Search Results - "HILLSON, Nathan J"
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j5 DNA Assembly Design Automation Software
Published in ACS synthetic biology (20-01-2012)“…Recent advances in Synthetic Biology have yielded standardized and automatable DNA assembly protocols that enable a broad range of biotechnological research…”
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The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology
Published in Nature biotechnology (01-06-2014)“…The synthetic biology research community describes a standard language for exchanging designs of biological 'parts'. The re-use of previously validated designs…”
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Repurposing a microfluidic formulation device for automated DNA construction
Published in PloS one (11-11-2020)“…Microfluidic applications have expanded greatly over the past decade. For the most part, however, each microfluidics platform is developed with a specific task…”
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Lessons from Two Design–Build–Test–Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning
Published in ACS synthetic biology (21-06-2019)“…The Design–Build–Test–Learn (DBTL) cycle, facilitated by exponentially improving capabilities in synthetic biology, is an increasingly adopted metabolic…”
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Principal component analysis of proteomics (PCAP) as a tool to direct metabolic engineering
Published in Metabolic engineering (01-03-2015)“…Targeted proteomics is a convenient method determining enzyme expression levels, but a quantitative analysis of these proteomic data has not been fully…”
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Fluorescent amplification for next generation sequencing (FA-NGS) library preparation
Published in BMC genomics (28-01-2020)“…Next generation sequencing (NGS) has become a universal practice in modern molecular biology. As the throughput of sequencing experiments increases, the…”
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Engineering of Ralstonia eutropha H16 for Autotrophic and Heterotrophic Production of Methyl Ketones
Published in Applied and Environmental Microbiology (01-07-2013)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Modular automated bottom-up proteomic sample preparation for high-throughput applications
Published in PloS one (25-02-2022)“…Manual proteomic sample preparation methods limit sample throughput and often lead to poor data quality when thousands of samples must be analyzed. Automated…”
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Cloud-enabled microscopy and droplet microfluidic platform for specific detection of Escherichia coli in water
Published in PloS one (27-01-2014)“…We report an all-in-one platform - ScanDrop - for the rapid and specific capture, detection, and identification of bacteria in drinking water. The ScanDrop…”
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Development of a broad-host synthetic biology toolbox for Ralstonia eutropha and its application to engineering hydrocarbon biofuel production
Published in Microbial cell factories (13-11-2013)“…The chemoautotrophic bacterium Ralstonia eutropha can utilize H2/CO2 for growth under aerobic conditions. While this microbial host has great potential to be…”
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Jungle Express is a versatile repressor system for tight transcriptional control
Published in Nature communications (06-09-2018)“…Tightly regulated promoters are essential for numerous biological applications, where strong inducibility, portability, and scalability are desirable. Current…”
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SBOL Visual: A Graphical Language for Genetic Designs
Published in PLoS biology (01-12-2015)“…Synthetic Biology Open Language (SBOL) Visual is a graphical standard for genetic engineering. It consists of symbols representing DNA subsequences, including…”
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Ten simple rules for managing laboratory information
Published in PLoS computational biology (01-12-2023)“…Information is the cornerstone of research, from experimental (meta)data and computational processes to complex inventories of reagents and equipment. These 10…”
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Oxidative cyclization of prodigiosin by an alkylglycerol monooxygenase-like enzyme
Published in Nature chemical biology (01-11-2017)“…In Pseudoalteromonas rubra , an unclustered biosynthetic gene encodes a di-iron oxygenase-like enzyme that catalyzes regiospecific C–H activation and…”
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plant glycosyltransferase clone collection for functional genomics
Published in The Plant journal : for cell and molecular biology (01-08-2014)“…The glycosyltransferases (GTs) are an important and functionally diverse family of enzymes involved in glycan and glycoside biosynthesis. Plants have evolved…”
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Investigation of Proposed Ladderane Biosynthetic Genes from Anammox Bacteria by Heterologous Expression in E. coli
Published in PloS one (14-03-2016)“…Ladderanes are hydrocarbon chains with three or five linearly concatenated cyclobutane rings that are uniquely produced as membrane lipid components by anammox…”
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Cell pole—specific activation of a critical bacterial cell cycle kinase
Published in Proceedings of the National Academy of Sciences - PNAS (13-04-2010)“…Caulobacter crescentus integrates phospho-signaling pathways and transcription factor regulatory cascades to drive the cell cycle. Despite the essential role…”
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Proposed design of distributed macroalgal biorefineries: thermodynamics, bioconversion technology, and sustainability implications for developing economies
Published in Biofuels, bioproducts and biorefining (01-01-2014)“…Biomass to fuel programs are under research and development worldwide. The largest biomass programs are underway in industrialized countries. In the coming…”
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DeviceEditor visual biological CAD canvas
Published in Journal of biological engineering (28-02-2012)“…Biological Computer Aided Design (bioCAD) assists the de novo design and selection of existing genetic components to achieve a desired biological activity, as…”
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The Experiment Data Depot: A Web-Based Software Tool for Biological Experimental Data Storage, Sharing, and Visualization
Published in ACS synthetic biology (15-12-2017)“…Although recent advances in synthetic biology allow us to produce biological designs more efficiently than ever, our ability to predict the end result of these…”
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