Search Results - "HILL, Victoria K"

Tumor-specific hypermethylation of epigenetic biomarkers, including SFRP1, predicts for poorer survival in patients from the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) project by Ricketts, Christopher J, Hill, Victoria K, Linehan, W Marston

“…The recent publication of the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) project has provided an immense wealth and breadth of data providing an invaluable…”
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Recurrent inactivating RASA2 mutations in melanoma by Arafeh, Rand, Qutob, Nouar, Emmanuel, Rafi, Keren-Paz, Alona, Madore, Jason, Elkahloun, Abdel, Wilmott, James S, Gartner, Jared J, Di Pizio, Antonella, Winograd-Katz, Sabina, Sindiri, Sivasish, Rotkopf, Ron, Dutton-Regester, Ken, Johansson, Peter, Pritchard, Antonia L, Waddell, Nicola, Hill, Victoria K, Lin, Jimmy C, Hevroni, Yael, Rosenberg, Steven A, Khan, Javed, Ben-Dor, Shifra, Niv, Masha Y, Ulitsky, Igor, Mann, Graham J, Scolyer, Richard A, Hayward, Nicholas K, Samuels, Yardena

“…Yardena Samuels and colleagues report the analysis of 501 melanoma exomes and the identification of RASA2 as a tumor-suppressor gene mutated in 5% of…”
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Correction of PTEN mutations in glioblastoma cell lines via AAV-mediated gene editing by Hill, Victoria K, Kim, Jung-Sik, James, C David, Waldman, Todd

“…PTEN is among the most commonly mutated tumor suppressor genes in human cancer. However, studying the role of PTEN in the pathogenesis of cancer has been…”
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DNA methylation profiles of long- and short-term glioblastoma survivors by Shinawi, Thoraia, Hill, Victoria K, Krex, Dietmar, Schackert, Gabriele, Gentle, Dean, Morris, Mark R, Wei, Wenbin, Cruickshank, Garth, Maher, Eamonn R, Latif, Farida

“…Glioblastoma (GBM) is the most common and malignant type of primary brain tumor in adults and prognosis of most GBM patients is poor. However, a small…”
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Identification of 5 novel genes methylated in breast and other epithelial cancers by Hill, Victoria K, Hesson, Luke B, Dansranjavin, Temuujin, Dallol, Ashraf, Bieche, Ivan, Vacher, Sophie, Tommasi, Stella, Dobbins, Timothy, Gentle, Dean, Euhus, David, Lewis, Cheryl, Dammann, Reinhard, Ward, Robyn L, Minna, John, Maher, Eammon R, Pfeifer, Gerd P, Latif, Farida

“…There are several high throughput approaches to identify methylated genes in cancer. We utilized one such recently developed approach, MIRA (methylated-CpG…”
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Stability of the CpG island methylator phenotype during glioma progression and identification of methylated loci in secondary glioblastomas by Hill, Victoria K, Shinawi, Thoraia, Ricketts, Christopher J, Krex, Dietmar, Schackert, Gabriele, Bauer, Julien, Wei, Wenbin, Cruickshank, Garth, Maher, Eamonn R, Latif, Farida

“…Grade IV glioblastomas exist in two forms, primary (de novo) glioblastomas (pGBM) that arise without precursor lesions, and the less common secondary…”
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Cohesin mutations in human cancer by Hill, Victoria K., Kim, Jung-Sik, Waldman, Todd

“…Cohesin is a highly-conserved protein complex that plays important roles in sister chromatid cohesion, chromatin structure, gene expression, and DNA repair. In…”
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Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia by Hill, Victoria K., Dunwell, Thomas L., Catchpoole, Daniel, Krex, Dietmar, Brini, Anna T., Griffiths, Mike, Craddock, Charles, Maher, Eamonn R., Latif, Farida

“…The WW-domain containing protein KIBRA has recently been identified as a new member of the Salvador/Warts/Hippo (SWH) pathway in Drosophila and is shown to act…”
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Breast Cancers Are Immunogenic: Immunologic Analyses and a Phase II Pilot Clinical Trial Using Mutation-Reactive Autologous Lymphocytes by Zacharakis, Nikolaos, Huq, Lutfi M, Seitter, Samantha J, Kim, Sanghyun P, Gartner, Jared J, Sindiri, Sivasish, Hill, Victoria K, Li, Yong F, Paria, Biman C, Ray, Satyajit, Gasmi, Billel, Lee, Chyi-Chia, Prickett, Todd D, Parkhurst, Maria R, Robbins, Paul F, Langhan, Michelle M, Shelton, Thomas E, Parikh, Anup Y, Levi, Shoshana T, Hernandez, Jonathan M, Hoang, Chuong D, Sherry, Richard M, Yang, James C, Feldman, Steven A, Goff, Stephanie L, Rosenberg, Steven A

“…Metastatic breast cancer (mBrCa) is most often an incurable disease with only modest responses to available immunotherapies. This study investigates the…”
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Genome-Wide DNA Methylation Profiling of CpG Islands in Breast Cancer Identifies Novel Genes Associated with Tumorigenicity by HILL, Victoria K, RICKETTS, Christopher, BIECHE, Ivan, VACHER, Sophie, GENTLE, Dean, LEWIS, Cheryl, MAHER, Eamonn R, LATIF, Farida

“…Epigenetic profiling of tumor DNAs may reveal important new theranostic targets to improve prognosis and treatment of advanced cancer patients. In this study,…”
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Phenotypic signatures of circulating neoantigen-reactive CD8 + T cells in patients with metastatic cancers by Yossef, Rami, Krishna, Sri, Sindiri, Sivasish, Lowery, Frank J, Copeland, Amy R, Gartner, Jared J, Parkhurst, Maria R, Parikh, Neilesh B, Hitscherich, Kyle J, Levi, Shoshana T, Chatani, Praveen D, Zacharakis, Nikolaos, Levin, Noam, Vale, Nolan R, Nah, Shirley K, Dinerman, Aaron, Hill, Victoria K, Ray, Satyajit, Bera, Alakesh, Levy, Lior, Jia, Li, Kelly, Michael C, Goff, Stephanie L, Robbins, Paul F, Rosenberg, Steven A

“…Circulating T cells from peripheral blood (PBL) can provide a rich and noninvasive source for antitumor T cells. By single-cell transcriptomic profiling of 36…”
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The Genetics of Melanoma: Recent Advances by Hill, Victoria K, Gartner, Jared J, Samuels, Yardena, Goldstein, Alisa M

“…Cutaneous malignant melanoma results from the interplay of genetic, host, and environmental factors. Genetic factors implicated in melanoma etiology include…”
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Somatic Mutation of GRIN2A in Malignant Melanoma Results in Loss of Tumor Suppressor Activity via Aberrant NMDAR Complex Formation by Prickett, Todd D., Zerlanko, Brad J., Hill, Victoria K., Gartner, Jared J., Qutob, Nouar, Jiang, Jiji, Simaan, May, Wunderlich, John, Gutkind, J Silvio, Rosenberg, Steven A., Samuels, Yardena

“…The ionotropic glutamate receptors (N-methyl-D-aspartate receptors (NMDARs)) are composed of large complexes of multi-protein subunits creating ion channels in…”
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RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells by Qutob, Nouar, Masuho, Ikuo, Alon, Michal, Emmanuel, Rafi, Cohen, Isadora, Di Pizio, Antonella, Madore, Jason, Elkahloun, Abdel, Ziv, Tamar, Levy, Ronen, Gartner, Jared J., Hill, Victoria K., Lin, Jimmy C., Hevroni, Yael, Greenberg, Polina, Brodezki, Alexandra, Rosenberg, Steven A., Kosloff, Mickey, Hayward, Nicholas K., Admon, Arie, Niv, Masha Y., Scolyer, Richard A., Martemyanov, Kirill A., Samuels, Yardena

“…Analysis of 501 melanoma exomes revealed RGS7 , which encodes a GTPase-accelerating protein (GAP), to be a tumor-suppressor gene. RGS7 was mutated in 11% of…”
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Author Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells by Qutob, Nouar, Masuho, Ikuo, Alon, Michal, Emmanuel, Rafi, Cohen, Isadora, Di Pizio, Antonella, Madore, Jason, Elkahloun, Abdel, Ziv, Tamar, Levy, Ronen, Gartner, Jared J., Hill, Victoria K., Lin, Jimmy C., Hevroni, Yael, Greenberg, Polina, Brodezki, Alexandra, Rosenberg, Steven A., Kosloff, Mickey, Hayward, Nicholas K., Admon, Arie, Niv, Masha Y., Scolyer, Richard A., Martemyanov, Kirill A., Samuels, Yardena

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper…”
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Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers by Lowery, Frank J, Krishna, Sri, Yossef, Rami, Parikh, Neilesh B, Chatani, Praveen D, Zacharakis, Nikolaos, Parkhurst, Maria R, Levin, Noam, Sindiri, Sivasish, Sachs, Abraham, Hitscherich, Kyle J, Yu, Zhiya, Vale, Nolan R, Lu, Yong-Chen, Zheng, Zhili, Jia, Li, Gartner, Jared J, Hill, Victoria K, Copeland, Amy R, Nah, Shirley K, Masi, Robert V, Gasmi, Billel, Kivitz, Scott, Paria, Biman C, Florentin, Maria, Kim, Sanghyun P, Hanada, Ken-Ichi, Li, Yong F, Ngo, Lien T, Ray, Satyajit, Shindorf, Mackenzie L, Levi, Shoshana T, Shepherd, Ryan, Toy, Chris, Parikh, Anup Y, Prickett, Todd D, Kelly, Michael C, Beyer, Rachel, Goff, Stephanie L, Yang, James C, Robbins, Paul F, Rosenberg, Steven A

“…The accurate identification of antitumor T cell receptors (TCRs) represents a major challenge for the engineering of cell-based cancer immunotherapies. By…”
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Tumor-Specific Hypermethylation of Epigenetic Biomarkers, Including SFRP1, Predicts for Poorer Survival in Patients from the TCGA Kidney Renal Clear Cell Carcinoma by Ricketts, Christopher J, Hill, Victoria K, Linehan, W. Marston

“…The recent publication of the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) project has provided an immense wealth and breadth of data providing an invaluable…”
Get full text

Tumor-Specific Hypermethylation of Epigenetic Biomarkers, Including SFRP1, Predicts for Poorer Survival in Patients from the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) Project: e85621 by Ricketts, Christopher J, Hill, Victoria K, Linehan, W Marston

“…The recent publication of the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) project has provided an immense wealth and breadth of data providing an invaluable…”
Get full text

DNA methylation profiles of long- and short-term glioblastoma survivors by Shinawi, Thoraia, Hill, Victoria K., Krex, Dietmar, Schackert, Gabriele, Gentle, Dean, Morris, Mark R., Wei, Wenbin, Cruickshank, Garth, Maher, Eamonn R, Latif, Farida

“…Glioblastoma (GBM) is the most common and malignant type of primary brain tumor in adults and prognosis of most GBM patients is poor. However, a small…”
Get full text