Search Results - "HIGGINS, J. P. T"

Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies by Higgins, J. P. T., Jackson, D, Barrett, J. K., Lu, G, Ades, A. E., White, I. R.

“…Meta‐analyses that simultaneously compare multiple treatments (usually referred to as network meta‐analyses or mixed treatment comparisons) are becoming…”
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Simultaneous comparison of multiple treatments: combining direct and indirect evidence by Caldwell, Deborah M, Ades, A E, Higgins, J P T

“…Caldwell and Higgins discuss how policy makers can decide which of five treatments is the best. Standard meta-analysis provides little help but evidence based…”
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The Interpretation of Random-Effects Meta-Analysis in Decision Models by Ades, A. E., Lu, G., Higgins, J. P. T.

“…This article shows that the interpretation of the random-effects models used in meta-analysis to summarize heterogeneous treatment effects can have a marked…”
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Covariate heterogeneity in meta-analysis: Criteria for deciding between meta-regression and individual patient data by Simmonds, M. C., Higgins, J. P. T.

“…Meta‐analyses of clinical trials are increasingly seeking to go beyond estimating the effect of a treatment and may also aim to investigate the effect of other…”
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Glutathione S-Transferase M1 (GSTM1) Polymorphisms and Lung Cancer: A Literature-based Systematic HuGE Review and Meta-Analysis by Carlsten, C., Sagoo, G. S., Frodsham, A. J., Burke, W., Higgins, J. P. T.

“…Multiple genes have been studied for potential associations with lung cancer. The gene most frequently associated with increased risk has been glutathione…”
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Genetic associations in peripheral joint osteoarthritis and spinal degenerative disease: a systematic review by Ryder, J J, Garrison, K, Song, F, Hooper, L, Skinner, J, Loke, Y, Loughlin, J, Higgins, J P T, MacGregor, A J

“…We conducted a systematic review of genetic association studies for osteoarthritis of the peripheral joints (OA) and spinal degenerative disease (SDD)…”
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Estimation and adjustment of bias in randomized evidence by using mixed treatment comparison meta-analysis by Dias, S., Welton, N. J., Marinho, V. C. C., Salanti, G., Higgins, J. P. T., Ades, A. E.

“…There is good empirical evidence that specific flaws in the conduct of randomized controlled trials are associated with exaggeration of treatment effect…”
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Cognitive-behavioural interventions for children who have been sexually abused by Macdonald, G M, Higgins, J P T, Ramchandani, P

“…Despite differences in perceptions of what constitutes child sexual abuse there is a general consensus amongst clinicians and researchers that this is a…”
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Control of carbapenemase-producing Enterobacteriaceae outbreaks in acute settings: An evidence review by French, Clare E, Coope, Caroline, Dr, Conway, Lucy, Higgins, Julian PT, McCulloch, Janet, Okoli, George, Patel, Bharat C, Oliver, Isabel

“…Abstract Background In recent years infections with carbapenemase-producing Enterobacteriaceae (CPE) have been increasing globally and present a major public…”
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Adjusting trial results for biases in meta‐analysis: combining data‐based evidence on bias with detailed trial assessment by Rhodes, K. M., Savović, J., Elbers, R., Jones, H. E., Higgins, J. P. T., Sterne, J. A. C., Welton, N. J., Turner, R. M.

“…Summary Flaws in the conduct of randomized trials can lead to biased estimation of the intervention effect. Methods for adjustment of within‐trial biases in…”
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Label‐invariant models for the analysis of meta‐epidemiological data by Rhodes, K.M., Mawdsley, D., Turner, R.M., Jones, H.E., Savović, J., Higgins, J.P.T.

“…Rich meta‐epidemiological data sets have been collected to explore associations between intervention effect estimates and study‐level characteristics. Welton…”
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A systematic review of the use of opioids in the management of dyspnoea by Jennings, A-L, Davies, A N, Higgins, J P T, Gibbs, J S R, Broadley, K E

“…Background: Opioids are commonly used to treat dyspnoea in palliative medicine but there has been no formal evaluation of the evidence for their effectiveness…”
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Applicability and Feasibility of Systematic Review for Performing Evidence-Based Risk Assessment in Food and Feed Safety by Aiassa, E, Higgins, J.P.T, Frampton, G.K, Greiner, M, Afonso, A, Amzal, B, Deeks, J, Dorne, J.-L, Glanville, J, Lövei, G. L, Nienstedt, K, O’connor, A.M, Pullin, A.S, Rajić, A, Verloo, D

“…Food and feed safety risk assessment uses multi-parameter models to evaluate the likelihood of adverse events associated with exposure to hazards in human…”
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Systematic review with meta‐analysis: the gastrointestinal benefits of COX‐2 selective inhibitors with concomitant use of low‐dose aspirin by Yuan, J. Q., Yang, M., Threapleton, D. E., Qi, X. S., Ye, D. Q., Mao, C., Tang, J. L., Higgins, J. P. T.

“…Summary Background It is uncertain whether concurrent use of low‐dose aspirin removes the gastrointestinal benefit displayed by COX‐2 selective inhibitors…”
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Seven Lipoprotein Lipase Gene Polymorphisms, Lipid Fractions, and Coronary Disease: A HuGE Association Review and Meta-Analysis by Sagoo, Gurdeep S., Tatt, Iain, Salanti, Georgia, Butterworth, Adam S., Sarwar, Nadeem, van Maarle, Merel, Jukema, J. Wouter, Wiman, Björn, Kastelein, John J. P., Bennet, Anna M., de Faire, Ulf, Danesh, John, Higgins, Julian P. T.

“…Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism and a major candidate gene for coronary heart disease (CHD). The authors assessed…”
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Levonorgestrel‐releasing (20 μg/day) intrauterine systems (Mirena) compared with other methods of reversible contraceptives by French, R. S., Cowan, F. M., Mansour, D., Higgins, J. P. T., Robinson, A., Procter, T., Morris, S., Guillebaud, J.

“…Objective To assess the relative contraceptive effectiveness, tolerability and acceptability of the levonorgestrel‐releasing (20 μg per day) intrauterine…”
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Commentary: Heterogeneity in meta-analysis should be expected and appropriately quantified by Higgins, Julian P T

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Randomised controlled trial of novel, simple, and well supervised weight reducing diets in outpatients by Summerbell, Carolyn D, Watts, Carolyn, Higgins, Julian P T, Garrow, John S

“…Abstract Objectives: To investigate the contribution of novelty and simplicity to compliance with a low energy diet among obese outpatients. Design: Three arm…”
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Interpretation of random effects meta-analyses by Riley, Richard D, Higgins, Julian P T, Deeks, Jonathan J

“…Summary estimates of treatment effect from random effects meta-analysis give only the average effect across all studies. Inclusion of prediction intervals,…”
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The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials by Higgins, Julian P T, Altman, Douglas G, Gøtzsche, Peter C, Jüni, Peter, Moher, David, Oxman, Andrew D, Savović, Jelena, Schulz, Kenneth F, Weeks, Laura, Sterne, Jonathan A C

“…Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The…”
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