Search Results - "HIGHLEY, M. S"

Treatment of Invasive Thymoma With Single-Agent Ifosfamide by HIGHLEY, M. S, UNDERHILL, C. R, HARPER, P. G, PARNIS, F. X, KARAPETIS, C, RANKIN, E, DUSSEK, J, BRYANT, B, ROWLAND, C, HODSON, N, HUGHES, J

“…To evaluate single-agent ifosfamide in the treatment of invasive thymoma. Fifteen patients (eight male and seven female) with histologically confirmed invasive…”
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Hyphenated techniques in anticancer drug monitoring: II. Liquid chromatography–mass spectrometry and capillary electrophoresis–mass spectrometry by Guetens, G, De Boeck, G, Highley, M.S, Wood, M, Maes, R.A.A, Eggermont, A.A.M, Hanauske, A, de Bruijn, E.A, Tjaden, U.R

“…High-performance liquid chromatography has become the separation technique of choice for the monitoring of generally thermolabile anticancer agents. With the…”
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Interaction between paclitaxel and warfarin by Thompson, M. E., Highley, M. S.

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Hyphenated techniques in anticancer drug monitoring: I. Capillary gas chromatography–mass spectrometry by Guetens, G, De Boeck, G, Wood, M, Maes, R.A.A, Eggermont, A.A.M, Highley, M.S, van Oosterom, A.T, de Bruijn, E.A, Tjaden, U.R

“…Most anticancer agents are relatively unstable substances and are subjected to intensive metabolism in vivo and degradation during sample pretreatment…”
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Intravesical drug delivery : Pharmacokinetic and clinical considerations by HIGHLEY, M. S, VAN OOSTEROM, A. T, MAES, R. A, DE BRUIJN, E. A

“…Intravesical drug administration is widely used in the treatment of patients with superficial bladder cancer, and aims to optimise drug delivery in the…”
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Activated oxazaphosphorines are transported predominantly by erythrocytes by Highley, M. S., Schrijvers, D., Van Oosterom, A. T., Harper, P. G., Momerency, G., Van Cauwenberghe, K., Maes, R. A. A., De Bruijn, E. A., Edelstein, M. B.

“…purpose Oxazaphosphorines are metabolised by a variety of pathways, one of which leads to activation and the formation of alkylating compounds. However, the…”
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Erythrocytes and the transport of drugs and endogenous compounds by HIGHLEY, M. S, DE BRUIJN, E. A

“…This review considers the significance and measurement of endogenous compounds and drugs on erythrocytes. Part I examines literature examples where a direct…”
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Combination chemotherapy with epirubicin, cisplatin and 5-fluorouracil for the palliation of advanced gastric and oesophageal adenocarcinoma by Highley, M S, Parnis, F X, Trotter, G A, Houston, S J, Penson, R T, Harper, P G, Mason, R C

“…The palliative efficacy of laser therapy with combination chemotherapy (cisplatin, epirubicin and continuous infusion of 5-fluorouracil) was assessed in 34…”
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Pharmacokinetics and bioavailability of oral 5′‐deoxy‐5‐fluorouridine in cancer patients by VAN DER HEYDEN, S. A. M, HIGHLEY, M. S, DE BRUIJN, E. A, TJADEN, U. R, REEUWIJK, H. J. E. M, VAN SLOOTEN, H, OOSTEROM, A. T. V, MAES, R. A. A

“…Aims Oral administration of 5‐fluorouracil (FUra), an important cytotoxic agent, is limited by a wide variation in bioavailability. 5′‐deoxy‐5‐fluorouridine…”
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Multicenter phase II study of gemcitabine in previously untreated patients with advanced epithelial ovarian cancer by Underhill, C R, Parnis, F X, Highley, M S, Ahern, J, Harper, P G, Hansen, H, Lund, B, Dombernowsky, P, Hirsch, F, Hansen, M, Carmichael, J, Williams, C

“…Gemcitabine has activity in advanced ovarian cancer, with responses in platinum-resistant disease. This study assessed the activity of gemcitabine in…”
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Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans by Highley, M S, Momerency, G, Van Cauwenberghe, K, Van Oosterom, A T, de Bruijn, E A, Maes, R A, Blake, P, Mansi, J, Harper, P G

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Weekly cisplatin with oral etoposide: a well-tolerated and highly effective regimen in relapsed ovarian cancer by Verborg, W A, Campbell, L R, Highley, M S, Rankin, E M

“…The optimal treatment of progressive ovarian cancer after first-line platinum-based therapy remains a challenge. We collected prospectively data on patients…”
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Preferential location of circulating activated cyclophosphamide within the erythrocyte by Highley, M S, Harper, P G, Slee, P H, DeBruijn, E

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Awareness of BACUP in primary health care: the potential of voluntary services by Stone, M, Highley, M S, Harper, P G, Poole, D

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Partitioning of ifosfamide and its metabolites between red blood cells and plasma by Momerency, G, Van Cauwenberghe, K, Highley, M S, Harper, P G, Van Oosterom, A T, De Bruijn, E A

“…A recently developed GC-MS analytical method for the quantitative determination of oxazaphosphorines and their metabolites in blood plasma, using stable…”
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A Phase II Trial of Continuous 5-Fluorouracil in Recurrent or Metastatic Transitional Cell Carcinoma of the Urinary Tract by Highley, M.S, Griffiths, G.O, Uscinska, B.M, Huddart, R.A, Barber, J.B.P, Parmar, M.K.B, Harper, P.G

“…Abstract Aims To assess the activity of a continuous infusion of 5-fluorouracil in patients with recurrent locally advanced or metastatic transitional cell…”
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High-dose folinic acid with 5-fluorouracil bolus and continuous infusion in the treatment of advanced gastric and oesophageal adenocarcinoma by Highley, M S, Hill, M E, Ziras, N, Samandas, N, Mason, R C, Owen, W, Dussek, J, Barker, S, Harper, P G

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Drugs prescribed for self poisoners by Prescott, L F, Highley, M S

“…Of 230 adults admitted for self poisoning over two months, 153 (67%) had previously been taking a total of 309 prescribed drugs. Of these patients, 119 (78%)…”
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Vascular Endothelial Growth Factor and Angiogenesis by Hoeben, Ann, Landuyt, Bart, Highley, Martin S, Wildiers, Hans, Van Oosterom, Allan T, De Bruijn, Ernst A

“…Angiogenesis is a hallmark of wound healing, the menstrual cycle, cancer, and various ischemic and inflammatory diseases. A rich variety of pro- and…”
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Description of an instrument for separation of red cells from plasma and measurement of red cell volume by Driessen, O, Highley, M S, Harper, P G, Maes, R A, De Bruijn, E A

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