Search Results - "HIGGINS, Gloria C"

Anakinra as first‐line disease‐modifying therapy in systemic juvenile idiopathic arthritis: Report of forty‐six patients from an international multicenter series by Nigrovic, Peter A., Mannion, Melissa, Prince, Femke H. M., Zeft, Andrew, Rabinovich, C. Egla, van Rossum, Marion A. J., Cortis, Elisabetta, Pardeo, Manuela, Miettunen, Paivi M., Janow, Ginger, Birmingham, James, Eggebeen, Aaron, Janssen, Erin, Shulman, Andrew I., Son, Mary Beth, Hong, Sandy, Jones, Karla, Ilowite, Norman T., Cron, Randy Q., Higgins, Gloria C.

“…Objective To examine the safety and efficacy of the interleukin‐1 (IL‐1) receptor antagonist anakinra as first‐line therapy for systemic juvenile idiopathic…”
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Gene Copy-Number Variation and Associated Polymorphisms of Complement Component C4 in Human Systemic Lupus Erythematosus (SLE): Low Copy Number Is a Risk Factor for and High Copy Number Is a Protective Factor against SLE Susceptibility in European Americans by Yang, Yan, Chung, Erwin K., Wu, Yee Ling, Savelli, Stephanie L., Nagaraja, Haikady N., Zhou, Bi, Hebert, Maddie, Jones, Karla N., Shu, Yaoling, Kitzmiller, Kathryn, Blanchong, Carol A., McBride, Kim L., Higgins, Gloria C., Rennebohm, Robert M., Rice, Robert R., Hackshaw, Kevin V., Roubey, Robert A.S., Grossman, Jennifer M., Tsao, Betty P., Birmingham, Daniel J., Rovin, Brad H., Hebert, Lee A., Yung Yu, C.

“…Interindividual gene copy-number variation (CNV) of complement component C4 and its associated polymorphisms in gene size (long and short) and protein isotypes…”
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Development of consensus treatment plans for juvenile localized scleroderma: A roadmap toward comparative effectiveness studies in juvenile localized scleroderma by Li, Suzanne C., Torok, Kathryn S., Pope, Elena, Dedeoglu, Fatma, Hong, Sandy, Jacobe, Heidi T., Rabinovich, C. Egla, Laxer, Ronald M., Higgins, Gloria C., Ferguson, Polly J., Lasky, Andrew, Baszis, Kevin, Becker, Mara, Campillo, Sarah, Cartwright, Victoria, Cidon, Michael, Inman, Christi J., Jerath, Rita, O'Neil, Kathleen M., Vora, Sheetal, Zeft, Andrew, Wallace, Carol A., Ilowite, Norman T., Fuhlbrigge, Robert C.

“…Objective Juvenile localized scleroderma (LS) is a chronic inflammatory skin disorder associated with substantial morbidity and disability. Although a wide…”
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Assessment of transition readiness in adolescents and young adults with chronic health conditions by Jensen, Paul T, Paul, Gabrielle V, LaCount, Stephanie, Peng, Juan, Spencer, Charles H, Higgins, Gloria C, Boyle, Brendan, Kamboj, Manmohan, Smallwood, Christopher, Ardoin, Stacy P

“…Transition from pediatric to adult health care is a vulnerable period for adolescents and young adults. Challenges include paucity of validated measures to…”
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The Localized Scleroderma Skin Severity Index and Physician Global Assessment of Disease Activity: A Work in Progress Toward Development of Localized Scleroderma Outcome Measures by ARKACHAISRI, Thaschawee, VILAIYUK, Soamarat, ROSEN, Paul, SPALDING, Steven J, HENNON, Teresa R, TOROK, Kathryn S, CASSIDY, Elaine, MEDSGER, Thomas A, SUZANNE LI, O'NEIL, Kathleen M, POPE, Elena, HIGGINS, Gloria C, PUNARO, Marilynn, RABINOVICH, Egla C, ROSENKRANZ, Margalit, KIETZ, Daniel A

“…Objective. To develop and evaluate a Localized Scleroderma (LS) Skin Severity Index (LoSSI) and global assessments’ clinimetric property and effect on…”
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Treatment of Pediatric Localized Scleroderma: Results of a Survey of North American Pediatric Rheumatologists by LI, Suzanne C, FELDMAN, Brian M, HIGGINS, Gloria C, HAINES, Kathleen A, PUNARO, Marilynn G, O'NEIL, Kathleen M

“…Objective. We surveyed pediatric rheumatologists (PR) in North America to learn how they treat pediatric localized scleroderma (LS), a disease associated with…”
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Health-related Quality of Life and Its Relationship to Patient Disease Course in Childhood-onset Systemic Lupus Erythematosus by BRUNNER, Hermine I, HIGGINS, Gloria C, WIERS, Kristina, LAPIDUS, Sivia K, OLSON, Judyann C, ONEL, Karen, PUNARO, Marilynn, YING, Jun, KLEIN-GITELMAN, Marisa S, SEID, Michael

“…Objective. To (1) estimate the health-related quality of life (HRQOL) of children with childhood-onset systemic lupus erythematosus (cSLE) and compare it to…”
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Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study by Li, Suzanne C, Fuhlbrigge, Robert C, Laxer, Ronald M, Pope, Elena, Ibarra, Maria F, Stewart, Katie, Mason, 2nd, Thomas, Becker, Mara L, Hong, Sandy, Dedeoglu, Fatma, Torok, Kathryn S, Rabinovich, C Egla, Ferguson, Polly J, Punaro, Marilynn, Feldman, Brian M, Andrews, Tracy, Higgins, Gloria C

“…We designed and initiated a pilot comparative effectiveness study for juvenile localized scleroderma (jLS), for which there is limited evidence on best…”
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Complications of Treatments for Pediatric Rheumatic Diseases by Higgins, Gloria C.

“…Medications to treat children with rheumatic disease include disease-modifying antirheumatic drugs, glucocorticosteroids, and biologic response modifiers that…”
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Morbidity and Disability in Juvenile Localized Scleroderma: The Case for Early Recognition and Systemic Immunosuppressive Treatment by Li, Suzanne C., O'Neil, Kathleen M., Higgins, Gloria C.

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Health status of patients with juvenile rheumatoid arthritis at 1 and 5 years after diagnosis by BOWYER, Suzanne L, ROETTCHER, Philip A, WAGNER-WEINER, Linda, RABINOVICH, Egla, PASSO, Murray, LOVELL, Daniel J, MADSON, Katherine, MCCURDY, Deborah, ZEMEL, Lawrence, SCHIKLER, Kenneth N, SZER, Ilona, KURTIN, Paul, HIGGINS, Gloria C, LINDSLEY, Carol, ADAMS, Barbara, MYERS, Linda K, WALLACE, Carol, RENNEBOHM, Robert, MOORE, Terry L, PEPMUELLER, Peri H, SPENCER, Charles

“…OBJECTIVE: To describe the health and functional status of children with juvenile rheumatoid arthritis (JRA) diagnosed in the early 1990s. METHODS: Patients…”
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Extracutaneous involvement is common and associated with prolonged disease activity and greater impact in juvenile localized scleroderma by Li, Suzanne C, Higgins, Gloria C, Chen, Mallory, Torok, Kathryn S, Rabinovich, C Egla, Stewart, Katie, Laxer, Ronald M, Pope, Elena, Haines, Kathleen A, Punaro, Marilynn, O'Neil, Kathleen M

“…The aim of this study was to evaluate factors associated with extracutaneous involvement (ECI) in juvenile localized scleroderma (jLS). A prospective,…”
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Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis by Wallace, Carol A., Giannini, Edward H., Spalding, Steven J., Hashkes, Philip J., O'Neil, Kathleen M., Zeft, Andrew S., Szer, Ilona S., Ringold, Sarah, Brunner, Hermine I., Schanberg, Laura E., Sundel, Robert P., Milojevic, Diana, Punaro, Marilynn G., Chira, Peter, Gottlieb, Beth S., Higgins, Gloria C., Ilowite, Norman T., Kimura, Yukiko, Hamilton, Stephanie, Johnson, Anne, Huang, Bin, Lovell, Daniel J.

“…Objective To determine whether aggressive treatment initiated early in the course of rheumatoid factor (RF)–positive or RF‐negative polyarticular juvenile…”
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Initial Results from a Pilot Comparative Effectiveness Study of 3 Methotrexate-based Consensus Treatment Plans for Juvenile Localized Scleroderma by Li, Suzanne C, Torok, Kathryn S, Rabinovich, C Egla, Dedeoglu, Fatma, Becker, Mara L, Ferguson, Polly J, Hong, Sandy D, Ibarra, Maria F, Stewart, Katie, Pope, Elena, Higgins, Gloria C, Laxer, Ronald M, Mason, 2nd, Thomas, Fuhlbrigge, Robert C, Andrews, Tracy

“…To perform a comparative effectiveness feasibility study in juvenile localized scleroderma (LS), using standardized treatment regimens (consensus treatment…”
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New Features for Measuring Disease Activity in Pediatric Localized Scleroderma by Li, Suzanne C, Li, Xiaohu, Pope, Elena, Stewart, Katie, Higgins, Gloria C, Rabinovich, C Egla, O'Neil, Kathleen M, Haines, Kathleen A, Laxer, Ronald M, Punaro, Marilynn, Jacobe, Heidi, Andrews, Tracy, Wittkowski, Knut, Nyirenda, Themba, Foeldvari, Ivan, Torok, Kathryn S

“…To identify clinical features that define disease activity in pediatric localized scleroderma (LS), and determine their specificity and importance. We…”
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Overview of Pediatric Rheumatology for the Primary Care Provider by Li, Suzanne C., Higgins, Gloria C.

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Clinically Inactive Disease in a Cohort of Children with New-onset Polyarticular Juvenile Idiopathic Arthritis Treated with Early Aggressive Therapy: Time to Achievement, Total Duration, and Predictors by WALLACE, Carol A, GIANNINI, Edward H, SUNDEL, Robert P, MILOJEVIC, Diana S, PUNARO, Marilynn G, CHIRA, Peter, GOTTLIEB, Beth S, HIGGINS, Gloria C, ILOWITE, Norman T, KIMURA, Yukiko, JOHNSON, Anne, BIN HUANG, SPALDING, Steven J, LOVELL, Daniel J, HASHKES, Philip J, O'NEIL, Kathleen M, ZEFT, Andrew S, SZER, Ilona S, RINGOLD, Sarah, BRUNNER, Hermine I, SCHANBERG, Laura E

“…To determine the elapsed time while receiving aggressive therapy to the first observation of clinically inactive disease (CID), total duration of CID and…”
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Extension study of participants from the trial of early aggressive therapy in juvenile idiopathic arthritis by Wallace, Carol A, Ringold, Sarah, Bohnsack, John, Spalding, Steven J, Brunner, Hermine I, Milojevic, Diana, Schanberg, Laura E, Higgins, Gloria C, O'Neil, Kathleen M, Gottlieb, Beth S, Hsu, Joyce, Punaro, Marilynn G, Kimura, Yukiko, Hendrickson, Audrey

“…To follow children with juvenile idiopathic arthritis (JIA) who had completed at least 6 months of the TRial of Early Aggressive Therapy (TREAT) clinical study…”
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Randomized, Double‐Blind, Dose‐Escalation Trial of Triptorelin for Ovary Protection in Childhood‐Onset Systemic Lupus Erythematosus by Brunner, Hermine I., Silva, Clovis A., Reiff, Andreas, Higgins, Gloria C., Imundo, Lisa, Williams, Calvin B., Wallace, Carol A., Aikawa, Nadia E., Nelson, Shannen, Klein‐Gitelman, Marisa S., Rose, Susan R.

“…Objective To determine the dose of triptorelin that is sufficient to maintain complete ovarian suppression in female patients with childhood‐onset systemic…”
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Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein by Ardoin, Stacy P, Schanberg, Laura Eve, Sandborg, Christy I, Barnhart, Huiman X, Evans, Greg W, Yow, Eric, Mieszkalski, Kelly L, Ilowite, Norman T, Eberhard, Anne, Imundo, Lisa F, Kimura, Yuki, Levy, Deborah, von Scheven, Emily, Silverman, Earl, Bowyer, Suzanne L, Punaro, L, Singer, Nora G, Sherry, David D, McCurdy, Deborah K, Klein-Gitelman, Marissa, Wallace, Carol, Silver, Richard M, Wagner-Weiner, Linda, Higgins, Gloria C, Brunner, Hermine I, Jung, Lawrence, Soep, Jennifer B, Reed, Ann M, Thompson, Susan D

“…Participants in the Atherosclerosis Prevention in Paediatric Lupus Erythematosus (APPLE) trial were randomised to placebo or atorvastatin for 36 months. The…”
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