Search Results - "HILBERT, Stephen L"

Performance and Morphology of Decellularized Pulmonary Valves Implanted in Juvenile Sheep by Quinn, Rachael W., PhD, Hilbert, Stephen L., MD, PhD, Bert, Arthur A., MD, Drake, Bill W., MD, Bustamante, Julie A., RN, Fenton, Jason E., RN, Moriarty, Sara J., BS, Neighbors, Stacy L., RNFA, Lofland, Gary K., MD, Hopkins, Richard A., MD

“…Background Because of cryopreserved heart valve–mediated immune responses, decellularized allograft valves are an attractive option in children and young…”
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Performance of allogeneic bioengineered replacement pulmonary valves in rapidly growing young lambs by Quinn, Rachael W., PhD, Bert, Arthur A., MD, Converse, Gabriel L., PhD, Buse, Eric E., MS (BME), Hilbert, Stephen L., PhD, MD, Drake, William B., MD, MS, Hopkins, Richard A., MD

“…Abstract Background Cardiac allometric organ growth after pediatric valve replacement can lead to patient–prosthesis size mismatch and valve re-replacement,…”
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Bioengineered human and allogeneic pulmonary valve conduits chronically implanted orthotopically in baboons: Hemodynamic performance and immunologic consequences by Hopkins, Richard A., MD, Bert, Arthur A., MD, Hilbert, Stephen L., PhD, MD, Quinn, Rachael W., PhD, Brasky, Kathleen M., VMD, Drake, William B., MD, Lofland, Gary K., MD

“…Objective This study assesses in a baboon model the hemodynamics and human leukocyte antigen immunogenicity of chronically implanted bioengineered…”
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Determining Cell Seeding Dosages for Tissue Engineering Human Pulmonary Valves by Frank, Benjamin S., B.S, Toth, Peter B., B.S, Wells, Whitney K., B.S, McFall, Christopher R., B.S, Cromwell, Michael L., B.S, Hilbert, Stephen L., M.D., Ph.D, Lofland, Gary K., M.D, Hopkins, Richard A., M.D

“…Background This study examines in vitro seeding of decellularized human pulmonary valves (hPVs) with human valve interstitial cells (hVICs) isolated from…”
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Cyclic pressure affects the biological properties of porcine aortic valve leaflets in a magnitude and frequency dependent manner by Xing, Yun, Warnock, James N, He, Zhaoming, Hilbert, Stephen L, Yoganathan, Ajit P

“…An understanding of how mechanical forces impact cells within valve leaflets would greatly benefit the development of a tissue-engineered heart valve. Previous…”
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Effects of constant static pressure on the biological properties of porcine aortic valve leaflets by Xing, Yun, He, Zhaoming, Warnock, James N, Hilbert, Stephen L, Yoganathan, Ajit P

“…An understanding of how mechanical forces impact cells within valve leaflets would greatly benefit the development of a tissue-engineered heart valve. In this…”
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Explant pathology study of decellularized carotid artery vascular grafts by Hilbert, Stephen L., Boerboom, Lawrence E., Livesey, Stephen A., Ferrans, Victor J.

“…The purpose of this study was to evaluate the morphologic findings in small‐diameter freeze‐dried decellularized carotid artery grafts implanted in goats as…”
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Effects of cryopreservation, decellularization and novel extracellular matrix conditioning on the quasi-static and time-dependent properties of the pulmonary valve leaflet by Converse, Gabriel L., Armstrong, Matt, Quinn, Rachael W., Buse, Eric E., Cromwell, Michael L., Moriarty, Sara J., Lofland, Gary K., Hilbert, Stephen L., Hopkins, Richard A.

“…Decellularized allografts offer potential as heart valve substitutes and scaffolds for cell seeding. The effects of decellularization on the quasi-static and…”
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Pulse Duplicator Hydrodynamic Testing of Bioengineered Biological Heart Valves by Buse, Eric E., Hilbert, Stephen L., Hopkins, Richard A., Converse, Gabriel L.

“…There are many heart valve replacements currently available on the market; however, these devices are not ideal for pediatric patients with congenital heart…”
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Calcium and phosphorus concentrations in native and decellularized semilunar valve tissues by Acharya, Gayathri, Armstrong, Matthew, McFall, Chris, Quinn, Rachael W, Hilbert, Stephen L, Converse, Gabriel L, Toth, Peter B, Sherman, Ashley K, Lee, Chi H, Lofland, Gary K, Hopkins, Richard A

“…Native, allograft, xenograft and bioprosthetic semilunar valves are all susceptible to calcific degeneration. However, intrinsic differences in baseline…”
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Heart valve collagens: cross-species comparison using immunohistological methods by White, Jacinta F, Werkmeister, Jerome A, Hilbert, Stephen L, Ramshaw, John A M

“…Tissue engineering is an emerging strategy for the development of replacement heart valves where the properties of native tissues are to be replicated. The…”
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Pediatric Cardiopulmonary Bypass Adaptations for Long-Term Survival of Baboons Undergoing Pulmonary Artery Replacement by WHITTAKER, Carrie, GRIST, Gary, LOFLAND, Gary K, HOPKINS, Richard A, BERT, Arthur, BRASKY, Kathleen, NEIGHBORS, Stacy, MCFALL, Christopher, HILBERT, Stephen L, DRAKE, William B, CROMWELL, Michael, MUELLER, Barbara

“…Cardiopulmonary bypass (CPB) protocols of the baboon (Papio cynocephalus anubis) are limited to obtaining experimental data without concern for long-term…”
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Prototype anionic detergent technique used to decellularize allograft valve conduits evaluated in the right ventricular outflow tract in sheep by Hilbert, Stephen L, Yanagida, Roh, Souza, Jason, Wolfinbarger, Lloyd, Jones, Alyce Linthurst, Krueger, Paula, Stearns, Gary, Bert, Arthur, Hopkins, Richard A

“…Biodegradable polymeric materials or extracellular matrix scaffolds are used in tissue-engineered heart valve designs, with the expectation of replicating the…”
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Allograft heart valves: The role of apoptosis-mediated cell loss by Hilbert, Stephen L., Luna, Rafael E., Zhang, Jun, Wang, Yining, Hopkins, Richard A., Yu, Zu-Xi, Ferrans, Victor J.

“…Objective: The purpose of this study was to determine whether apoptosis of endothelial and connective tissue cells is responsible for the loss of cellularity…”
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The indeterminate phase of Chagas' disease: ultrastructural characterization of cardiac changes in the canine model by Andrade, Z A, Andrade, S G, Sadigursky, M, Wenthold, Jr, R J, Hilbert, S L, Ferrans, V J

“…The indeterminate phase of Chagas' disease is defined as the prolonged period of clinically silent infection that follows the phase of acute primary infection…”
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Hyperplasia of type II pneumocytes in pulmonary lymphangioleiomyomatosis by Matsui, K, K Riemenschneider, W, Hilbert, S L, Yu, Z X, Takeda, K, Travis, W D, Moss, J, Ferrans, V J

“…Little is known of the morphology of the pneumocytes lining the parenchymal cysts in lymphangioleiomyomatosis (LAM). To evaluate the structural characteristics…”
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Bioengineered Human and Allogeneic Pulmonary Valve Conduits Chronically Implanted Orthotopically in Baboons: Hemodynamic Performance and Immunological Consequences by Hopkins, Richard A., Bert, Arthur A., Hilbert, Stephen L., Quinn, Rachael W., Brasky, Kathleen M., Drake, William B., Lofland, Gary K.

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Enhanced Autologous Re-endothelialization of Decellularized and Extracellular Matrix Conditioned Allografts Implanted Into the Right Ventricular Outflow Tracts of Juvenile Sheep by Quinn, Rachael W., Hilbert, Stephen L., Converse, Gabriel L., Bert, Arthur A., Buse, Eric, Drake, William B., Armstrong, Matt, Moriarty, Sara J., Lofland, Gary K., Hopkins, Richard A.

“…Decellularized allografts are promising options for pediatric valve replacement due to reduced immunogenicity and the potential for in vivo autologous…”
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Overview of the FDA Regulatory Process by Whittlesey, Kevin J, Lee, Mark H, Dang, Jiyoung M, Colehour, Maegen, Arcidiacono, Judith, Lazarus, Ellen, Kaplan, David S, Fink, Donald, Durfor, Charles N, Batra, Ashok, Hilbert, Stephen L, Grayeski, Deborah Lavoie, McFarland, Richard, Witten, Celia

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Hyperlasia of type II pneumocytes in pulmonary lymphangioleimyomatosis: Immunohistochemical and electron microscopic study by Matsui, Kazuhiro, Riemenschneider, William K, Hilbert, Stephen L, Zu-Xi, Yu

“…Little is known of the morphology of the pneumocytes lining the parenchymal cysts in lymphangioleiomyomatosis (LAM). To evaluate the structural characteristics…”
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