Search Results - "HIGMAN, Meghan"
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Low toxicity and favorable overall survival in relapsed/refractory B-ALL following CAR T cells and CD34-selected T-cell depleted allogeneic hematopoietic cell transplant
Published in Bone marrow transplantation (Basingstoke) (01-11-2020)“…To define the tolerability and outcome of allogeneic hematopoietic stem cell transplant (allo-HSCT) following CAR T-cell therapy, we retrospectively reviewed…”
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Pearson marrow pancreas syndrome in patients suspected to have Diamond-Blackfan anemia
Published in Blood (17-07-2014)“…Pearson marrow pancreas syndrome (PS) is a multisystem disorder caused by mitochondrial DNA (mtDNA) deletions. Diamond-Blackfan anemia (DBA) is a congenital…”
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Acute hepatic encephalopathy and multiorgan failure in sickle cell disease and COVID‐19
Published in Pediatric blood & cancer (01-05-2021)Get full text
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Chronic graft versus host disease
Published in British journal of haematology (01-05-2004)“…Summary The ability to cure increasing numbers of individuals for malignant and non‐malignant diseases with the use of stem cell transplantation has resulted…”
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Phase II Study of Pentostatin in Patients With Corticosteroid-Refractory Chronic Graft-Versus-Host Disease
Published in Journal of clinical oncology (20-09-2007)“…Therapy for patients with chronic graft-versus-host disease (cGVHD) is based on prolonged immunosuppression with corticosteroids. There is no standard therapy…”
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Epstein-Barr virus DNA in serum as an early prognostic marker in children and adolescents with Hodgkin lymphoma
Published in Blood advances (25-04-2017)“…Assay of cell-free DNA in blood offers an approach to assessment of tumor DNA. We sought to determine whether Epstein-Barr virus (EBV) DNA in cell-free blood…”
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A clinical algorithm identifies high risk pediatric oncology and bone marrow transplant patients likely to benefit from treatment of adenoviral infection
Published in Journal of pediatric hematology/oncology (01-11-2009)“…Adenoviral infections cause morbidity and mortality in blood and marrow transplantation and pediatric oncology patients. Cidofovir is active against…”
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Successful treatment of a child with late onset T-cell post-transplant lymphoproliferative disorder/lymphoma
Published in Pediatric Blood & Cancer (01-03-2008)“…We report a novel regimen for refractory post‐transplant T‐cell lymphoma (PTL). Our patient presented with non‐Epstein–Barr virus (EBV) related, T‐cell…”
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Treatment of hepatitis-associated aplastic anemia with high-dose cyclophosphamide
Published in Pediatric Blood & Cancer (01-12-2007)“…Objective Demonstrate that high‐dose cyclophosphamide (CY) is effective therapy for hepatitis‐associated aplastic anemia (HAA). Background HAA is a sequence of…”
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Pseudomonas aeruginosa pre-septal cellulitis and bacteremia in a pediatric oncology patient
Published in Pediatric Blood & Cancer (01-09-2005)Get full text
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Bone Marrow Engraftment Analysis after Granulocyte Transfusion
Published in The Journal of molecular diagnostics : JMD (01-08-2005)“…We present the case of a 6-year-old male who received an allogeneic bone marrow transplant as part of treatment for acute lymphoblastic leukemia. The patient…”
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Misinterpretation of a calvert-derived formula leading to Carboplatin overdose in two children
Published in Journal of pediatric hematology/oncology (01-10-2003)“…Carboplatin is currently recommended to be dosed according to renal function. In adults, dosing by the Calvert formula is based on evidence that carboplatin…”
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Allogeneic CD34-Selected HSCT Following CAR T-Cells Is Associated with Low TRM and Favorable OS in Pediatric/Young Adult Patients with Relapsed/Refractory B-ALL
Published in Blood (13-11-2019)“…Background: Chimeric antigen receptor (CAR) T-cells have transformed the therapeutic options for patients with relapsed or refractory (R/R) B-cell acute…”
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Direct Photolinkage of GTP to the Vaccinia Virus mRNA (Guanine-7-) Methyltransferase GTP Methyl Acceptor Site
Published in Biochemistry (Easton) (01-08-1994)“…Direct UV photolinkage of [alpha-32P]GTP to the methyl acceptor site of the vaccinia virus (guanine-7-) methyltransferase was attempted in order to identify…”
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Fludarabine, Melphalan and Low Dose Total Body Irradiation for Reduced Intensity Conditioning (RIC) Prior to Allogeneic Hematopoietic Cell Transplantation (AlloHCT)
Published in Blood (18-11-2011)“…Abstract 4570 RIC AlloHCT can provide a curative option for patients with hematologic diseases who are not candidates for myeloablative AlloHCT. However, this…”
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Pearson Marrow Pancreas Syndrome In a Cohort Of Diamond Blackfan Anemia Patients
Published in Blood (15-11-2013)“…Pearson marrow pancreas syndrome (PS) is a congenital multisystem disorder characterized by sideroblastic anemia, pancreatic insufficiency, metabolic acidosis,…”
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AHOD0031: A Phase III Study of Dose-Intensive Therapy for Intermediate Risk Hodgkin Lymphoma: A Report From the Children's Oncology Group
Published in Blood (19-11-2010)“…Abstract 766 The challenge in treating children with Hodgkin lymphoma (HL) is to continue progress in its curability while diminishing the risk for toxic…”
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Coordinate Regulation of NF-κB Subunit Expression in EBV Negative, but Not EBV Positive, Pediatric Hodgkin's Lymphoma
Published in Blood (16-11-2008)“…The nuclear factor-kB (NF-kB) pathway plays an integral role in Hodgkin's lymphoma (HL), and may enhance survival of Hodgkin Reed Sternberg (H/RS) cells…”
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Reduced-Intensity Conditioning with Fludarabine, Melphalan, and Total Body Irradiation for Allogeneic Hematopoietic Cell Transplantation: The Effect of Increasing Melphalan Dose on Underlying Disease and Toxicity
Published in Biology of blood and marrow transplantation (01-04-2019)“…•Fludarabine, melphalan, and total body irradiation is an acceptable reduced-intensity conditioning regimen than can induce full donor chimerism.•Less robust…”
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