sheep by Richardson, Julie L., Whetstone, Joanne, Fisher, Anthony N., Watts, Peter, Farraj, Nidal F., Hinchcliffe, Michael, Benedetti, Luca, Illum, Lisbeth

“…The distribution and the retention time of a novel bioadhesive intravaginal delivery system based on HYAFF microspheres were studied in a sheep model. In a…”
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Intranasal insulin delivery and therapy by Hinchcliffe, Michael, Illum, Lisbeth

“…Intranasal insulin delivery has been widely investigated as an alternative to subcutaneous injection for the treatment of diabetes. The pharmacokinetic profile…”
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A study of Chitosan and c‐di‐GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine by Svindland, Signe C., Pedersen, Gabriel K., Pathirana, Rishi D., Bredholt, Geir, Nøstbakken, Jane K., Jul‐Larsen, Åsne, Guzmán, Carlos A., Montomoli, Emanuele, Lapini, Giulia, Piccirella, Simona, Jabbal‐Gill, Inderjit, Hinchcliffe, Michael, Cox, Rebecca J.

“…Please cite this paper as: Svindland et al. (2012) A study of Chitosan and c‐di‐GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine. Influenza and…”
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Intranasal H5N1 Vaccines, Adjuvanted with Chitosan Derivatives, Protect Ferrets against Highly Pathogenic Influenza Intranasal and Intratracheal Challenge: e93761 by Mann, Alex J, Noulin, Nicolas, Catchpole, Andrew, Stittelaar, Koert J, Waal, Leon de, Kroeze, J BVeldhuis, Hinchcliffe, Michael, Smith, Alan, Montomoli, Emanuele, Piccirella, Simona

“…We investigated the protective efficacy of two intranasal chitosan (CSN and TM-CSN) adjuvanted H5N1 Influenza vaccines against highly pathogenic avian…”
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Intranasal insulin delivery and therapy1Abbreviations: α-CD, α-cyclodextrin; β-CD, β-cyclodextrin; γ-CD, γ-cyclodextrin; AUC, area under the plasma/serum concentration versus time curve; Cmax, maximum or peak plasma/serum concentration; Cmin, minimum plasma/serum concentration; DDPC, didecanoyl-L-α-phosphatidylcholine; DM-β-CD, dimethyl-β-cyclodextrin; EDTA, ethylenediaminetetraacetic acid; FITC, fluorescein isothiocyanate; HLB, hydrophile–lipophile balance; hGH, human growth hormone; HP-β-CD, h by Hinchcliffe, Michael, Illum, Lisbeth

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RiVGRu 1 increases command, control with new RCB boat by Hinchcliffe, Michael R

“…Riverine Group 1 is testing its first Riverine Command Boat, which gives Riverine squandrons the ability to travel not only in rivers, but also out to bays and…”
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KIPLING'S VISION OF ENGLAND: A STUDY OF HIS USE OF THE HISTORICAL IMAGINATION by HINCHCLIFFE, PETER MICHAEL DOMINIC

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